GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 65 (1987), S. 428-432 
    ISSN: 1432-1440
    Keywords: Rare cause of primary aldosteronism ; Hypokalemic hypertension ; Diagnostic procedure ; Treatment of malignant adrenal disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 58-year-old white woman with hypertension and severe hypokalemia was found to have a carcinoma of the left adrenal gland. Plasma renin activity was constantly under the normal limit, while plasma aldosterone levels were pathologically elevated. Plasma cortisol (8:00 a.m.) and excretion rates of urinary free cortisol were within the normal range. After an adrenalectomy, relapsing excessive aldosterone secretion was successfully treated with opDDD (Lysodrene). Ten months after the diagnosis was established, the patient died from a bleeding liver metastasis.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical prospecting 35 (1987), S. 0 
    ISSN: 1365-2478
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Physics
    Notes: Since the important contributions of Dürbaum and Dix, 30 years ago, velocity profile estimation procedures on horizontally layered and vertically heterogeneous media from seismic probing data have been based largely on hyperbolic moveout models and RMS and stacking velocity concepts. Re-examination of the fundamentals reveals that quantitative velocity heterogeneity and canonical valocity profiles have been implicit factors for moveout modelling and for profile inversion in the use of the Dix procedure. Heterogeneity h is the ratio (and vRMS the geometric or harmonic mean) of the path-average and time-average velocities for a raypath or, in a more restricted sense, for the normal ray belonging to a velocity profile. The canonical profile for a given velocity profile or profile segment is a moveout-equivalent monotonically increasing ramp-like profile.The ramp or constant gradient in depth is the simplest velocity profile approximator which can explicitly accommodate velocity heterogeneity. A ramp model structure is detailed which facilitates moveout simulation and model parameter estimation, and the parametric effects are explored. The horizontal offset range is quantified for which this model can give good moveout approximations.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 58 (1987), S. 363-368 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A setup for pulse radiolysis experiments is described consisting of the following main components: an array of 15 photomultipliers attached to a spectrograph (allowing 4032 spectra to be recorded with a time resolution of 500 ns per spectrum), self-regulating high-voltage supply for the photomultipliers, computer-controlled solution mixing and dispensing system, and provisions for continuous dose variation of the FEBETRON-accelerator electron beam. The general performance of the system is discussed and construction or electronic details are given for special components.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1435-1463
    Keywords: diazepam ; N-desmethyldiazepam ; endogenous benzodiazepine receptor ligand
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Benzodiazepine-binding inhibitory (BBI) activity was detected in aqueous extracts of brain and peripheral tissues of rats. The BBI activity in brain and in adrenals was, at least partially, due to the presence of N-des-methyldiazepam and diazepam as shown by HPLC, UV-spectroscopy and mass spectrometry. In addition, BBI activity was found in standardized rat food, as well as in a variety of cereals and in other nutritive plant products. In wheat grains diazepam and N-desmethyldiazepam could be identified by HPLC and analysis by gas chromatography combined with mass spectrometry. The estimated amounts of the two benzodiazepines present in rat brain and adrenals and in wheat grains were in the low ppb range. Since laboratory contamination was rigorously excluded we conclude that diazepam and N-desmethyldiazepam are naturally occurring compounds. These findings may explain their occurrence in the brain and adrenals of animals.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 65 (1987), S. 155-160 
    ISSN: 1432-1440
    Keywords: Hypertension ; Ca2+
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several disturbances of cellular Ca2+ metabolism have been described in essential hypertension and in the spontaneously hypertensive rat. Possibly the elevation of intracellular free Ca2+ concentration in arterial smooth muscle cells is one important step in the pathogenesis of primary hypertension. In most studies a decreased energy-dependent Ca2+ transport has been proposed as a mechanism. However, disturbances in cellular Ca2+ metabolism, which can be exclusively ascribed to essential hypertension, have not yet been found. The cause of altered cellular Ca2+ transport in primary hypertension may either be a genetically determined defect of membrane transport or a still-unidentified humoral factor.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of earth sciences 76 (1987), S. 233-243 
    ISSN: 1437-3262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract In the context of Gondwana North Victoria Land forms the Antarctic conjugate terrain to the East Australian Lachlan Fold Belt, where the distinction between S- and I-type granitoids was first worked out (Chappell &White 1974). Thus the area was considered a good testing ground for the hypothesis when the German Antarctic North Victoria Land Expedition (Ganovex) resumed fieldwork there in 1979/80. It was known at that time that there existed a Cambro/Ordovician and a Devonian/Carboniferous granitoid generation, which, in analogy to Australia, were taken to be related to two different orogenetic events. Our geological, petrographical and geochemical investigations, together with radiometric age dating, revealed that this is true only for the older granite generation. The younger generation is in fact anorogenic. At the same time, it became obvious that the S- and I-type classification did not completely fit the observed field data. At this pointPitcher's (1982) subdivision of the I-types into a »Cordilleran« and a »Caledonian« suite offered a solution to account for the observed irregularities. At about the same time, plate tectonic models based on evidence independent from the granite classification were developed for this part of the active Gondwana margin. This offers the opportunity to crosscheck the tectonic environment derived from the granite classification: The characteristics of the older, Cambro/Ordovician granitoids allow a perfect accommodation in the model of an active margin above a subduction zone as derived from other evidence. For the younger (Devonian/Carboniferous) granitoids, however, the postulated tectonic setting (post-collisional uplift and faulting) could not be verified in North Victoria Land. It is concluded thatPitchers classification is applicable in its petrographic and geochemical aspects but that the tectonic environment postulated for the production of »Caledonian« I-type granitoids may not be the same in all investigated areas.
