GLORIA

GEOMAR Library Ocean Research Information Access

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    MDPI AG ; 2019
    In:  Remote Sensing Vol. 11, No. 12 ( 2019-06-19), p. 1452-
    In: Remote Sensing, MDPI AG, Vol. 11, No. 12 ( 2019-06-19), p. 1452-
    Abstract: Himalayan glaciers have shrunk rapidly in recent decades, but the spatial pattern of ice loss is highly variable and appears to be modulated by factors relating to individual glacier characteristics. This hinders our ability to predict their future evolution, which is vital for water resource management. The aim of this study is to assess recent glacier changes in the little-studied Annapurna Conservation Area (ACA; area: 7629 km2) in Nepal, and to explore local controls influencing their behaviour. We map changes in glacier area, surface elevation, and ice flow velocity on a large sample of glaciers (n = 162) in the ACA between 2000 and 2016. We found that total glacier area decreased by 8.5% between 2000 and 2014/15. Ice surface velocity changes between 2002 and 2016 were variable, with no clear trend of acceleration or deceleration. The mean surface elevation change for a smaller sample of glaciers (n = 72) was −0.33 ± 0.22 m a−1 between 2000 and 2013/16, which equates to a mean mass balance of −0.28 ± 0.24 m w.e. a−1. There was a trend of increasingly less negative mass balance towards the north. Glaciers that lost the most mass in the north of the ACA tended to have lower maximum elevations, bottom-heavy hypsometries, and were more likely to be avalanche-fed. However, these patterns were not apparent in glaciers in central ACA. There was no significant difference in the mean surface elevation change rate on the ablation zones of debris-covered compared with debris-free glaciers. Our work shows that glaciers in the ACA are losing area and mass at variable rates, but that the influence of local controls is complex, which introduces large uncertainties when predicting their future evolution.
    Type of Medium: Online Resource
    ISSN: 2072-4292
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2513863-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    In: Viruses, MDPI AG, Vol. 15, No. 2 ( 2023-02-14), p. 530-
    Abstract: New variants of SARS-CoV-2 continue to emerge and evade immunity. We isolated SARS-CoV-2 temporally across the pandemic starting with the first emergence of the virus in the western hemisphere and evaluated the immune escape among variants. A clinic-to-lab viral isolation and characterization pipeline was established to rapidly isolate, sequence, and characterize SARS-CoV-2 variants. A virus neutralization assay was applied to quantitate humoral immunity from infection and/or vaccination. A panel of novel monoclonal antibodies was evaluated for antiviral efficacy. We directly compared all variants, showing that convalescence greater than 5 months post-symptom onset from ancestral virus provides little protection against SARS-CoV-2 variants. Vaccination enhances immunity against viral variants, except for Omicron BA.1, while a three-dose vaccine regimen provides over 50-fold enhanced protection against Omicron BA.1 compared to a two-dose. A novel Mab neutralizes Omicron BA.1 and BA.2 variants better than the clinically approved Mabs, although neither can neutralize Omicron BA.4 or BA.5. Thus, the need remains for continued vaccination-booster efforts, with innovation for vaccine and Mab improvement for broadly neutralizing activity. The usefulness of specific Mab applications links with the window of clinical opportunity when a cognate viral variant is present in the infected population.
    Type of Medium: Online Resource
    ISSN: 1999-4915
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2516098-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...