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  • 2000-2004  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Role Of Calcitonin Gene-Related Peptide In Ischaemic Preconditioning In Diabetic Rat Hearts (2001)
    Melbourne, Australia : Blackwell Science Pty
    Clinical and experimental pharmacology and physiology 28 (2001), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. It has been suggested that calcitonin gene-related peptide (CGRP) is involved in the protection provided by ischaemic preconditioning in rat hearts and that ischaemic preconditioning is absent in diabetic rat hearts.2. In the present study, we tested the relationship between sensory nerve function and ischaemic preconditioning in diabetic rats.3. In 4- and 8-week diabetic rats and age-matched non- diabetic controls, 30 min global ischaemia and 40 min reperfusion caused a significant decrease in cardiac function and a marked increase in creatine kinase (CK) release. Ischaemic preconditioning, by three cycles of 5 min ischaemia and 5 min reperfusion, improved the recovery of cardiac function and decreased CK release during reperfusion in 4-week diabetic rat hearts. However, the cardioprotection afforded by ischaemic preconditioning was lost in 8-week diabetic rat hearts. Pretreatment with CGRP for 5 min also significantly improved the recovery of cardiac function and decreased CK release in rats subjected to 4 or 8 weeks of diabetes.4. The content of CGRP in the coronary effluent during ischaemic preconditioning was significantly increased in 4-week diabetic rat hearts (P 〈 0.05). However, only a slight increase in the release of CGRP was shown in 8-week diabetic rat hearts (P 〉 0.05).5. In summary, the present results suggest that the protection afforded by ischaemic preconditioning is attenuated in diabetic rats and that the change may be related to the reduction in CGRP release in diabetic rat hearts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1440-1681.2001.03467.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of biodegradability by the reduction of Tetrazolium Violet in Biolog microplates (2000)
    Springer
    Biotechnology letters 22 (2000), S. 909-913 
    Details
    ISSN: 1573-6776
    Keywords: biodegradability ; biodegradation test ; Biolog microplates ; ozonation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A novel biodegradation test using Biolog MT microplates was developed. The method was based on the reduction of Tetrazolium Violet during mineralization of organic substrates. Both a microbial mixed culture (activated sludge) and pure culture of a bacterium (Pseudomonas aeruginosa) were used as inocula to evaluate its applicability. The procedure was successfully demonstrated with the ozonated samples of p-nitrophenol. Compared with previous methods, the proposed method is fast and convenient to use in practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005608113423
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    Paper (German National Licenses)
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