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  • 1
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 31 (1991), S. 1301-1309 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: This paper reports both experimental and numerical investigations on delamination mechanisms in [05, 905, 05] carbon fiber(CF)/poly(etheretherketone) (PEEK) laminate subjected to low-velocity impact. It was found that the CF/PEEK composite exhibits the same damage mechanisms as epoxy-based composites, but superior delamination resistance. For the crossply laminate, the impact delamination results from a Mode II interlaminar fracture process, and a close association exists between the interlaminar shear stress field and the delamination growth. The prediction of impact-induced delamination sizes is discussed.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2014-03-19
    Description: BACKGROUND Although SDF-1/CXCR4 pathway is a potential mechanism of tumor proliferation and progression, the mechanism of controlling CXCR4 expression is not fully understood. This study was to confirm that miR-494-3p might be a potentially post-transcriptional regulator of CXCR4 and over-expression of miR-494 might suppress prostate cancer progression and metastasis. MATERIALS AND METHODS We firstly postulated the post-transcriptional regulation of CXCR4 by miR-494-3p through bioinformatics analysis, and then it was demonstrated that miR-494-3p could regulate the CXCR4 mRNA post-transcriptionally by binding to the predicted site by dual reporter gene assays. The biological effect of miR-494-3p on prostate cancer cells proliferation, apoptosis, migration, and invasion was measured by MTT, TUNEL, flow cytometry, migration, and invasion assays. RESULTS It was shown that the mRNA and protein expression levels of CXCR4 were significantly up-regulated in PC-3 and DU145, whereas barely detected in LNCaP and RWPE-1. However, the CXCR4 protein levels were inversely related to the mature miR-494-3p expression levels in RWPE-1 and prostate cancer cells. The constitutive over-expression of miR-494-3p could down-regulate the protein level of CXCR4 in PC-3 and DU145. MiR-494-3p also could bind to the seed sequences in the 3′-UTR of the CXCR4 gene. Artificial over-expression of miR-494-3p could inhibit the growth, promote the apoptosis, and inhibit the migration and invasion of PC-3 and DU145 cells in vivo. CONCLUSIONS Our results suggested that miR-494-3p might play crucial role in prostate cancer by post-transcriptional regulation to CXCR4 mRNA. MiR-494-3p/CXCR4 pathway may be a potential therapeutic target to prevent prostate cancer progression and metastasis. Prostate © 2014 Wiley Periodicals, Inc.
    Print ISSN: 0270-4137
    Electronic ISSN: 1097-0045
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 3
    Publication Date: 2014-01-31
    Description: A computational fluid dynamics model was developed to investigate the hydrodynamic characteristics of a novel orthogonal fixed-valve tray, which offers a larger effective contact perimeter under the same orifice area than its previously reported counterparts. The liquid-gas phases were simulated in the Eulerian framework, with the interphase momentum transfer source term based on the experimentally obtained liquid hold-up correlation. The simulation results were consistent with the experimental data. In addition, the gas hold-up profile of this new design was compared with its triangular cousin under the conditions of a typical run, showing that the former has a higher froth height, which indicated better interphase contact on the tray. The hydrodynamics of a fixed-valve tray has great influence on the liquid-gas interaction. The characteristics of an orthogonal fixed-valve tray were modelled using computational fluid dynamics and an Eulerian framework. Comparison of the gas holdup profiles of the orthogonal and the triangular fixed-valve tray indicated better interphase contact on the tray for the cross-orthogonal design.
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley-Blackwell
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  • 4
    Publication Date: 2013-10-19
    Description: ABSTRACT Field measurements of the diffusive boundary layer (DBL) and bottom boundary layer (BBL) in two distinctly different coastal ocean environments are analyzed. The dynamic conditions of the BBL have a strong influence on the DBL thickness ( δ DBL ) and oxygen diffusive fluxes at the sediment-water interface. Three different estimates of the Batchelor length ( L B ) in the BBL are obtained from the measured dissipation rate of turbulent kinetic energy ( ε m ), turbulent friction velocity ( u * ), and tidal velocity ( U m ) and bottom roughness length ( z 0 ). The two estimates of L B from ε m and u * have low correlations with δ DBL . The estimate of L B from U m and z 0 has a higher correlation with δ DBL at both sites, suggesting a simple estimation of δ DBL .
