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  • Hindawi Limited  (41)
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  • 1
    Online Resource
    Online Resource
    A Typical Basalt Platform Landslide: Mechanism and Stability Prediction of Xiashan Landslide
    Hindawi Limited ; 2021
    In:  Advances in Civil Engineering Vol. 2021 ( 2021-4-2), p. 1-14
    Details
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2021 ( 2021-4-2), p. 1-14
    Abstract: The Xiashan landslide, which is classified as a typical basalt platform landslide, is the most massive landslide in Zhejiang Province, China. Once sliding occurs, it will pose a severe threat to the life and property of downstream residents and the nearby section of Hangzhou-Taizhou Expressway. On the basis of the geological conditions, present situation, and latest monitoring data of the landslide, this study finds that rainfall is the main influencing factor, and the creep mode is the main prediction mode of its subsequent deformation. The rainfall statistics of the landslide area in the past 30 years show that the rainfall and rainfall frequency in the landslide area display an increasing trend. The probability of heavy rain with rainfall intensity of 100–250 mm/day in the landslide area is very high. On this basis, combined with the numerical analysis method, a finite element model of the slope considering rainfall and groundwater conditions is constructed to analyze the causes and failure mechanism of this landslide comprehensively. Results indicate that the maximum tensile stress at the top of the trailing edge under the natural state is 5.10 MPa, which is very close to the saturated tensile strength of rock mass. Thus, tensile cracks are easily generated and developed, thereby causing the failure mode to be the hydraulic driving type. Also, with the increase in rainfall intensity, the slope plastic strain increases and the slope plastic zone develops and extends until it is completely penetrated. When the rainfall intensity is more than 200 mm/day, the slope safety factor is close to unity, and the slope approaches a failure condition. Therefore, the landslide should be controlled through water treatment and integrated with engineering measures.
    Type of Medium: Online Resource
    ISSN: 1687-8094 , 1687-8086
    URL: Article
    DOI: 10.1155/2021/6697040
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2449760-5
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  • 2
    Online Resource
    Online Resource
    The Prognostic Value of Serum Apolipoprotein A-I Level and Neutrophil-to-Lymphocyte Ratio in Colorectal Cancer Liver Metastasis
    Hindawi Limited ; 2022
    In:  Journal of Oncology Vol. 2022 ( 2022-9-27), p. 1-13
    Details
    In: Journal of Oncology, Hindawi Limited, Vol. 2022 ( 2022-9-27), p. 1-13
    Abstract: Background. Colorectal cancer liver metastasis (CRLM) is a high degree of malignancy with rapid disease progression and has a poor prognosis. Both serum apolipoprotein A-I (ApoA-I) and neutrophil-to-lymphocyte ratio (NLR) play key roles in anti-inflammation and antitumor. This study is aimed at evaluating the implication of serum ApoA-I level in combination with NLR in the prognosis of CRLM. Methods. We retrospectively analyzed the serum ApoA-I level and NLR in 237 patients with CRLM. Cox regression analyses were used to identify the independent prognostic significance of these indicators. Kaplan-Meier method and Log-rank test were applied to compute overall survival (OS). Both the ApoA-I and NLR were divided into three levels, according to their medians. A risk-stratified prediction model was established to evaluate the prognosis of patients with CRLM. The ROC curve AUC values were applied to evaluate the capability of the model. Results. Higher levels of ApoA-I and lower NLR were strongly associated with prolonged OS (Log-rank test, P 〈 0.05 ). The patients were then grouped into three queues according to the ApoA-I level and NLR. There was a crucial diversity in the OS ( P 〈 0.001 ) between the high-risk ( ApoA − I ≤ 1.03  g/L and NLR 〉 3.24 ), medium-risk ( ApoA − I 〉 1.03   g/L or NLR ≤ 3.24 ) and low-risk groups ( ApoA − I 〉 1.03   g/L and NLR ≤ 3.24 ). The AUC value of the prediction model ( AUC = 0.623 , 95% CI: 0.557-0.639, P = 0.001 ) was higher than other individual indicators (including ApoA-I, NLR, cT classification, and cN classification). Additionally, the association of the prediction model and cTN classification ( AUC = 0.715 , 95% CI: 0.606-0.708, P 〈 0.001 ) was better than the model and cTN classification alone. Conclusion. The combination of ApoA-I level and NLR could be a prognostic indicator for CRLM.
