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  • 1
    Electronic Resource
    Electronic Resource
    Increased excretion of harman by alcoholics depends on events of their life history and the state of the liver (1985)
    Springer
    Psychopharmacology 87 (1985), S. 64-68 
    Details
    ISSN: 1432-2072
    Keywords: Alcoholics ; Harman ; Trace amines ; β-carbolines ; Liver histology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Based on the hypothesis of a relationship between the concentration of trace amines like tetrahydroisoquinolines (TIQ's) and β-carbolines (BC's) in the brain and an increased voluntary ingestion of ethanol, the concentrations of ethanol, acetaldehyde and harman (a β-carboline) were examined in a group of 20 alcoholics. The patients excreted a higher amount of harman into the urine than non-alcoholics on the day of admission (harman-1) as well as at the end of the detoxication period, 14 days later (harman-14). Certain factors were related to the increased excretion of harman by alcoholics: The younger the patient when he/she consumed ethanol for the first time, the higher the concentration of acetaldehyde in the blood and the amount of harman (harman-14) excreted in the urine. Furthermore, the younger the patient when he/she was intoxicated with ethanol for the first time the higher the amount of harman (harman-14) in the urine. Patients with first grade relatives who were alcoholics excreted more harman (harman-14) than those without such relatives. The following variables were not related to harman-14: The average amount of ethanol consumed daily during the 6 months prior to admission, the presence of signs of intoxication and symptoms of withdrawal at admission to hospital, and the consumption of other psychotropic substances. A negative correlation was found between the state of the liver, as assessed by liver histology and γ-glutamate transferase (γ-GT) levels, and the concentration of harman in the urine. Thus, some events in the patient's history as well as the state of the liver are important for the increased excretion of harman into urine of alcoholics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431780
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  • 2
    Electronic Resource
    Electronic Resource
    Ethanol induces an increase of harman in the brain and urine of rats (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 107-113 
    Details
    ISSN: 1432-1912
    Keywords: Ethanol ; Harman ; Rat brain ; Regional distribution ; Urine ; Withdrawal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Harman occurs in rat brain, with the highest concentration in the cerebellum and the lowest in the striatum. 2 g/kg ethanol were ineffective with respect to the concentration of harman in the brain whereas 5 g/kg ethanol caused a time-dependent increase in the cerebral cortex as well as the cerebellum. A toxic dose (8 g/kg) of ethanol elicited no change of harman in the brain 3 h following the application. The rise in the harman concentration in the brain did not correlate with the increase of acetaldehyde in the blood after treatment with ethanol suggesting that several mechanisms are involved in the changes of the levels of harman. In subchronic experiments rats were treated with ethanol over a period of 5 or 6 days. Harman increased in the brain whereby the effect seemed to be more pronounced in the cerebellum than in the cerebral cortex. The concentration tended to increase over time and reached control levels again during withdrawal. The time course of the excretion of harman into the urine was similar to that of the brain in that it increased continuously during the period of ethanol treatment and reached control levels again during with-drawal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00500903
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  • 3
    Electronic Resource
    Electronic Resource
    Die Dupinschen Zykliden im pseudoeuklidischen Raum (1997)
    Springer
    Journal of geometry 60 (1997), S. 146-159 
    Details
    ISSN: 1420-8997
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In the pseudoeuclidean space1 E 3 a surface Δ of degree 3 or 4 is calledDupin-cyclide if there exists a (pseudoeuclidean) torus Θ such that a (pseudoeuclidean) spherical inversion maps Θ upon Δ. If the axis of Θ is respectively space-like, isotropic or time-like Δ is calledDupin-r-,-l- or-z-cyclide. ADupin-cyclide Δ is the envelope of two families of spheres, the caustic surfaces of Δ degenerate in caustic curves and the lines of curvature of Δ constitute two (orthogonal) families of circles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01252224
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  • 4
    Electronic Resource
    Electronic Resource
    Über die Drehschwingungen von Kurbelwellen (1966)
    Springer
    Mathematische Annalen 165 (1966), S. 152-162 
    Details
    ISSN: 1432-1807
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01344010
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  • 5
    Electronic Resource
    Electronic Resource
    Computerunterstützte identifizierung basischer substanzen (1987)
    Springer
    International journal of legal medicine 98 (1987), S. 249-254 
    Details
    ISSN: 1437-1596
    Keywords: Computer, analytic toxicology ; Data management, identification ; Toxicology, computer-supported ; EDV, analytische Toxikologie ; Data-Management, Identifizierung unbekannter Fremdsubstanzen ; Toxikologie, Computereinsatz
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Möglichkeiten eines Personal-Computers mit installierter Datenbanksoftware in der chemisch-toxikologischen Analytik werden aufgezeigt. Es wird eine toxikologische Datenbank mit 370 basischen Wirkstoffen vorgestellt, die ohne Kenntnis einer höheren Programmiersprache erstellt wurde und als Grundlage für die Identifizierung dieser Wirkstoffe in der routinemäßigen Analytik mittels PC, DC and GC dient.
    Notes: Summary The potential applications of a personal computer with integrated database software in toxicologic analysis are discussed. A toxicologic database including 370 basic compounds, is presented that was built up without knowledge of a higher programming language and was used as a base for drug identification in normal analysis by PC, DC and GC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00201231
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  • 6
    Electronic Resource
    Electronic Resource
    The settlement and growth of Sertularia cupressina (Hydrozoa, Sertulariidae) in Langstone Harbour, Hampshire, UK (1991)
    Springer
    Hydrobiologia 216-217 (1991), S. 215-219 
    Details
    ISSN: 1573-5117
    Keywords: Hydrozoa ; Sertularia ; larval settlement ; growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Aspects of the life cycle of the hydroid Sertularia cupressina were monitored over a period of 2 y using settlement panels. The reproductive period, determined by the presence of acrocysts and larval settlement, was November to January. Recently settled hydroids were more abundant on horizontal upward facing surfaces than on horizontal downward facing or vertical surfaces. The spatial dispersal of settlers was random. S. cupressina was a conspicuous and persistent component of fouling communities developing on both upward facing and vertical panels over 2 y. Following settlement in winter 1979–80, hydrocauli reached their greatest height between November 1980 and April 1981, but fouling and breakage of stems occurred during spring 1981. Regeneration from the tips of broken stems and from hydrorhizae occurred in June and July 1981.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00026465
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  • 7
    Electronic Resource
    Electronic Resource
    Über die Bedeutung der mit Schiffsladungen in Deutschland eingeschleppten Spinnentiere (1953)
    Springer
    Journal of pest science 26 (1953), S. 97-105 
    Details
    ISSN: 1612-4766
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02005137
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