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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  • 5
    Publication Date: 2015-11-21
    Description: Purpose To determine whether intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) could detect parotid gland abnormalities in Sjögren's syndrome (SS) patients who were not identified by conventional MRI. Materials and Methods Ten consecutive patients with clinically proven SS who were not identified by conventional MRI were assessed by IVIM MRI with a 3.0T MRI scanner. Quantitative parameters (tissue diffusivity, D; pseudodiffusion coefficient, D*; perfusion fraction, f) derived from IVIM MRI were compared between the SS group and healthy control group ( n  = 15). A receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of each significant parameter. Results Excellent inter- and intrareader agreements were obtained during the measurement of D, f, and D* values (interreader, 0.980, 0.942, and 0.883; intrareader, 0.991, 0.952, and 0.896, respectively). All three parameters of the SS group were significantly higher than those of the healthy group (D, 1.049 ± 0.056 × 10 −3 mm 2 /s vs. 0.976 ± 0.116 × 10 −3 mm 2 /s, P  = 0.012; D*, 20.410 ± 1.786 × 10 −3 mm 2 /s vs. 18.764 ± 2.433 × 10 −3 mm 2 /s, P  = 0.013; f, 0.207 ± 0.003 vs. 0.182 ± 0.002, P  = 0.004). ROC analysis showed that the f value had the best diagnostic performance (AUC, 0.712; Sensitivity, 0.80; Specificity, 0.57; Cutoff value, 0.185) in detecting the parotid gland abnormalities in early SS patients. Conclusion IVIM MRI detected parotid gland abnormalities in early-stage SS patients. J. Magn. Reson. Imaging 2015.
    Print ISSN: 1053-1807
    Electronic ISSN: 1522-2586
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 6
    Publication Date: 2016-08-12
    Description: Titanium dioxide nanoparticles with disordered outermost layer sturctures have significantly enhanced light absorption and photocatalytic properties and thus receiving enhanced attention in recent years. Engineering the outermost layers using in situ magnesium doping to tailor the band-edge of TiO 2 nanoparticles was achieved via a flame aerosol reactor (FLAR). We proposed that the distribution of doped elements in nanoparticles could be controlled in a high temperature flame process, and which could be predicted by the comparison of different characteristic time scales, such as reaction time, coagulation time, and sintering time. In situ magnesium doping on the outermost layers effectively tailored the conduction band and electron structure of the TiO 2 nanoparticles, and simultaneously improved the maximum photocurrent as well as the maximum photovoltage in dye-sensitized solar cells (DSSCs). These improvements were largely attributed to red-shifted light absorption, and rapid photoelectron injection into the conduction band. This article is protected by copyright. All rights reserved.
    Print ISSN: 0001-1541
    Electronic ISSN: 1547-5905
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
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  • 7
    Publication Date: 2018-01-05
    Description: A novel method is developed to realize a III-V/Si dual-junction photovoltaic cell by combining epitaxial lift-off (ELO) and print-transfer-assisted bonding methods. The adoption of ELO enables III-V wafers to be recycled and reused, which can further lower the cost of III-V/Si photovoltaic panels. For demonstration, high crystal quality, micrometer-thick, GaAs/AlGaAs/GaAs films are lifted off, transferred, and directly bonded onto Si wafer without the use of any adhesive or bonding agents. The bonding interface is optically transparent and conductive both thermally and electrically. Prototype AlGaAs/Si dual-junction tandem solar cells have been fabricated and exhibit decent performance. A novel method is developed to realize an III-V/Si multijunction photovoltaic device by combining the epitaxial lift-off (ELO) and print-transfer-assisted bonding methods. The adoption of ELO enables III-V wafers to be recycled and reused, which is promising to further lower the cost of III-V/Si photovoltaic panels.