    Type of Medium: Online Resource
    ISSN: 1687-8469 , 1687-8450
    URL: Article
    DOI: 10.1155/2022/9149788
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2461349-6
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  • 3
    Online Resource
    Online Resource
    Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome–Wide Association Study
    Hindawi Limited ; 2018
    In:  Journal of Oncology Vol. 2018 ( 2018-12-18), p. 1-18
    Details
    In: Journal of Oncology, Hindawi Limited, Vol. 2018 ( 2018-12-18), p. 1-18
    Abstract: NM23 expression is closely associated with hepatocellular carcinoma (HCC) recurrence, but the hereditary factors influencing NM23 levels are unknown. Using public database, the diagnostic value of NM23 in HCC was investigated. A total of 424 hepatitis B virus- (HBV-) related HCC patients were enrolled to perform a genome–wide association study for identifying candidate variants associated with NM23 expression level. Additionally, a logistic regression model, haplotypes, and survival analysis were performed in the subsequent analysis. We identified high NM23 expression levels that have a diagnostic accuracy in HCC tissues and had a poor recurrence-free survival in HBV-related HCC patients. Variants near Psoriasis susceptibility 1 candidate 1 ( PSORS1C1 ) and StAR related lipid transdomain containing 3 ( STARD3 ) are associated with NM23 expression. The PSORS1C1 haplotype TGCACA and the STARD3 haplotype GG have favorable cumulative effects on NM23 expression. Further, variants in PSORS1C1 were associated with either overall survival (rs556285588, rs3095301, and rs3131003) only or overall survival and recurrence-free survival (rs560052000 and rs541820233) both in HCC patients. Our findings suggested that variants at the PSORS1C1 and STARD3 loci play an important role in NM23 regulation. Moreover, variants in PSORS1C1 are potential biomarkers for the prediction of postoperative clinical outcomes in HBV-related HCC patients. Thus, variants in PSORS1C1 and STARD3 are associated with NM23 expression and clinical outcomes of HBV-related HCC patients, which may be regarded as potential biomarkers for this disease.
    Type of Medium: Online Resource
    ISSN: 1687-8450 , 1687-8469
    URL: Article
    DOI: 10.1155/2018/6594169
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2018
    detail.hit.zdb_id: 2461349-6
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  • 4
    Online Resource
    Online Resource
    Evolution of the PB1 gene of human influenza A (H3N2) viruses circulating between 1968 and 2019
    Hindawi Limited ; 2022
    In:  Transboundary and Emerging Diseases Vol. 69, No. 4 ( 2022-07), p. 1824-1836
    Details
    In: Transboundary and Emerging Diseases, Hindawi Limited, Vol. 69, No. 4 ( 2022-07), p. 1824-1836
    Type of Medium: Online Resource
    ISSN: 1865-1674 , 1865-1682
    URL: Issue
    URL: Article
    DOI: 10.1111/tbed.v69.4
    DOI: 10.1111/tbed.14161
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2414822-2
    SSG: 22
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  • 5
    Online Resource
    Online Resource
    Truck-Lifting Prevention System Based on Vision Tracking for Container-Lifting Operation
    Hindawi Limited ; 2021
    In:  Journal of Advanced Transportation Vol. 2021 ( 2021-12-1), p. 1-9
    Details
    In: Journal of Advanced Transportation, Hindawi Limited, Vol. 2021 ( 2021-12-1), p. 1-9
    Abstract: Truck-lifting accidents are common in container-lifting operations. Previously, the operation sites are needed to arrange workers for observation and guidance. However, with the development of automated equipment in container terminals, an automated accident detection method is required to replace manual workers. Considering the development of vision detection and tracking algorithms, this study designed a vision-based truck-lifting prevention system. This system uses a camera to detect and track the movement of the truck wheel hub during the operation to determine whether the truck chassis is being lifted. The hardware device of this system is easy to install and has good versatility for most container-lifting equipment. The accident detection algorithm combines convolutional neural network detection, traditional image processing, and a multitarget tracking algorithm to calculate the displacement and posture information of the truck during the operation. The experiments show that the measurement accuracy of this system reaches 52 mm, and it can effectively distinguish the trajectories of different wheel hubs, meeting the requirements for detecting lifting accidents.
