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  • 1
    In: International Journal of Social Psychiatry, SAGE Publications, Vol. 66, No. 4 ( 2020-06), p. 361-372
    Kurzfassung: Recognizing the need for good quality, scientific and reliable information for strengthening mental health policies and programmes, the National Mental Health Survey (NMHS) of India was implemented by National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, in the year 2015–2016. Aim: To estimate the prevalence, socio-demographic correlates and treatment gap of mental morbidity in a representative population of India. Methods: NMHS was conducted across 12 Indian states where trained field investigators completed 34,802 interviews using tablet-assisted personal interviews. Eligible study subjects (18+ years) in households were selected by a multi-stage, stratified, random cluster sampling technique. Mental morbidity was assessed using MINI 6. Three-tier data monitoring system was adopted for quality assurance. Weighted and specific prevalence estimates were derived (current and lifetime) for different mental disorders. Mental morbidity was defined as those disorders as per the International Statistical Classification of Diseases, Tenth Revision Diagnostic Criteria for Research (ICD-10 DCR). Multivariate logistic regression was conducted to examine risk for mental morbidity by different socio-demographic factors. Survey was approved by central and state-level institutional ethical committees. Results: The weighted lifetime prevalence of ‘any mental morbidity’ was estimated at 13.67% (95% confidence interval (CI) = 13.61, 13.73) and current prevalence was 10.56% (95% CI = 10.51, 10.61). Mental and behavioural problems due to psychoactive substance use (F10–F19; 22.44%), mood disorders (F30–F39; 5.61%) and neurotic and stress-related disorders (F40–F48; 3.70%) were the most commonly prevalent mental morbidity in India. The overall prevalence was estimated to be higher among males, middle-aged individuals, in urban-metros, among less educated and in households with lower income. Treatment gap for overall mental morbidity was 84.5%. Conclusion: NMHS is the largest reported survey of mental morbidity in India. Survey estimated that nearly 150 million individuals suffer from one or the other mental morbidity in India. This information is to be used for planning, delivery and evaluating mental health programming in the country.
    Materialart: Online-Ressource
    ISSN: 0020-7640 , 1741-2854
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2020
    ZDB Id: 2066492-8
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
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    SAGE Publications ; 2014
    In:  Multiple Sclerosis Journal Vol. 20, No. 10 ( 2014-09), p. 1331-1341
    In: Multiple Sclerosis Journal, SAGE Publications, Vol. 20, No. 10 ( 2014-09), p. 1331-1341
    Kurzfassung: Neurodegeneration plays an important role in permanent disability in multiple sclerosis (MS). Objective: The objective of this paper is to determine whether progressive neurodegeneration occurs in MS eyes without clinically evident inflammation. Methods: Retinal nerve fiver layer thickness (RNFLT) and ganglion cell-inner plexiform layer thickness (GCIPT) were measured using Cirrus optical coherence tomography (OCT) in 133 relapsing–remitting MS (RRMS) patients (149 non-optic neuritis (ON), 97 ON eyes, last ON ≥6 months). Ninety-three patients were scanned at two visits. Percentages of abnormal GCIPT vs RNFLT ( 〈 5% of machine norms) in cross-sectional data were compared. Relations between RNFLT/GCIPT and MS duration (cross-sectional) and follow-up time (longitudinal) were assessed. Results: GCIPT was abnormal in more eyes than RNFLT (27% vs 16% p = 0.004 in non-ON, 82% vs 72% p = 0.007 in ON). RNFLT and GCIPT decreased with MS duration by −0.49 µm/yr ( p = 0.0001) and −0.36 ( p = 0.005) for non-ON; −0.52 ( p = 0.003) and −0.41 ( p = 0.007) for ON. RNFLT and GCIPT decreased with follow-up time by −1.49 µm/yr ( p 〈 0.0001) and −0.53 ( p = 0.004) for non-ON, −1.27 ( p = 0.002) and −0.49 ( p = 0.04) for ON. Conclusions: In RRMS eyes without clinically evident inflammation, progressive loss of RNFLT and GCIPT occurred, supporting the need for neuroprotection in addition to suppression of autoimmune responses and inflammation.