    Electronic ISSN: 2050-0505
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Wiley-Blackwell
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  • 8
    Publication Date: 2011-05-06
    Description: From 1961 to 2008, the overall frequency of dust storms in northern China has shown an unquestionable reduction. However, the Hunshdak Sandy Lands of northern China display an increasing frequency in dust storm activities, especially during the period 2001 to 2008. In an attempt to explore the cause of this increase, a comprehensive investigation was conducted by examining the climate variables, the average normalized difference vegetation index (NDVI) and the local inhabitant migrations. The climate variables include local precipitation, temperature, aridity, evaporation, relative humidity, soil moisture and wind speed. Moreover, by analyzing the 2001–2008 average anomaly charts (relative to the 30 year climatology of 1971–2000) of the upper air and surface conditions, an advantageous atmospheric circulation background for drought development over the Hunshdak was confirmed. Meanwhile, a multivariable step-regression model was employed to distinguish the significant variables of the climate elements mentioned before. The model output suggests that aridity is the leading factor impacting the Hunshdak dust storm frequency. During 2001 to 2008, the lack of local precipitation, higher temperature and strong evaporation deteriorated the local surface condition to below that before 2000, which is verified by the reduction of vegetation cover (NDVI), soil moisture and relative humidity. Furthermore, compared to the 30 year climatology of the wind speed observed during dust storm occurrence time, the mean velocity of 2001–2008 was reduced by 3.0 m s −1 , indicating that even with relatively weaker winds, dust storms still occurred primarily due to the degeneration of surface conditions around the Hunshdak. Copyright © 2011 Royal Meteorological Society
    Print ISSN: 1350-4827
    Electronic ISSN: 1469-8080
    Topics: Geography , Physics
    Published by Wiley-Blackwell
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  • 9
    Publication Date: 2013-04-30
    Description: A novel catalyst for bisphenol-A synthesis was prepared by bis (2-mercapto-ethyl) amine adsorbed on macroporous sulfonic resin through neutralization reaction. The physicochemical properties of two resin catalysts before and after bis (2-mercapto-ethyl) amine absorption were compared by scanning electron microscope and nitrogen adsorption. The kinetic of the new catalyst preparation process was studied and found this is a chemical adsorption and endothermic process. The adsorption rate is mainly controlled by the intra-particle diffusion, affected by boundary layer diffusion and chemical reaction as well. The thermodynamic activation parameters were calculated. Compared with unmodified catalyst, the modified resin catalyst showed higher selectivity and acetone conversion in the continuous bisphenol-A synthesis process. © 2013 American Institute of Chemical Engineers AIChE J, 2013
    Print ISSN: 0001-1541
    Electronic ISSN: 1547-5905
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
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  • 10
    Publication Date: 2014-02-16
    Description: [1]  Stress relaxation experiments are reported that culminate in energetic failure in rocks analogous to the loading cycle and subsequent localization or reactivation on brittle faults embedded in an elastic medium. Universally, rapid primary deformation arrests and transitions into a long secondary deformation phase that ultimately accelerates to catastrophic rupture. Primary deformation ( u ) conforms to Andrade's law as d u /d t ~  ( t c - t 0 ) θ with a standard exponent of 2/3 . In the long, and readily observable, secondary phase the samples both deform and analogously shed load near-linearly in time. This stress relaxation rate exhibits a robust power-law dependency with time-to-rupture and exhibits the same 2/3 power-law exponent observed in the primary phase. Similarly, the brittle strain energy released in the tertiary collapse scales with a normalized secondary stress relaxation rate. Together, these observations suggest a way to predict both the timing of rupture and its energetics from the observed stress (or strain) rate during the secondary relaxation stage.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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