Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Scandinavian journal of immunology
9 (1979), S. 0
ISSN:
1365-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Lymphocytes sensitized in mixed leucocyte culture (MLC) were restimulaied with non-T or complete cells. Cells primed against autologous non-T cells and restimulated with autologous cells gave responses with the kinetics of a secondary response. In contrast, cells primed against either type of autologous cell responded to restimulation by allogeneic cells with the kinetics of a primary MLC response. Following priming against alloantigens good secondary responses against both complete and non-T allogeneic restimulators were seen. Restimulation with auto-logous non-T colts, but not autologous complete cells, also led to secondary responses. The observation of” different responses to antigens expressed on non-T autologous lymphocytes, in comparison to complete cells, implies that the secondary MLC involves more than a response against alloantigen. Allogeneic and autologous MLC may he qualitatively different phenomena. the latter representing the recognition of identifying structure's between interacting populations of cooperating cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-3083.1979.tb03276.x
Permalink
|
Location |
Call Number |
Limitation |
Availability |