    Abstract: Résumé Dans le contexte du Gondwana, la Terre Victoria est le pendant antarctique de la zone plissée de Lachlan, en Australie Orientale, où la distinction entre granites S et I a été établie pour la première fois (Chappel &White 1974). C'est pourquoi la vérification de cette hypothèse a été portée au programme de l'expédition allemande à la Terre Victoria en 1979–80 (Ganovex). On connaissait à cette époque l'existence d'une génération cambro-ordovicienne et d'une génération dévono-carbonifère de granitoÏdes qui, par analogie avec l'Australie, avaient été rapportées à deux événements orogéniques différents. Nos investigations géologiques, pétrologiques, géochimiques et géochronologiques montrent que cette conclusion n'est vraie que pour les granites de la première génération. La seconde génération est, en fait, anorogénique. Il s'est avéré en mÊme temps que la répartition en types S et I ne correspond pas exactement aux observations de terrain. Par contre, la distinction introduite parPitcher (1982) parmi les granites I entre une série »de Cordillère« et une série »Calédonienne« peut expliquer les irrégularités que nous observons. Environ à cette époque, des modèles géodynamiques basés sur des considérations indépendantes de la classification des granites ont été proposés pour cette partie de la marge active du Gondwana. Ces modèles permettent de recouper les considérations sur l'environnement tectonique des granites, déduites de leur classification: Les caractères des granitoÏdes anciens, cambro-ordoviciens, s'accordent parfaitement au modèle d'une marge active surmontant une subduction. Par contre, pour les granitoÏdes jeunes, dévono-carbonifères, la situation tectonique postulée (soulèvement et fracturation post-collision) n'a pas pu Être confirmée sur la Terre Victoria. En conclusion, la classification dePitcher est applicable dans ses aspects pétrographiques et géochimiques, mais l'environnement tectonique qui préside à la formation de granitoÏdes de type »Calédonien I« n'est pas nécessairement le mÊme dans toutes les régions étudiées.
