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  • 1995-1999  (134)
  • 1985-1989  (71)
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Year
  • 1
    Online Resource
    Online Resource
    New York, NY :Springer,
    Keywords: Heart-Diseases-Molecular aspects. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (334 pages)
    Edition: 1st ed.
    ISBN: 9781461312895
    Series Statement: Developments in Molecular and Cellular Biochemistry Series ; v.19
    DDC: 612.1/73
    Language: English
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  • 2
    Online Resource
    Online Resource
    New York, NY :Springer,
    Keywords: Heart-Molecular aspects. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (313 pages)
    Edition: 1st ed.
    ISBN: 9781461312796
    Series Statement: Developments in Molecular and Cellular Biochemistry Series ; v.18
    DDC: 612.173
    Language: English
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  • 3
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin / Heidelberg,
    Keywords: Chemical elements. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (289 pages)
    Edition: 8th ed.
    ISBN: 9783662075036
    Series Statement: Gmelin Handbook of Inorganic and Organometallic Chemistry - 8th Edition Series ; v.S-c... / C / 11 / a
    DDC: 540
    Language: English
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  • 4
    Online Resource
    Online Resource
    Berlin, Heidelberg : Springer Berlin Heidelberg
    Keywords: Mathematics ; Group theory ; Topological Groups ; Lie groups. ; Topological Groups, Lie Groups ; Group Theory and Generalizations ; Mathematics ; Determinantenring
    Description / Table of Contents: Determinantal rings and varieties have been a central topic of commutative algebra and algebraic geometry. Their study has attracted many prominent researchers and has motivated the creation of theories which may now be considered part of general commutative ring theory. The book gives a first coherent treatment of the structure of determinantal rings. The main approach is via the theory of algebras with straightening law. This approach suggest (and is simplified by) the simultaneous treatment of the Schubert subvarieties of Grassmannian. Other methods have not been neglected, however. Principal radical systems are discussed in detail, and one section is devoted to each of invariant and representation theory. While the book is primarily a research monograph, it serves also as a reference source and the reader requires only the basics of commutative algebra together with some supplementary material found in the appendix. The text may be useful for seminars following a course in commutative ring theory since a vast number of notions, results, and techniques can be illustrated significantly by applying them to determinantal rings
    Type of Medium: Online Resource
    Pages: Online-Ressource (VIII, 240 p, online resource)
    ISBN: 9783540392743 , 9783540194682
    Series Statement: Lecture Notes in Mathematics 1327
    RVK:
    Language: English
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  • 5
    Keywords: Forschungsbericht
    Type of Medium: Online Resource
    Pages: 19 p. = 96 kB, text and images
    Edition: [Electronic ed.]
    Language: German
    Note: Contract no. BMBF 03F0153A; 03FO153A , nIndex , Differences between the printed and electronic version of the document are possible
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 28 (1985), S. 89-91 
    ISSN: 1432-1041
    Keywords: atenolol ; pindolol ; sleep disturbance ; β-blockers ; dreaming ; fatigue ; hypertension ; lipophilicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary This randomized crossover out-patient study was designed to compare the antihypertensive effects of atenolol and pindolol. After a wash-out period of two weeks in pretreated cases, 107 patients with essential hypertension were given either atenolol 100 mg once-daily or pindolol 20 mg slow release (SR) once-daily. Both atenolol and pindolol lowered blood pressure over the 24 week period. The diastolic blood pressure reduction was significantly greater (p〈0.01) with atenolol than with pindolol. Before β-blocker therapy, many patients had already experienced side-effects such as fatigue, sleep disturbances and dreams. This probably relates to the high sensitivity of the analogue scale used to assess side-effects, and to the high incidence of such symptoms in untreated patients. As the study progressed there was a reduction in the frequency of fatigue (p〈0.03) and dreams (p〈0.05) in both groups, whereas sleep disturbances significantly increased under pindolol (p〈0.05) but decreased under atenolol (p〈0.05). The only important side-effect difference between the two β-blockers was the higher incidence of sleep disturbances with pindolol which may be due to the higher lipophilicity of this β-blocker.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 63 (1985), S. 361-363 
    ISSN: 1432-1440
