In:
Zeitschrift für Naturforschung C, Walter de Gruyter GmbH, Vol. 58, No. 11-12 ( 2003-12-1), p. 833-836
Abstract:
The clastogenic effect of total dichloromethane, methanol and water extracts, four bioactive fractions and three individual constituents from Carthamus lanatus aerial parts were evaluated in mice by bone marrow chromosome aberration assay with mitomycin C as positive control. Significant differences in the percentage of aberrant mitosis of the extracts were observed. The dichloromethane extract exhibited a considerable clastogenic effect and the water extract a negligible one. Different types of chromosome aberrations and time-dependant effects for the active fractions and individual compounds were found.
Type of Medium:
Online Resource
ISSN:
1865-7125
,
0939-5075
DOI:
10.1515/znc-2003-11-1216
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2003
detail.hit.zdb_id:
2078107-6
SSG:
12
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