GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    Online-Ressource
    Online-Ressource
    Cambridge :Cambridge University Press,
    Schlagwort(e): Geophysics--Fluid models. ; Electronic books.
    Beschreibung / Inhaltsverzeichnis: Geophysical fluid dynamics illustrates the rich interplay between mathematical analysis, nonlinear dynamics, statistical theories, qualitative models and numerical simulations. This self-contained introduction will suit a multi-disciplinary audience ranging from beginning graduate students to senior researchers. It is the first book following this approach and contains many recent ideas and results.
    Materialart: Online-Ressource
    Seiten: 1 online resource (565 pages)
    Ausgabe: 1st ed.
    ISBN: 9780511167584
    DDC: 550
    Sprache: Englisch
    Anmerkung: Cover -- Half-title -- Title -- Copyright -- Contents -- Preface -- 1 Barotropic geophysical flows and two-dimensional fluid flows: elementary introduction -- 1.1 Introduction -- 1.2 Some special exact solutions -- Fourier series tool kit -- 1.2.1 Exact solutions for the Euler equations -- 1.2.2 Exact solutions with beta-effect and generalized Kolmogorov forcing -- 1.2.3 Rossby waves -- 1.2.4 Topographic effect in steady states -- 1.2.5 A dynamical solution with beta-plane and layered topography -- 1.2.6 Beta-plane dynamics with large-scale shear flow -- A test problem for dissipative mechanisms -- 1.3 Conserved quantities -- 1.3.1 Conservation of energy -- Conservation of energy for periodic flows -- 1.3.2 Large-scale and small-scale flow interaction via topography -- 1.3.3 Infinite number of conserved quantities - generalized enstrophy -- 1.3.4 Several conserved quantities -- 1.3.5 Summary of conserved quantities: periodic geometry -- 1.4 Barotropic geophysical flows in a channel domain - an important physical model -- 1.4.1 The impulse and conserved quantities -- 1.4.2 Conservation of circulation -- 1.4.3 Summary of conserved quantities: channel geometry -- 1.5 Variational derivatives and an optimization principle for elementary geophysical solutions -- 1.5.1 Some important variational derivatives -- 1.5.2 An optimization principle for elementary geophysical solutions -- 1.6 More equations for geophysical flows -- 1.6.1 The models -- 1.6.2 Relationships between various models -- Derivation of the barotropic one-layer model from the continuously stratified model -- Derivation of the two-layer model from the continuously stratified model -- Derivation of the one- and one-half-layer model from the two-layer model -- Derivation of the barotropic quasi-geostrophic model from the F-plane model -- References -- 2 The response to large-scale forcing. , 2.1 Introduction -- A remarkable identity -- 2.2 Non-linear stability with Kolmogorov forcing -- 2.2.1 Non-linear stability in restricted sense -- 2.2.2 Finite-dimensional dynamics on the ground modes and non-linear stability -- Fourier representation for the dynamic equations -- 2.2.3 Counter-example of unstable ground state modes dynamics for truncated inviscid flows -- 2.3 Stability of flows with generalized Kolmogorov forcing -- References -- 3 The selective decay principle for basic geophysical flows -- 3.1 Introduction -- 3.2 Selective decay states and their invariance -- 3.3 Mathematical formulation of the selective decay principle -- The Rossby waves degenerate into generalized Taylor vortices in the absence of the geophysical beta-plane effect. -- 3.4 Energy-enstrophy decay -- 3.5 Bounds on the Dirichlet quotient, A (t) -- 3.6 Rigorous theory for selective decay -- 3.6.1 Convergence to an asymptotic state -- 3.6.2 Convergence to the selective decay state -- 3.6.3 Stability of the selective decay states -- 3.6.4 Underlying simplifying mechanisms -- 3.7 Numerical experiments demonstrating facets of selective decay -- 3.7.1 Measure of anisotropy -- 3.7.2 Explicit solutions of the sinh-Poisson equation -- 3.7.3 Numerical examples -- References -- Appendix 1 Stronger controls on A (t) -- Appendix 2 The proof of the mathematical form of the selective decay principle in the presence