In:
Synlett, Georg Thieme Verlag KG, Vol. 33, No. 20 ( 2022-12), p. 2033-2037
Kurzfassung:
A practical method for synthesizing 7-azaserotonin and 7-azamelatonin was developed by using 3-bromo-5-methoxy-1-tosyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-ol as a starting material. This compound is a useful reactant for the formal C3-electrophilic reaction. The lactone derivative obtained by the reaction with Meldrum’s acid was used as a key intermediate, in which the C2 unit was introduced into the 7-azaindole skeleton.
Materialart:
Online-Ressource
ISSN:
0936-5214
,
1437-2096
DOI:
10.1055/s-0041-1738758
Sprache:
Englisch
Verlag:
Georg Thieme Verlag KG
Publikationsdatum:
2022
ZDB Id:
2042012-2
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