Note: Cover -- Title -- Copyright -- Dedication -- Contents -- Foreword -- Preface -- Acknowledgments -- List of abbreviations and acronyms -- 1 Introduction: setting the scene -- 2 The Anthropocene and planetary boundaries: conditioners of sustainable development -- 3 Foresight and innovation: searching for the right future -- 4 Education: towards universal understanding -- 5 Science: the complexity of searching the truth -- 6 Industry, engineering, further complexity: steam engines and more -- 7 Philosophia moralis: systems stretched to the breaking point -- 8 Water: simple matter of special complexity -- 9 Biological diversity: bountiful Mother Nature -- 10 Global climate change: humanity's supreme challenge -- 11 Diplomacy and foreign trade: weaving the web of international intercourse -- 12 The military: risk management-plus, not perversity -- 13 Migration: when exit becomes exodus -- 14 Sustainable development: Homo sapiens' Holy Grail -- 15 Risks, new departures, global solutions: challenges of a complex frontier -- Further reading -- Index.

Note: Cover -- Title Page -- Copyright -- Contents -- Foreword by Edward O.Wilson -- I. Origin and Spread, Present and Future Range -- Prelude: And What Do You Do for a Living? -- Chapter 1. A Quick Tour of Fire Ant Biology -- Chapter 2. The Species of Fire Ants and Their Biogeography -- Chapter 3. An Atlas of Fire Ant Anatomy -- Chapter 4. Getting There -- Interlude: Beachhead Mobile -- Chapter 5. La Conquista: Spreading Out -- Interlude: Another Immigrant Moves West -- Chapter 6. Predicting Future Range Limits -- II. Basic Needs and the Monogyne Colony Cycle -- An Important Note: Monogyne and Polygyne Social Forms -- Chapter 7. Shelter -- Interlude: There's Nothing Like Getting Plastered -- Chapter 8. Space -- Chapter 9. Food -- Interlude: Mundane Methods -- Chapter 10. Mating and Colony Founding -- Interlude: Spring among the Fire Ants -- Chapter 11. The Claustral Period -- Interlude: Sharon's House of Beauty -- Chapter 12. The Incipient Phase and Brood Raiding -- Chapter 13. Dependent Colony Founding -- Chapter 14. Colony Growth -- Chapter 15. Relative Growth and Sociogenesis -- Interlude: The Porter Wedge Micrometer -- Chapter 16. Colony Reproduction and the Seasonal Cycle -- III. Family Life -- Interlude: Deby Discovers Ants -- Chapter 17. Nestmate and Brood Recognition -- Interlude: Ant ID Systems -- Chapter 18. Division of Labor -- Interlude: Moving Up in a Harvester Ant Colony -- Chapter 19. Adaptive Demography -- Interlude: Driving to Work with Odontomachus -- Chapter 20. The Organization of Foraging -- Interlude: Who's in Charge Here? -- Chapter 21. Food Sharing within the Colony -- Interlude: The Fire Ant on Trial -- Chapter 22. Venom and Its Uses -- Interlude: You Call That Pain!? -- Chapter 23. Social Control of the Queen's Egg-laying Rate -- Interlude: Catching Queens -- Chapter 24. Necrophoric Behavior -- IV. Polygyny. , Chapter 25. Discovery of Polygyny -- Interlude: I Want This to Be Accurate -- Chapter 26. The Suppression of Independent Colony Founding in Polygyne Colonies -- Chapter 27. The Nature and Fate of Polygyne Alates -- Interlude: A Useful Tool -- Chapter 28. Polygyne Mating, Adoption, Execution -- Chapter 29. Biological Consequences of Polygyny -- V. Populations and Ecology -- Chapter 30. Hybridization between Solenopsis invicta and S. richteri -- Chapter 31. Populations of Monogyne Fire Ants -- Interlude: Gang Wars -- Chapter 32. Territorial Behavior and Monogyne Population Regulation -- Chapter 33. Ecological Niche -- Chapter 34. Solenopsis invicta and Ant Community Ecology -- Interlude: Membership in a Prestigious Organization -- Chapter 35. Solenopsis invicta and Other Communities -- Chapter 36. Fire Ants and Vertebrates -- Interlude: A Microsafari in Antland -- Chapter 37. Biological Control -- Interlude: The Heartbreak of Parasitoids -- Some Final Words -- References -- Acknowledgments -- Index -- Color plates follow page.

