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  • 1
    Electronic Resource
    Electronic Resource
    Role of iron in oxidative stress in skeletal muscle atrophied by immobilization (1992)
    Springer
    Pflügers Archiv 421 (1992), S. 295-297 
    Details
    ISSN: 1432-2013
    Keywords: iron ; deferoxamine ; oxidative stress ; skeletal muscle ; atrophy ; immobilization ; lipid peroxidation ; glutathione
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To clarify the role of iron in oxidative stress in skeletal muscle atrophied by immobilization, we investigated the effect of deferoxamine — an iron-chelating agent. Deferoxamine, iron-saturated deferoxamine and double-distilled water (control) were administered subcutaneously from the 4th day after immobilization via osmotic pumps to male Wistar rats (14 weeks old), one ankle joint of which was immobilized in the extended position. After 12 days' immobilization, soleus — typical slow red muscles were collected from both hind limbs and their levels of thiobarbituric acidreactive substance (TBARS) and glutathione were measured. Deferoxamine suppressed the increase of TBARS and glutathione disulfide in atrophied muscle while iron-saturated deferoxamine did not, which strongly suggests that the iron-chelating action of deferoxamine suppressed the increased oxidative stress. This means that iron plays a very important role in increasing oxidative stress in atrophied muscle. In addition, deferoxamine decreased the degree of atrophy, an effect thought to be mediated by the suppression of oxidative stress.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00374844
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  • 2
    Electronic Resource
    Electronic Resource
    Cultural Issues in the Primary Care of South Asians (2000)
    Springer
    Journal of immigrant health 2 (2000), S. 89-96 
    Details
    ISSN: 1573-3629
    Keywords: cultural issues ; South Asians ; primary care ; doctor–patient interactions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One of the fastest growing immigrant groups in the United States is from the Indian subcontinent of South Asia. Included in this group are people from India, Sri Lanka, Bangladesh, and Pakistan. Although there is considerable heterogeneity within and between the populations of these countries, cultural similarities contribute to common challenges when South Asian immigrants are seen in primary care settings in the United States. This article describes aspects of the South Asian culture and of the acculturation process relevant to establishing rapport and providing competent biopsychosocial care to individuals and families from this region. We discuss the differing needs of recent immigrants, second-generation Americans from South Asia, and individuals temporarily in the United States for study or employment. We discuss linguistic and interpersonal style concerns in regard to the relationship between health care professionals and immigrant patients and use case material to illustrate cultural issues. We conclude with suggestions for culturally sensitive health care of South Asians.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009585918590
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    Paper (German National Licenses)
    Fulltext
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