    Materialart: Online-Ressource
    ISSN: 1352-4585 , 1477-0970
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2014
    ZDB Id: 2008225-3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
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    SAGE Publications ; 2019
    In:  Vision: The Journal of Business Perspective Vol. 23, No. 1 ( 2019-03), p. 12-21
    In: Vision: The Journal of Business Perspective, SAGE Publications, Vol. 23, No. 1 ( 2019-03), p. 12-21
    Kurzfassung: Information technology (IT) industry in India has been facing a systemic issue of high attrition in the past few years, resulting in monetary and knowledge-based loses to the companies. The aim of this research is to develop a model to predict employee attrition and provide the organizations opportunities to address any issue and improve retention. Predictive model was developed based on supervised machine learning algorithm, support vector machine (SVM). Archival employee data (consisting of 22 input features) were collected from Human Resource databases of three IT companies in India, including their employment status (response variable) at the time of collection. Accuracy results from the confusion matrix for the SVM model showed that the model has an accuracy of 85 per cent. Also, results show that the model performs better in predicting who will leave the firm as compared to predicting who will not leave the company.
    Materialart: Online-Ressource
    ISSN: 0972-2629 , 2249-5304
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2019
    ZDB Id: 2220768-5
    SSG: 3,2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
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    SAGE Publications ; 2019
    In:  Natural Product Communications Vol. 14, No. 1 ( 2019-01), p. 1934578X1901400-
    In: Natural Product Communications, SAGE Publications, Vol. 14, No. 1 ( 2019-01), p. 1934578X1901400-
    Kurzfassung: A simple and highly efficient first stereoselective total synthesis of a benzofused macrocyclic lactone, ( 3S,7R)-de- O-methylbotryosphaeriodiplodin has been accomplished utilizing Jacobson's kinetic resolution, Marouka asymmetric allylation, Stille coupling, and ring-closing metathesis (RCM) reactions as key steps.
    Materialart: Online-Ressource
    ISSN: 1934-578X , 1555-9475
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2019
    ZDB Id: 2430442-6
    SSG: 15,3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
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    SAGE Publications ; 2017
    In:  Indian Journal of Gender Studies Vol. 24, No. 2 ( 2017-06), p. 217-230
    In: Indian Journal of Gender Studies, SAGE Publications, Vol. 24, No. 2 ( 2017-06), p. 217-230
    Kurzfassung: With the stage always associated with social reform and collective commitment, drama played an active role in the early-20th-century Kerala reform movement. These plays of the 1920s and the 1930s emphasised the need for reforming the situation of women. Produced as a part of social renovation, they had a strong ideology that stood in favour of gender equity and initiated a cross-fertilisation of theatre literature and social restructuring. This paper locates the impact of drama in 20th-century Kerala on the portrayal of Namboodiri women and purports to analyse the deconstructing waves that lashed through the medium of theatre against the conventional norms of feminine subjugation. In this regard, the study explores the role of selected plays by V. T. Bhattathiripad, M. R. Bhattathiripad, Premji and Lalithambika Anterjanam as critical tools in the social reformation.
    Materialart: Online-Ressource
    ISSN: 0971-5215 , 0973-0672
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2017
    ZDB Id: 2211914-0
    SSG: 6,24
    SSG: 3,4
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
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    SAGE Publications ; 2017
    In:  Indian Journal of Psychological Medicine Vol. 39, No. 4 ( 2017-07), p. 495-499
    In: Indian Journal of Psychological Medicine, SAGE Publications, Vol. 39, No. 4 ( 2017-07), p. 495-499
    Materialart: Online-Ressource
    ISSN: 0253-7176 , 0975-1564
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2017
    ZDB Id: 2622378-8
    SSG: 5,2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
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    SAGE Publications ; 2017
    In:  Indian Journal of Psychological Medicine Vol. 39, No. 2 ( 2017-03), p. 191-193
    In: Indian Journal of Psychological Medicine, SAGE Publications, Vol. 39, No. 2 ( 2017-03), p. 191-193
    Materialart: Online-Ressource
    ISSN: 0253-7176 , 0975-1564
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2017
    ZDB Id: 2622378-8
    SSG: 5,2
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
    In: Nutrition and Health, SAGE Publications, Vol. 26, No. 4 ( 2020-12), p. 323-346
    Kurzfassung: The World Health Organization recommends exclusive breastfeeding for every newborn during the first 6 months of life, yet women come across various challenges to continuing it. Aim: This systematic review was intended to identify barriers to exclusive breastfeeding among mothers. Methods: MEDLINE, Cumulative Index to Nursing and Allied health literature, ProQuest, Web of Science and Scopus databases were searched from January 1990 to October 2017. The systematic review included quantitative, qualitative and mixed-methods studies to identify barriers to exclusive breastfeeding among mothers of reproductive age with an infant aged between 0 and 12 months. All studies were screened based on titles, abstracts and full text by two reviewers independently. The methodological quality of included studies was assessed using appropriate tools. Of the 9737 eligible records, 44 studies were included for analysis. Classification of barriers to exclusive breastfeeding was adopted from the conceptual framework of factors affecting breastfeeding practices given by Hector and colleagues. Results: In total 32 barriers were grouped under individual, group and society level factors. Meta-analysis indicated that mothers who smoked had 2.49 times more odds of not exclusively breastfeeding than non-smoking mothers and mothers who had undergone caesarean section had 1.69 times more risk of cessation of exclusive breastfeeding than mothers who have had a vaginal childbirth. Conclusion: The systematic review revealed a complex interplay of various barriers related to exclusive breastfeeding. It is recommended that context-specific strategies should be designed in accordance with barriers existing in a region or country.