    Keywords: Primary aldosteronism ; Captopril ; Spironolactone ; Renin-angiotensin ; Converting-enzyme ; Secondary hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In three patients with primary aldosteronism, the acute effect of a single dose of captopril on the elevated mean arterial blood pressure (MAP) was studied before and after 4 weeks of treatment with spironolactone. Before spironolactone therapy, captopril did not cause any drop in MAP. Four weeks later, after an oral daily dose of 400 mg spironolactone, MAP was still elevated in all three patients, though electrolyte abnormalities were fully corrected. Since plasma renin activity (PRA) was increased to values above the normal range, the acute effect of captopril on MAP was tested again. A single dose of 25 mg captopril then caused a fall in MAP to normal. These data reveal the conversion from a renin-independent to a renindependent kind of hypertension after spironolactone therapy in three patients with primary aldosteronism syndrome. This might be of pathogenetic and therapeutic interest.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 64 (1986), S. 327-332 
    ISSN: 1432-1440
    Keywords: Severe hypertension ; Minoxidil ; Captopril
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The antihypertensive efficacy of minoxidil and captopril was compared in 23 males with essential or renal parenchymatous hypertension refractory to conventional antihypertensive drug therapy. Following a pretreatment period the patients were randomly assigned to receive either minoxidil, 2.5 mg twice daily (n=12), or captopril, 25 mg twice daily (n=11). In patients with diastolic blood pressure 〉95 mmHg, doses of minoxidil and captopril were increased in 2-week intervals. Patients who maintained diastolic pressure 〉95 mmHg and/or those with intolerable side effects were switched over to the alternative substance. After a mean observation period of 12 weeks a significant decrease in systolic and diastolic blood pressure was observed (179/114 vs 148/92 mmHg in the minoxidil group; 176/111 vs 158/97 mmHg in the captopril group). The primary response rate was 75% in patients treated with minoxidil and 55% in those with captopril (not significant). After the change to the alternative substance two of the four non-responders on captopril and one of the two non-responders on minoxidil became responders. Side effects occurred significantly more often during minoxidil than captopril (p〈0.05). The high efficacy of minoxidil and captopril in the treatment of severe hypertension refractory to conventional drugs was confirmed. Minoxidil lowered blood pressure slightly more than captopril, but it had a higher incidence of side effects than captopril.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 65 (1987), S. 428-432 
    ISSN: 1432-1440
    Keywords: Rare cause of primary aldosteronism ; Hypokalemic hypertension ; Diagnostic procedure ; Treatment of malignant adrenal disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 58-year-old white woman with hypertension and severe hypokalemia was found to have a carcinoma of the left adrenal gland. Plasma renin activity was constantly under the normal limit, while plasma aldosterone levels were pathologically elevated. Plasma cortisol (8:00 a.m.) and excretion rates of urinary free cortisol were within the normal range. After an adrenalectomy, relapsing excessive aldosterone secretion was successfully treated with opDDD (Lysodrene). Ten months after the diagnosis was established, the patient died from a bleeding liver metastasis.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 107 (1997), S. 2930-2941 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The ground-state potential energy surface (PES) for linear arrangements of the N2H+ molecular ion is numerically computed by the multireference single- and double-excitation configuration interaction (MRD-CI) technique. An analytical representation of the potential energy function is obtained by fitting a power series in the Simons–Parr–Finlan coordinates to the numerical data. For investigating the intramolecular dynamics we describe the nuclear motion by a Gaussian wave packet located initially in the strong interaction region of the PES. The vibrational eigenvalue spectrum is calculated by Fourier transforming the time autocorrelation function. The spectrum is then analyzed statistically in the light of random matrix theory (RMT) to understand the nature of the intramolecular dynamics. We examine the short-range correlation in the spectrum through the nearest neighbor level spacing distribution P(s) and the long-range correlation through Δ3 and Σ2 statistics. The spectrum in the time domain is analyzed by computing the ensemble averaged survival probability 〈〈P(t)〉〉. The above four quantities obtained from the spectrum are compared with the distribution predicted for regular, irregular, and mixed (intermediate) spectra by the RMT. We find the system is of mixed type and the fractional irregularity is 0.7±0.05. In order to reveal a possible correspondence to the classical dynamics, we have carried out the spectral analysis of the dynamical variables for classical trajectories over a wide range of internal energies. In addition the classical dynamics of proton collisions with N2 molecules has also been preliminarily studied on the same PES, in particular the dependence of the final vibrational action nf on the initial vibrational phase φi of N2 and, furthermore, the Poincaré surface-of-section superimposed with the zero-order separatrix; we find a large number of trapped trajectories. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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