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  • 1
    ISSN: 1432-1459
    Keywords: Mitochondrial myopathy ; Ragged-red fibres ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An immunohistochemical method is reported using the M-II68 monoclonal antibody, which detects mitochondrial accumulations (“ragged-red fibres”) in routinely processed (formalin-fixed, paraffin-embedded) muscle tissue. Ten cases with electron-microscopically and histochemically proven mitochondrial myopathy featured 4% to 24% ragged-red fibres. In a series of 50 muscle biopsies without mitochondrial myopathy, scattered ragged-red fibres (〈0.1%) were present in a few normal and pathological muscles. The immunohistochemical method is specific for mitochondria, does not require frozen tissue and permits rapid examination of large areas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-808X
    Keywords: Schlüsselwörter Tubare Sterilität ; IVF ; Reaktivierte Tuberkulose ; Meningoencephalitis ; Key words Tubal infertility ; IVF ; Reactivated tuberculosis ; Meningoencephalitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The simultaneous occurrence of a pregnancy after in-vitro-fertilisation (IVF-ET) and an active tuberculosis can have massive and life-threatening consequences. We are showing in our case-report the symptoms, diagnostic investigations and the therapy of a patient with exacerbated tuberculosis after an IVF-pregnancy. As a conclusion preventive measures should be taken; varios options will be discussed.
    Notes: Zusammenfassung Das gemeinsame Auftreten einer Schwangerschaft nach In-Vitro-Fertilisation (IVF-ET) und einer aktiven Tuberkuloseerkrankung kann weitreichende, lebensbedrohliche Folgen haben. Wir stellen in unserer Kasuistik die Symptomatik, Diagnostik und Therapie einer Patientin mit exazerbierter Tuberkulose nach IVF-Gravidität dar. Die Konsequenz sollten Vorsorgemaßnahmen sein; verschiedene Möglichkeiten werden diskutiert.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract HBsAg was determined quantitatively by radioimmunoassay and by Laurell electrophoresis in sera of 90 patients with acute hepatitis B, 57 patients with chronic hepatitis B, and 154 HBsAg positive blood donors. Of 55 patients with clearance of HBsAg from the circulation within six months, 54 (98 %) showed an at least 50 % reduction in concentration within 16 days. All 55 patients had such a decrease within 20 days. No such decrease was found in seven patients with acute hepatitis B who became HBsAg carriers. Therefore, quantitative HBsAg concentration in paired sera seems to be a reliable and early prognostic marker in acute hepatitis B. In patients with clearance of HBsAg most of the antigen is already present in the circulation at hospitalization and is eliminated with a mean half-life of 8.8 days. Patients with chronic hepatitis exhibit on average nearly the same HBsAg concentration (about 40,000 ng/ml) as patients with acute hepatitis B at hospitalization (about 39,000 ng/ml) and HBsAg positive blood donors on average a lower HBsAg concentration (about 8,000 ng/ml).
    Type of Medium: Electronic Resource
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