of the beta-plane effect -- 4 Non-linear stability of steady geophysical flows -- 4.1 Introduction -- 4.2 Stability of simple steady states -- 4.2.1 Non-linear stability and the energy method -- 4.2.2 Simple states with topography, but no mean flow or beta-effect -- 4.2.3 Simple states with topography, mean flow, and beta-effect -- 4.3 Stability for more general steady states -- 4.4 Non-linear stability of zonal flows on the beta-plane. , 4.5 Variational characterization of the steady states -- References -- 5 Topographic mean flow interaction, non-linear instability, and chaotic dynamics -- 5.1 Introduction -- 5.2 Systems with layered topography -- 5.2.1 Hamiltonian structure -- 5.3 Integrable behavior -- 5.3.1 The case h = 0 -- 5.3.2 The case Beta = 0 -- 5.3.3 Single mode topography -- 5.4 A limit regime with chaotic solutions -- 5.4.1 Single mode topography -- 5.4.2 Interaction of non-linear resonances -- 5.4.3 Two modes in the topography: a perturbative Melnikov analysis -- 5.5 Numerical experiments -- 5.5.1 Perturbation of single mode topography -- 5.5.2 Two-mode layered topography and topographic blocking events -- 5.5.3 Random perturbations with multi-mode topography -- 5.5.4 Symmetry breaking perturbations and topographic blocking events -- References -- Appendix 1 -- Appendix 2 -- 6 Introduction to information theory and empirical statistical theory -- 6.1 Introduction -- 6.2 Information theory and Shannon's entropy -- 6.3 Most probable states with prior distribution -- 6.4 Entropy for continuous measures on the line -- 6.4.1 Continuous measure on the line -- 6.4.2 Entropy and maximum entropy principle -- 6.4.3 Coarse graining and loss of information -- 6.4.4 Relative entropy as a "distance" function -- 6.4.5 Information theory and the finite-moment problem for probability measures -- 6.5 Maximum entropy principle for continuous fields -- 6.6.1 The Prior distribution -- 6.6.2 Constraints on the potential vorticity distribution -- 6.6.3 Statistical predictions of the maximum entropy principle -- 6.6.4 Determination of the multipliers and geophysical effect -- 6.7 Application of the maximum entropy principle to geophysical flows with topography and mean flow -- 6.7.1 One-point statistics for potential vorticity and large-scale mean velocity and Shannon entropy. , 6.7.2 The constraints on the one-point statistics -- 6.7.3 Maximum entropy principle and statistical prediction -- 6.7.4 Determination of the multipliers and geophysical effects -- References -- 7 Equilibrium statistical mechanics for systems of ordinary differential equations -- 7.1 Introduction -- 7.2 Introduction to statistical mechanics for ODEs -- 7.2.1 The Liouville property -- 7.2.2 Evolution of probability measures and the Liouville equation -- 7.2.3 Conserved quantities and their ensemble averages -- 7.2.4 Shannon entropy and the maximum entropy principle -- 7.2.5 The most probable state and Gibbs measure -- 7.2.6 Ergodicity and time averaging -- 7.2.7 A simple example violating the Liouville property -- 7.3 Statistical mechanics for the truncated Burgers-Hopf equations -- 7.3.1 The truncated Burgers-Hopf systems and their conserved quantities -- 7.3.2 The Liouville property -- 7.3.3 The Gibbs measure and the prediction of equipartition of energy -- 7.3.4 Numerical evidence of the validity of the statistical theory -- 7.3.5 Truncated Burgers-Hopf equation as a model with statistical features in common with atmosphere -- A scaling theory for temporal correlations -- Numerical evidence for the correlation scaling theory -- 7.4 The Lorenz 96 model -- 7.4.1 Geophysical properties of the Lorenz 96 model -- Rossby waves -- 7.4.2 Equilibrium statistical theory for the undamped unforced L-96 model -- 7.4.3 Statistical properties of the damped forced and undamped unforced L96 models -- Rescaling the damped forced L96 model -- Linear stability of the mean state -- The bulk behavior of the rescaled problem -- The climatology of different forcing regimes in rescaled coordinates -- References -- 8 Statistical mechanics for the truncated quasi-geostrophic equations -- 8.1 Introduction -- 8.2 The finite-dimensional truncated quasi-geostrophic equations. , 8.2.1 The spectrally truncated quasi-geostrophic equations -- 8.2.2 Conserved quantities for the truncated system -- 8.2.3 Non-linear stability of some exact solutions the truncated system -- 8.2.4 The Liouville property -- 8.3 The statistical predictions for the truncated systems -- 8.4 Numerical evidence supporting the statistical prediction -- 8.5 The pseudo-energy and equilibrium statistical mechanics for fluctuations about the mean -- 8.6 The continuum limit -- 8.6.1 The case with a large-scale mean flow -- 8.6.2 The case without large-scale mean flow but with generic topography -- 8.6.3 The case with no geophysical effects -- 8.6.4 The case with no large-scale mean flow but with topography having degenerate spectrum -- High energy subcase -- 8.7 The role of statistically relevant and irrelevant conserved quantities -- References -- Appendix 1 -- 9 Empirical statistical theories for most probable states -- 9.1 Introduction -- 9.2 Empirical statistical theories with a few constraints -- 9.2.1 The energy-circulation empirical theory with a general prior distribution -- 9.2.2 The energy-circulation impulse theory with a general prior distribution -- 9.3 The mean field statistical theory for point vortices -- 9.3.1 Derivation of the mean field point-vortex theory from an empirical statistical theory -- 9.3.2 Complete statistical mechanics for point vortices -- The dynamics of point vortices in the plane -- Liouville property -- The mean field limit equations as N … -- 9.4 Empirical statistical theories with infinitely many constraints -- 9.4.1 Maximum entropy principle incorporating all generalized enstrophies -- 9.4.2 The most probable state and the mean field equation -- 9.5 Non-linear stability for the most probable mean fields -- References. , 10 Assessing the potential applicability of equilibrium statistical theories for geophysical flows: an overview.
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    Publikationsdatum: 2016-06-09
    Beschreibung: The purpose of this study was to compare the efficacy and tolerability of the Ahmed glaucoma valve (AGV) implant and the Baerveldt implant for the treatment of refractory glaucoma.
    Digitale ISSN: 1471-2415
    Thema: Medizin
    Publiziert von BioMed Central
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Publikationsdatum: 2015-07-04
    Beschreibung: Background: The purpose of this study was to examine the choroidal thickness of patients with high myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare them with healthy subjects. Methods: We first conducted a cross-sectional study and then performed a meta-analysis to address this issue further. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the macular choroidal thickness of high myopic eyes and normal control eyes were measured and compared at each location. Univariate and multivariate linear regression analyses were performed to assess the association between choroidal thickness and clinical factors such as axial length (AL), spherical equivalent (SE), and central corneal thickness. In the high myopic eyes, subgroup analysis of macular choroidal thickness was performed in eyes with or without lacquer cracks and choroidal neovascularization (CNV). The meta-analyses were conducted using the Stata software package. Results: The high myopic eyes had a thinner choroid than the control eyes at all macular locations (all P 
    Digitale ISSN: 1471-2415
    Thema: Medizin
    Publiziert von BioMed Central
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Publikationsdatum: 2015-04-30
