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Note: Intro -- Note to the Reader -- Appendixes.

Note: Front Cover -- Quantitative Genetic Variation -- Copyright Page -- Table of Contents -- Contributors -- Preface -- Acknowledgments -- PART I - INTRODUCTION TO THE STUDY OF QUANTITATIVE GENETIC VARIATION -- CHAPTER 1. INTRODUCTION -- REFERENCES -- CHAPTER 2. HISTORICAL OVERVIEW: QUANTITATIVE VARIATION AND POLYGENIC SYSTEMS -- I. THE GENETICAL INTERPRETATION -- II. ESTABLISHING THE INTERPRETATION -- III. CHROMOSOMES AND QUANTITATIVE VARIATION -- IV. BIOMETRICAL GENETICS -- V. THE NUMBER OF GENES: DIRECT ESTIMATES -- VI. BIOMETRICAL ESTIMATES: EFFECTIVE FACTORS -- VII. GENE ACTION -- VIII. THE GENIC STRUCTURES INVOLVED -- IX. THE IMPACT OF SELECTION -- X. ORGANISATION OF POLYGENIC SYSTEMS -- REFERENCES -- CHAPTER 3. QUANTITATIVE GENETIC VARIATION IN FUNGI -- I. INTRODUCTION -- II. ANALYSIS OF QUANTITATIVE GENETIC VARIATION IN FUNGI -- III. SELECTION -- IV. THE NATURE OF POLYGENIC SYSTEMS -- V. PHYSIOLOGICAL COMPONENTS OF QUANTITATIVE VARIATION -- VI. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 4. POLYGENIC VARIATION IN NATURAL POPULATIONS OF DROSOPHILA -- I. INTRODUCTION -- II. RESISTANCE TO CLIMATE-RELATED ENVIRONMENTAL EXTREMES -- III. RESOURCE UTILIZATION AND ALCOHOL -- IV. AGING AMONG ISOFEMALE STRAINS WITH RESPECT TO ENVIRONMENT -- V. DISCUSSION -- VI. SUMMARY -- ACKNOWLEDGMENTS -- REFERENCES -- PART II - THE BIOMETRICAL APPROACH TO QUANTITATIVE VARIATION -- CHAPTER 5. THE BIOMETRICAL APPROACH TO QUANTITATIVE VARIATION -- I. INTRODUCTION -- II. SOURCES OF VARIATION -- III. SCALING TESTS -- IV. STATISTICS, PARAMETERS, AND MODELS -- V. MODEL FITTING -- VI. INTERPRETATION -- VII. EXPERIMENTAL DESIGN -- VIII. APPLICATIONS -- IX. CONCLUSIONS -- REFERENCES -- PART III - THE USES AND LIMITATIONS OF SELECTION -- CHAPTER 6. AN OVERVIEW OF SELECTION THEORY AND ANALYSIS -- I. INTRODUCTION -- II. SELECTION AND VARIABILITY. , III. SELECTION PATTERNS -- IV. DIRECTIONAL SELECTION -- V. CORRELATED RESPONSES AND SELECTION LIMIT -- VI. STABILIZING SELECTION -- VII. DISRUPTIVE SELECTION -- REFERENCES -- CHAPTER 7. COMPUTER SIMULATIONS -- I. INTRODUCTION -- II. PERFORMANCE OF SIMULATIONS -- III. INCORPORATION OF BIOLOGICAL FACTS -- IV. RESULTS OF SIMULATION STUDIES -- V. SELECTION AND TARGET VARIABLES -- VI. CONTRIBUTIONS OF SIMULATION STUDIES IN QUANTITATIVE GENETICS -- REFERENCES -- CHAPTER 8. CANALISATION AND SELECTION -- I. THE CANALISED CHARACTER -- II. MEASUREMENT OF CANALISATION -- III. THE CANALISING PHENOTYPE -- IV. MECHANISM OF CANALISATION -- V. SELECTION IN SCUTE AND SELECTION IN WILD-TYPE -- VI. THE EFFECT OF SELECTING IN WILD-TYPE ON SCUTE POPULATIONS -- VII. REDUCTION OF CANALISATION AS A RESULT OF SELECTION IN WILD-TYPE -- VIII. WHAT IS IT THAT IS BEING