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  • SAGE Publications  (6)
  • 1
    Online Resource
    Online Resource
    Advanced pneumonic type of lung adenocarcinoma: survival predictors and treatment efficacy of the tumor
    SAGE Publications ; 2020
    In:  Tumori Journal
    Details
    In: Tumori Journal, SAGE Publications
    Abstract: To retrospectively explore the survival predictors and treatment efficacy of advanced pneumonic-type lung adenocarcinoma (P-ADC). Methods: Retrospective analysis of clinical data and survival follow-up was undertaken on 41 patients with advanced P-ADC from January 1, 2009, to April 30, 2019. Analysis on tumor biomarkers such as carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), and the cytokeratin-19-fragment (Cyfra21-1) were undertaken. The patients in this study were divided into three groups based on usage of tyrosine kinase inhibitor (TKI): TKI therapy group (including combination with chemotherapy), non-TKI therapy group (chemotherapy alone), and palliative care group. Results: More than half of the patients had higher levels of tumor biomarkers and the incidence of NSE was highest (81.8%), followed by CEA (74.4%) and Cyfra21-1 (74.1%). All patients had abnormal findings on chest computed tomography and with adenocarcinoma pathology. The overall survival (OS) time was 10.4 months in TKI group, 8.8 months in the non-TKI group, and 2.1 months in the palliative care group. Patients with higher level of serum Cyfra21-1 had insignificantly shorter survival time compared to those with normal Cyfra21-1 ( p = 0.067). TKI therapy and non-TKI therapy provided a better prognosis prediction compared to palliative care. TKI therapy improved prognosis compared to non-TKI therapy. The comprehensive based TKI therapy provided improved OS vs the non-TKI therapy. Conclusion: TKI-based therapy could improve the prognosis and OS for advanced P-ADC. This study recommends the analysis of EGFR mutations for all patients with advanced P-ADC.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/0300891620947159
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 280962-X
    detail.hit.zdb_id: 2267832-3
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Target enhancement and distractor inhibition affect transitory surround suppression in dual tasks using multiple rapid serial visual presentation streams
    SAGE Publications ; 2016
    In:  Quarterly Journal of Experimental Psychology Vol. 69, No. 9 ( 2016-09), p. 1777-1798
    Details
    In: Quarterly Journal of Experimental Psychology, SAGE Publications, Vol. 69, No. 9 ( 2016-09), p. 1777-1798
    Abstract: Few studies have investigated the interaction between temporal and spatial dimensions on selective attention using dual tasks in the multiple rapid serial visual presentation (RSVP) paradigm. A phenomenon that the surround suppression in space changes over time (termed transitory surround suppression, TSS, in the present study) has been observed, suggesting the existence of this time–space interaction. However, it is still unclear whether target enhancement or distractor inhibition modulates TSS. Four behavioural experiments were conducted to investigate the mechanism of TSS by manipulating the temporal lag and spatial distance factors between two targets embedded in six RSVP streams. The TSS effect was replicated in a study that eliminated confounds of perceptual effects and attentional switch (Experiment 1). However, the TSS disappeared when two targets shared the same colour in a between-subjects design (Experiment 2a) and a within-subject design (Experiment 2b), suggesting the impact of target enhancement on TSS. Moreover, the TSS was larger for within-category than for between-category distractors (Experiment 3), indicating the impact of distractor inhibition on TSS. These two influences on TSS under different processing demands of target and distractor processing were further confirmed in a skeletal design (Experiment 4). Overall, combinative effects of target enhancement and distractor suppression contribute to the mechanisms of time–space interaction in selective attention during visual search.
    Type of Medium: Online Resource
    ISSN: 1747-0218 , 1747-0226
    URL: Article
    DOI: 10.1080/17470218.2015.1099712
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2225936-3
    SSG: 5,2
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    Online Resource
  • 3
    Online Resource
    Online Resource
    New Developments in Multibody System Dynamics and Its Applications 2015
    SAGE Publications ; 2017
    In:  Advances in Mechanical Engineering Vol. 9, No. 3 ( 2017-03), p. 168781401769568-
    Details
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 9, No. 3 ( 2017-03), p. 168781401769568-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    URL: Article
    DOI: 10.1177/1687814017695685
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2501620-9
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  • 4
    Online Resource
    Online Resource
    A novel method for spacecraft electrical fault detection based on FCM clustering and WPSVM classification with PCA feature extraction
    SAGE Publications ; 2017
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 231, No. 1 ( 2017-01), p. 98-108
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 231, No. 1 ( 2017-01), p. 98-108
    Abstract: The measurement of spacecraft electrical characteristics and multi-label classification issues are generally including a large amount of unlabeled test data processing, high-dimensional feature redundancy, time-consumed computation, and identification of slow rate. In this paper, a fuzzy c-means offline (FCM) clustering algorithm and the approximate weighted proximal support vector machine (WPSVM) online recognition approach have been proposed to reduce the feature size and improve the speed of classification of electrical characteristics in the spacecraft. In addition, the main component analysis for the complex signals based on the principal component feature extraction is used for the feature selection process. The data capture contribution approach by using thresholds is furthermore applied to resolve the selection problem of the principal component analysis (PCA), which effectively guarantees the validity and consistency of the data. Experimental results indicate that the proposed approach in this paper can obtain better fault diagnosis results of the spacecraft electrical characteristics’ data, improve the accuracy of identification, and shorten the computing time with high efficiency.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    URL: Article
    DOI: 10.1177/0954410016638874
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2032759-6
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  • 5
    Online Resource
    Online Resource
    Preface
    SAGE Publications ; 2015
    In:  Advances in Mechanical Engineering Vol. 7, No. 9 ( 2015-09-01), p. 168781401560480-
    Details
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 7, No. 9 ( 2015-09-01), p. 168781401560480-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    URL: Article
    DOI: 10.1177/1687814015604802
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2501620-9
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  • 6
    Online Resource
    Online Resource
    Focal Organizing Pneumonia Mimicking Lung Cancer: A Surgeon's View
    SAGE Publications ; 2012
    In:  The American Surgeon Vol. 78, No. 1 ( 2012-01), p. 133-137
    Details
    In: The American Surgeon, SAGE Publications, Vol. 78, No. 1 ( 2012-01), p. 133-137
    Abstract: Focal organizing pneumonia is a unique form of organizing pneumonia. Little is known regarding its clinical and radiological feature, diagnosis, management, and outcome. Twenty patients with focal organizing pneumonia were investigated and compared with 40 patients with bronchogenic carcinoma. There were 38 men (63.3%) and 22 women (36.7%). The mean age was 55 ± 9.9 years. No specific feature in clinical and radiological manifestation was found to distinguish between focal organizing pneumonia and bronchogenic carcinoma. In patients with focal organizing pneumonia, wedge resection was performed in 12 cases and lobectomy in eight cases. Follow-up was complete with a median period of 26 months (range, 6 to 104 months). All patients were free from recurrence of organizing pneumonia. Clinical and radiologic findings of focal organizing pneumonia are nonspecific, and this unique form of organizing pneumonia is difficult to differentiate from lung cancer. Surgical resection allows both diagnosis and cure. However, considering the benign nature of this disease, major pulmonary resections should be avoided.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    URL: Article
    DOI: 10.1177/000313481207800150
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
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