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  • 1975-1979  (3)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Thymus rudiment of the athymic nude mouse (1975)
    [s.l.] : Nature Publishing Group
    Nature 256 (1975), S. 491-493 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 The lymphoepithelial rudiment of a nu/nu (BALB/c) male aged 122 d. H & E, x 160. Fig. 2 Sensitivity of cells from euthymic mouse thymus and nujnu lymphoepithelial rudiment (thymus?), spleen and lymph nodes to anti-6 antibodies. Solid columns, anti-6-C3H+ complement; hatched columns, C ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/256491a0
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Experimental immune complex glomerulopathy: Immunomorphological aspects and correlations with human disease (1975)
    Springer
    International urology and nephrology 7 (1975), S. 219-233 
    Details
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirteen rabbits received parenteral injections of human serum albumin (HSA) in regular doses and intervals during 6–32 weeks. The antigen load elicited immune responses of variable degree, giving a good correlation with the extent and quality of immune complex (IMC) deposition, as shown by immunological methods, electron and fluorescence microscopy and by histoautoradiography. Morphology of immune deposits (IMD) depended on the composition of the IMC and produced a continuous scale of glomerular involvement, ranging from minimal and focal to massive and diffuse deposition. Probable rudimentary traces of IMD were apparent in the ultrastructure even in animals with negative results of both immunological and immunfluorescence examinations. The relationships are discussed between experimental IMC-induced glomerulopathy on the one hand, and some problems of development and bioptic evaluation of human glomerulonephritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02082678
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Clinical detection of rejection nephropathy using125I-labelled fibrinogen (1976)
    Springer
    International urology and nephrology 8 (1976), S. 71-77 
    Details
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using a modified fibrinogen-uptake (FUT) test, 22 patients were investigated at various intervals after kidney transplantation. Eight of the patients had developed or showed early clinical signs of acute rejection crisis at the time of measurement. Another fourteen patients formed the control group with no evidence of florid rejection process. Comparison of the125I-fibrinogen accumulation in the renal grafts between the two mentioned groups showed clear differences with high statistical significance (p〈0.001). Uptake of labelled fibrinogen was increased in every acute rejection transplant. Histologically the kidneys with increased accumulation of fibrinogen showed extensive deposits of fibrin in blood vessels, glomeruli, intracapillary thrombi and in the interstitium. Except for the limitations discussed in this paper we consider this test to be of a great clinical value in the diagnosis of rejection episodes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02081994
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    Paper (German National Licenses)
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