CANALISED? -- IX. DOSAGE COMPENSATION AND SELECTION -- X. CONCLUSIONS -- REFERENCES -- CHAPTER 9. THE POSTERIOR CROSSVEIN IN DROSOPHILA AS A MODEL PHENOTYPE -- I. INTRODUCTION -- II. DESCRIPTION AND CAUSALITY OF CROSSVEIN DEFECTS -- III. A QUANTITATIVE MODEL -- IV. THE SOURCES OF VARIATION -- V. POLYGENIC CVE STRAINS -- VI. APPLICATIONS -- VII. A POSTSCRIPT ON GENETIC ASSIMILATION -- VIII. A BRIEF REVIEW OF STUDIES ON THE POSTERIOR CROSSVEIN -- REFERENCES -- PART IV - ANALYSIS OF INDIVIDUAL GENE EFFECTS -- CHAPTER 10. POLYGENIC MUTATION -- I. INTRODUCTION -- II. METHODS AND EXAMPLES FOR THE ESTIMATION OF POLYGENIC MUTATION RATES -- III. GENERAL REVIEW OF THE EXPERIMENTAL RESULTS -- IV. DISCUSSION -- REFERENCES -- CHAPTER 11. USES OF RECOMBINANT INBRED LINES -- I. AN HISTORICAL OVERVIEW OF RI STRAINS IN RELATION TO TISSUE TRANSPLANTATION -- II. POSSIBLE APPLICATIONS OF RI STRAINS TO QUANTITATIVE GENETIC ANALYSES -- III. APPLICATION OF RI STRAINS TO THE ANALYSIS OF DIFFERENT PHENOTYPES. , IV. BEHAVIOR GENETIC ANALYSES -- V. USES AND LIMITATIONS OF RI STRAINS -- ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 12. POLYGENE MAPPING: USES AND LIMITATIONS -- I. INTRODUCTION -- II. FIRST EXAMPLE -- III. SECOND EXAMPLE -- IV. MORE COMPLEX PROBLEMS -- V. EFFECTIVE FACTORS AND LOCATED POLYGENES OR QUANTITATIVE TRAIT LOCI -- REFERENCES -- CHAPTER 13. COMPUTER SIMULATION OF THE BREEDING PROGRAM FOR POLYGENE LOCATION -- I. INTRODUCTION -- II. COMPUTER SIMULATION OF A BREEDING PROGRAM -- III. RESULTS AND FUTURE APPLICATIONS -- ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 14. POLYGENIC INFLUENCES UPON DEVELOPMENT IN A MODEL CHARACTER -- I. INTRODUCTION -- II. DEVELOPMENTAL QUESTIONS AND THE CHOICE OF A MODEL EXPERIMENTAL SYSTEM -- III. RESPONSE TO SELECTION -- IV. THE NATURE AND NUMBER OF POLYGENES -- V. QUANTITATIVE VARIATION AS A COMPLEMENT TO MOSAIC ANALYSIS IN DEVELOPMENTAL GENETICS -- ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 15. GENES AFFECTING QUANTITATIVE ASPECTS OF PHYSIOLOGY IN RODENTS -- I. INTRODUCTION -- II. PHENOTYPIC REFINEMENT -- III. CONTROL OF GENETIC DIVERSITY -- IV. IMPORTANCE OF POST - SEGREGATIONAL STUDIES -- V. PROSPECTS -- REFERENCES -- CHAPTER 16. CYTOLOGICAL MARKERS AND QUANTITATIVE VARIATION IN WHEAT -- I. ANEUPLOIDS AND THE CHROMOSOME CLASSIFICATION OF WHEAT -- II. THE USE OF ANEUPLOIDS IN GENETIC ANALYSIS -- III. THE APPLICATION OF THESE METHODS TO THE STUDY OF EAREMERGENCE TIME IN WHEAT -- IV. ENVIRONMENT AND GENETICAL ANALYSIS -- V. CHARACTER ANALYSIS AND THE GENETICS OF SEMI-DWARFISM IN WHEAT -- VI. PLEIOTROPIC EFFECTS OF GENES IDENTIFIED BY GENETICAL AND CHARACTER ANALYSES -- VII. CONCLUSIONS -- REFERENCES -- CHAPTER 17. SYNTHESIS: POLYGENIC VARIATION IN PERSPECTIVE -- REFERENCES -- INDEX.

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