    Type of Medium: Online Resource
    ISSN: 2042-3195 , 0197-6729
    URL: Article
    DOI: 10.1155/2021/9612480
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2553327-7
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  • 6
    Online Resource
    Online Resource
    Design of diatomite-based hydrated salt composites with low supercooling degree and enhanced heat transfer for thermal energy storage
    Hindawi Limited ; 2019
    In:  International Journal of Energy Research Vol. 43, No. 13 ( 2019-10-25), p. 7058-7074
    Details
    In: International Journal of Energy Research, Hindawi Limited, Vol. 43, No. 13 ( 2019-10-25), p. 7058-7074
    Type of Medium: Online Resource
    ISSN: 0363-907X
    URL: Issue
    URL: Article
    DOI: 10.1002/er.v43.13
    DOI: 10.1002/er.4725
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 1480879-1
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  • 7
    Online Resource
    Online Resource
    Automatic Implementation of Fuzzy Reasoning Spiking Neural P Systems for Diagnosing Faults in Complex Power Systems
    Hindawi Limited ; 2019
    In:  Complexity Vol. 2019 ( 2019-06-19), p. 1-16
    Details
    In: Complexity, Hindawi Limited, Vol. 2019 ( 2019-06-19), p. 1-16
    Abstract: As an important variant of membrane computing models, fuzzy reasoning spiking neural P systems (FRSN P systems) were introduced to build a link between P systems and fault diagnosis applications. An FRSN P system offers an intuitive illustration based on a strictly mathematical expression, a good fault-tolerant capacity, a good description for the relationships between protective devices and faults, and an understandable diagnosis model-building process. However, the implementation of FRSN P systems is still at a manual process, which is a time-consuming and hard labor work, especially impossible to perform on large-scale complex power systems. This manual process seriously limits the use of FRSN P systems to diagnose faults in large-scale complex power systems and has always been a challenging and ongoing task for many years. In this work we develop an automatic implementation method for automatically fulfilling the hard task, named membrane computing fault diagnosis (MCFD) method. This is a very significant attempt in the development of FRSN P systems and even of the membrane computing applications. MCFD is realized by automating input and output, and diagnosis processes consists of network topology analysis, suspicious fault component analysis, construction of FRSN P systems for suspicious fault components, and fuzzy inference. Also, the feasibility of the FRSN P system is verified on the IEEE14, IEEE 39, and IEEE 118 node systems.
    Type of Medium: Online Resource
    ISSN: 1076-2787 , 1099-0526
    URL: Article
    DOI: 10.1155/2019/2635714
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2019
    detail.hit.zdb_id: 2004607-8
    SSG: 11
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  • 8
    Online Resource
    Online Resource
    Integrated Treatment Technology of Storage-Mining Inclined Goaf under Expressway
    Hindawi Limited ; 2020
    In:  Advances in Civil Engineering Vol. 2020 ( 2020-11-28), p. 1-19
    Details
    In: Advances in Civil Engineering, Hindawi Limited, Vol. 2020 ( 2020-11-28), p. 1-19
    Abstract: An inclined goaf caused by storage mining is a serious risk to subgrades and pavements. In this paper, effective investigation and detection methods of goafs were discussed considering the project of the Urumqi East Ring Expressway crossing the existing goaf of Zhongxing no. 2 mine. Moreover, by theoretical analysis and a series of field comparative tests, reasonable grouting parameters and the treatment plan were obtained. By comparing the test results of the field and laboratory, the influence of groundwater on the effect of grouting was revealed to reduce the compressive strength of the consolidating objects of the slurry. The high-density resistivity method presented strong anti-interference ability and high accuracy in a depth range of less than 150 m in the investigation of the goaf. The results of the treatment showed that it is necessary to conduct research and analysis from multiple aspects to obtain the best treatment plan of a goaf and ensure the safety of a project.