    Materialart: Online-Ressource
    ISSN: 0260-1060 , 2047-945X
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2020
    ZDB Id: 2647106-1
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
    Online-Ressource
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    SAGE Publications ; 2015
    In:  Natural Product Communications Vol. 10, No. 7 ( 2015-07), p. 1934578X1501000-
    In: Natural Product Communications, SAGE Publications, Vol. 10, No. 7 ( 2015-07), p. 1934578X1501000-
    Kurzfassung: Leishmaniasis is a neglected tropical disease caused by Leishmania parasitic protozoa, which currently lacks efficient treatment. Natural products have shown promise as a potential source for antiprotozoal drugs. This work focuses on the antileishmanial potential of Sassafras albidum (Lauraceae) bark extract. The crude bark extract of S. albidum showed excellent antileishmanial activity with an IC 50 value less than 12.5 μg/mL against promastigotes of L. amazonensis. The chloroform stem bark extract of S. albidum was subjected to preparative column chromatography. Five compounds were isolated, purified by recrystallization, and identified as sesamin, spinescin, β-sitosterol, hexatriacontanal, and 1-triacontanol. Antileishmanial and cytotoxic screening were performed on these compounds. Sesamin exhibited the best activity against L. amazonensis with an IC 50 of 15.8 μg/mL and was not cytotoxic to mouse macrophage cells ( CC 50 〉 100 μg/mL).
    Materialart: Online-Ressource
    ISSN: 1934-578X , 1555-9475
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2015
    ZDB Id: 2430442-6
    SSG: 15,3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 10
    In: Indian Journal of Psychological Medicine, SAGE Publications, Vol. 46, No. 1 ( 2024-01), p. 39-45
    Kurzfassung: Among the Indian adolescents, the prevalence of psychiatric morbidity and alcohol use disorders (AUD) are 7.3% and 1.3%. However, no separate data are available for indigenous tribal populations. This study estimated the prevalence of psychiatric morbidity and AUD and associated socio-demographic factors among adolescents in the tribal communities in three widely varying states in India. Methods: Using validated Indian versions of the MINI 6.0, MINI Kid 6.0, and ICD-10 criteria, we conducted a cross-sectional survey from January to May 2019 in three Indian sites: Valsad, Gujarat (western India); Nilgiris, Tamil Nadu (south India); and East Khasi Hills district of Meghalaya (north-east India) on 623 indigenous tribal adolescents. Results: Aggregate prevalence of any psychiatric morbidity was 15.9% (95% CI: 13.1–19.0) (males: 13.6%, 95% CI: 10.0–18.1; females: 17.9%, 95% CI: 13.9–22.6), with site-wise statistically significant differences: Gujarat: 23.8% (95% CI: 18.1–30.2), Meghalaya: 17.1% (95% CI: 12.4–22.7), Tamil Nadu: 6.2% (95% CI: 3.2–10.5). The prevalence of diagnostic groups was mood disorders 6.4% ( n = 40), neurotic- and stress-related disorders 9.1% ( n = 57), phobic anxiety disorder 6.3% ( n = 39), AUD 2.7% ( n = 17), behavioral and emotional disorders 2.7% ( n = 17), and obsessive-compulsive disorder 2.2% ( n = 14). These differed across the sites. Conclusion: The prevalence of psychiatric morbidity in adolescent tribals is approximately twice the national average. The most common psychiatric morbidities reported are mood (affective) disorders, neurotic- and stress-related disorders, phobic anxiety disorder, AUD, behavioral and emotional disorders, andobsessive-compulsive disorder.
    Materialart: Online-Ressource
    ISSN: 0253-7176 , 0975-1564
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2024
    ZDB Id: 2622378-8
    SSG: 5,2
    Standort Signatur Einschränkungen Verfügbarkeit
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