    Notes: Zusammenfassung Im Gondwana Rahmen bildet Nord Victoria Land das antarktische Pendant zur ostaustralischen Lachlan Mobilzone, wo die Einteilung von Graniten in S- und I-Typen entwickelt wurde (Chappell &White 1974). Deshalb war eine überprüfung dieser neu entwickelten Hypothese eines der Arbeitsziele, als die deutschen Nord Victoria Land Expeditionen (Ganovex) dort 1979 ihre Arbeiten aufnahmen. An den bekannten zwei Granitgenerationen der Region wurden geologische, petrographische und geochemische Untersuchungen sowie Altersbestimmungen durchgeführt, deren Ergebnisse sich folgenderma\en zusammenfassen lassen. Die ältere, kambro-ordovizische Granitfolge steht, analog zur Situation in Australien, in enger Beziehung zu einer bedeutenden Orogenese, während sich zur jüngeren, devonisch-karbonischen Suite kein zugehöriges tektonisches Ereignis finden lie\. Dies steht im Gegensatz zur Situation in Australien/Tasmanien. Die S- und I-Typ Klassifikation, auf Nord Victoria Land angewendet, weist ähnliche Widersprüche auf, wie siePitcher (1982) zur Aufteilung der I-Typen in »kordillere« und »kaledonische« Sippen führten. Plattentektonische Modelle, die in den letzten Jahren für diese Region am mobilen Rand Gondwanas unabhängig von der Granitklassifikation nach geologischen und tektonischen Kriterien entwickelt wurden, erlauben es, die vonPitcher entwickelten tektonischen Bildungsmilieus für verschiedene Granit-Typen zu überprüfen: Die Charakteristiken der älteren (kambro-ordovizischen) Granite erlauben ein widerspruchsloses Einfügen in das aus anderen Kriterien abgeleitete Bild eines aktiven Kontinentalrandes über einer Subduktionszone. Für die jüngeren (devonisch-karbonischen) Granite dagegen, die im Charakter den »kaledonischen« I-TypenPitchers entsprechen, sind die für deren Bildung postulierten Vorgänge, nämlich Hebung und Dehnung nach einer Kollision, in Nord Victoria Land nicht erkennbar. Demnach erscheint zwar die KlassifikationPitchers sinnvoll, da sie in ihrer petrographisch-geochemischen Charakterisierung nachvollziehbar ist, aber das abgeleitete tektonische Milieu für die Bildung der »kaledonischen« Typen bedarf einer weiteren überprüfung.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Diabetologia 30 (1987), S. 100-103 
    ISSN: 1432-0428
    Keywords: Fetal rats ; skeletal growth ; streptozotocin ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary For largely unknown reasons severe or moderate diabetes of pregnant rats results in pronounced fetal growth retardation. Therefore, some skeletal growth parameters of fetal rats from streptozotocin diabetic mothers were studied in vivo and in vitro. Two days post conception rats were intravenously injected with 65 mg/kg body weight streptozotocin. On day 20 post conception 8 normal and 8 diabetic rat mothers received 5 μCi 3-H thymidine intraperitoneally. One day later the experiments were terminated. Fetal body weight and body length were significantly (p〈0.05–0.001) reduced in the hyperglycaemic rats compared to normal rats, as was the thymidine incorporation into rib cartilage (p〈0.02). In the cell culture colony formation from isolated chondrocytes of normal and hyperglycaemic fetuses was determined. Proinsulin, insulin (62.5–250 ng/ml), insulin-like growth factor I and II (6.25–25 ng/ml) significantly (p〈0.05–0.001) augmented colony formation in a dose-dependent manner, with the somatomedins being 8 times more effective than proinsulin or insulin. Isolated chondrocytes from hyperglycaemic compared to normal fetuses formed significantly (p〈0.05–0.001) fewer colonies in the basal state and in response to all 4 hormones. The results confirm the growth retardation of fetuses from diabetic rat mothers. A reduced responsiveness of chondrocytes from hyperglycaemic fetuses to various growth factors could be demonstrated as compared to cells from normal fetuses.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 242 (1987), S. 629-630 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We compared the efficacy of ceftazidime and cefazolin in combination with tobramycin in the treatment of lower respiratory tract infections. Bacterial pathogens were isolated from sputum or bronchial secretions from 92 patients. The clinical results were identical in both groups: All patients showed an improvement of the clinical symptoms or were cured. 88% of the patients in the ceftazidime-group and 76% of the patients in the cefazolin/tobramycin-group showed an eradication of the pathogens without superinfection. This difference was not statistically significant (p=0.095). Monotherapy with ceftazidime was clinically and bacteriologically as effective as a combination therapy with cefazolin and tobramycin.
    Notes: Zusammenfassung In der vorliegenden Studie vergleichen wir die Wirksamkeit einer antibiotischen Therapie mit Ceftazidim mit der einer Kombinationstherapie (Cefazolin und Tobramycin) bei Patienten mit entzündlichen Erkrankungen der tiefen Atemwege. Ausgewertet wurden 92 Patienten, bei denen ein Keimnachweis im Sputum oder Bronchialsekret gelang. Die klinischen Ergebnisse waren in beiden Gruppen identisch. Alle Patienten zeigten eine Besserung der Symptomatik bzw. waren geheilt. Eine Keimelimination ohne Superinfektion gelang bei 88% der Patienten der Ceftazidim-Gruppe und bei 76% der Patienten in der Cefazolin/Tobramycin-Gruppe. Diese Unterschiede waren statistisch nicht signifikant (p=0,095). Bei entzündlichen Erkrankungen der tiefen Atemwege ist eine Monotherapie mit Ceftazidim klinisch und bakteriologisch ebenso wirksam wie eine Kombinationstherapie mit Cefazolin und Tobramycin.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...