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  • Springer  (1)
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    ISSN: 1432-0533
    Keywords: Porencephaly ; Perfusion failure ; Circle Willis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An infant with multiple congenital anomalies was found at autopsy to have a porencencephalic defect on the ventral surface of the left frontal lobe. The intracranial defect was seen in association with an anomalous configuration of the circle of Willis. The zone of tissue destruction corresponded to the vascular territory of the anterior choroidal and lenticulo-striate branches of the proximal middle cerebral arteries, which were absent on the left. The developmental anomaly of the circle of Willis may have predisposed to tissue destruction by compromising cerebral perfusion at midgestation, a stage of rapid brain growth.
    Type of Medium: Electronic Resource
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