    Beschreibung: Background: Hepatocyte carcinoma (HCC) is one of the most common malignancies worldwide. Despite many achievements in diagnosis and treatment, HCC mortality remains high due to the malignant nature of the disease. Novel approaches, especially for targeted therapy, are being extensively explored. Gene therapy is ideal for such purpose for its specific expression of exogenous genes in HCC cells driven by tissue-specific promoter. However strategies based on correction of mutations or altered expressions of genes responsible for the development/progression of HCC have limitations because these aberrant molecules are not presented in all cancerous cells. In the current work, we adopted a novel strategy by targeting the DNA replication step which is essential for proliferation of every cancer cell. Methods: A recombinant adenovirus with alpha fetoprotein (AFP) promoter-controlled expressions of artificial microRNAs targeting DNA polymerases α, δ, ε and recombinant active Caspase 3, namely Ad/AFP-Casp-AFP-amiR, was constructed. Results: The artificial microRNAs could efficiently inhibit the expression of the target polymerases in AFP-positive HCC cells at both RNA and protein levels, and HCC cells treated with the recombinant virus Ad/AFP-Casp-AFP-amiR exhibited significant G0/1 phase arrest. The proliferation of HCC cells were significantly inhibited by Ad/AFP-Casp-AFP-amiR with increased apoptosis. On the contrary, the recombinant adenovirus Ad/AFP-Casp-AFP-amiR did not inhibit the expression of DNA polymerases α, δ or ε in AFP-negative human normal liver cell HL7702, and showed no effect on the cell cycle progression, proliferation or apoptosis. Conclusions: Inhibition of DNA polymerases α, δ and ε by AFP promoter-driven artificial microRNAs may lead to effective growth arrest of AFP-positive HCC cells, which may represent a novel strategy for gene therapy by targeting the genes that are essential for the growth/proliferation of cancer cells, avoiding the limitations set by any of the individually altered gene.
    Digitale ISSN: 1471-2407
    Thema: Medizin
    Publiziert von BioMed Central
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    Publikationsdatum: 2015-03-25
    Beschreibung: Background: Necrosis of alveolar macrophages following Mycobacterium tuberculosis infection has been demonstrated to play a vital role in the pathogenesis of tuberculosis. Our previous study demonstrated that Wnt/β-catenin signaling was able to promote mycobacteria-infected cell apoptosis by a caspase-dependent pathway. However, the functionality of this signaling in the necrosis of macrophage following mycobacterial infection remains largely unknown. Methods: Murine macrophage RAW264.7 cells were infected with Bacillus Calmette-Guerin (BCG) in the presence of Wnt/β-catenin signaling. The necrotic cell death was determined by cytometric assay and electronic microscopy; the productions of reactive oxygen species (ROS) and reduced glutathione (GSH) were measured by a cytometric analysis and an enzyme-linked immunosorbent assay, respectively; and the activity of poly (ADP-ribose) polymerase 1 (PARP-1)/apoptosis inhibition factor (AIF) signaling was examined by an immunoblotting assay. Results: The BCG can induce RAW264.7 macrophage cells necrosis in a dose- and time-dependent manner along with an accumulation of reactive oxygen species (ROS). Intriguingly, an enhancement of Wnt/β-catenin signaling shows an ability to reduce the mycobacteria-induced macrophage necrosis. Mechanistically, the activation of Wnt/β-catenin signaling is capable of inhibiting the necrotic cell death in BCG-infected RAW264.7 cells through a mechanism by which the Wnt signaling scavenges intracellular ROS accumulation and increases cellular GSH concentration. In addition, immunoblotting analysis further reveals that Wnt/β-catenin signaling is capable of inhibiting the ROS-mediated cell necrosis in part through a PARP-1/AIF- dependent pathway. Conclusions: An activation of Wnt/β-catenin signaling can inhibit BCG-induced macrophage necrosis by increasing the production of GSH and scavenging ROS in part through a mechanism of repression of PARP-1/AIF signaling pathway. This finding may thus provide an insight into the underlying mechanism of alveolar macrophage cell death in response to mycobacterial infection.
    Digitale ISSN: 1471-2172
    Thema: Medizin
    Publiziert von BioMed Central
    Standort Signatur Einschränkungen Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...