Publication Date:
2012-12-01
Description:
EMBO Reports 13, 1087 (2012). doi:10.1038/embor.2012.164 Authors: Julia Mössinger, Marnix Wieffer, Eberhard Krause, Christian Freund, Fabian Gerth, Michael Krauss & Volker Haucke Phosphatidylinositol (PI) 4-phosphate (PI(4)P) and its metabolizing enzymes serve important functions in cell signalling and membrane traffic. PI 4-kinase type IIα (PI4KIIα) regulates Wnt signalling, endosomal sorting of signalling receptors, and promotes adaptor protein recruitment to endosomes and the trans-Golgi network. Here we identify the
Keywords:
phosphatidylinositol 4-kinase type IIαE3 ubiquitin ligaseItchendosomesWnt signalling
Print ISSN:
1469-221X
Electronic ISSN:
1469-3178
Topics:
Biology
,
Medicine
Permalink