    Type of Medium: Online Resource
    ISSN: 1687-8094 , 1687-8086
    URL: Article
    DOI: 10.1155/2020/8822964
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2449760-5
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  • 9
    Online Resource
    Online Resource
    Actuator Fault Diagnosis for Discrete-Time Systems via Augmenting State Approach
    Hindawi Limited ; 2021
    In:  Mathematical Problems in Engineering Vol. 2021 ( 2021-5-24), p. 1-12
    Details
    In: Mathematical Problems in Engineering, Hindawi Limited, Vol. 2021 ( 2021-5-24), p. 1-12
    Abstract: For the problem of the actuator fault diagnosis in the control systems, this paper presents a novel method by using an interval estimation approach to detect the faults and reconstruct them. In order to make estimations of the unavoidable measurement noise, a descriptor system form is built. Firstly, a full-order interval observer is developed to detect actuator faults for its sensitiveness to them. Then, a reduced-order one, which is robust to actuator faults, is presented. This method does not need the boundary information of faults; thus, the design condition is more relaxed. In order to make the interval observer stable and cooperative, linear matrix inequalities and a time-varying transformation are employed to ensure the error system matrix to be Schur and nonnegative. Based on the interval estimation results of the aforementioned method, an interval reconstruction method of actuator faults is proposed. Finally, results of the two simulation examples verify the proposed methods are effective and accurate.
    Type of Medium: Online Resource
    ISSN: 1563-5147 , 1024-123X
    URL: Article
    DOI: 10.1155/2021/5565353
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2014442-8
    SSG: 11
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  • 10
    Online Resource
    Online Resource
    Age-Related Changes in Nucleus Pulposus Mesenchymal Stem Cells: An In Vitro Study in Rats
    Hindawi Limited ; 2017
    In:  Stem Cells International Vol. 2017 ( 2017), p. 1-13
    Details
    In: Stem Cells International, Hindawi Limited, Vol. 2017 ( 2017), p. 1-13
    Abstract: The functions of mesenchymal stem cells (MSCs) appear to decline with age due to cellular senescence, which could reduce the efficacy of MSCs-based therapies. Recently, MSCs have been identified in the nucleus pulposus, which offers great potential for intervertebral disc (IVD) repair. However, this potential might be affected by the senescence of nucleus pulposus MSCs (NPMSCs), but whether or not this exists remains unknown. The aim of this study was to investigate the age-related changes in NPMSCs. NPMSCs isolated from young (3-month-old) and old (14-month-old) Sprague-Dawley rats were cultured in vitro. Differences in morphology, proliferation, colony formation, multilineage differentiation, cell cycle, and expression of β -galactosidase (SA- β -gal) and senescent markers (p53, p21, and p16) were compared between groups. Both young and old NPMSCs fulfilled the criteria for definition as MSCs. Moreover, young NPMSCs presented better proliferation, colony-forming, and multilineage differentiation capacities than old NPMSCs. Old NPMSCs displayed senescent features, including significantly increased G0/G1 phase arrest, increased SA- β -gal expression, decreased S phase entry, and significant p53-p21-pRB pathway activation. Therefore, this is the first study demonstrating that senescent NPMSCs accumulate in IVD with age. The efficacy of NPMSCs is compromised by donor age, which should be taken into consideration prior to clinical application.
    Type of Medium: Online Resource
    ISSN: 1687-966X , 1687-9678
    URL: Article
    DOI: 10.1155/2017/6761572
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2017
    detail.hit.zdb_id: 2573856-2
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