Note: Intro -- In Memorium -- Preface -- Acknowledgements -- Contents -- Chapter 1: Introduction -- Warning: A Theoretical Definition -- Why Are Some Hazard Warnings Heeded and Others Not Heeded? -- The Value and Limits of Traditional Warnings -- Traditional vs. Interdisciplinary Warnings -- A Note on Human Factors and Ergonomics -- Organization and Scope of the Volume -- Bibliography -- Chapter 2: Historical, Technical, and Social Evolution of U.S. Warning Systems -- The Early History of Severe Weather Warnings -- Meteorology of the Classical and Renaissance Eras -- 1870-1948: Early Science, Institutional Support, and Stalled Progress -- Creation of the Weather Bureau -- 1948: Lifting the Ban on Tornado Warnings -- Modern Warning Systems: Evolution of Core Technologies and Practices -- Detection and Prediction of Severe Weather -- Sensor Networks -- Development of Remote Sensing and Radar Technologies -- Forecast Technologies: Numerical Weather Prediction -- Spotter Networks -- Warning Communication -- Storm-Based Warnings and Impact-Based Warnings (IBWs) -- Sirens -- Radio and Television -- NOAA Weather Radio -- A Decline in Tornadic Mortality and the Need for an Increased Focus on Social Science -- Conclusion -- Bibliography -- Chapter 3: Public Warnings Response -- Warning Response Model -- Warning Response in the Social System -- Model Stages: A Review of Literature -- Reception -- Informal Social Networks -- Language Barriers to Reception -- Demographic Determinants of Reception -- Siren Limitations -- Understanding -- Past Disaster Experience -- Warning Language, Format, and Content -- Visualization Formats -- Belief -- Trust in Authorities and Experts -- Environmental Cues -- Message Frequency -- Method or Channel of Communication -- False Alarms and Warning Skepticism: An Ongoing Debate -- Demographic Characteristics -- Threat Confirmation. , Personalization of Risk -- Cultural Myths -- Cultural Fatalism -- Social and Environmental Cues -- Warning Content, Past Experience, and Demographics -- Believe Protection Action Necessary -- Believe Protective Action is Feasible -- Protective Action: Resources and Lead Time -- On the Availability and Use of Resources to Assist in Protective Action -- Conjectures and Propositions Regarding the Role of Leadtime in Protective Action -- Official vs. Community vs. Individual Lead Times -- An Unanswered Question: What Is the Ideal Lead Time? -- The Question of Model Dynamics -- Hypotheses About Stage Transition -- Dependence -- Directionality -- Demographic Variables Are Not Consistent Across Stages -- Conclusion -- Bibliography -- Chapter 4: Institutional Warning Response: Emergency and Scientific Institutions -- Obstacles to Successful Warning at the Institutional Level -- Weather Forecasters -- What Affects Warning Judgements in General? -- Emergency Managers -- To Warn or Not to Warn: Decision-Making Patterns Among Emergency Managers -- Media -- What Governs the Warning Process at the Institutional Level? -- Psychological -- Social Factors -- Cultural Obstacles -- Conclusion -- Bibliography -- Chapter 5: Towards a Model to Coordinate Interdisciplinary Weather Research -- Distinctions Between the Natural and Social Sciences as a Starting Point -- A Note on Definition and Terminology -- The Social Scientist in Interdisciplinary Research -- A General Organizational Model for Interdiciplinary Research -- Common Roles -- Towards an Organizational Structure of the Interdisciplinary Project -- Establishing and Maintaining an Interdisciplinary Culture -- End-User Engagement -- Conclusion -- Bibliography -- Chapter 6: Building and Troubleshooting an Interdisciplinary Project. , Establishing a Global Question and Transforming Applied Scientific Questions into Social Science Hypotheses -- Complexity and Loss of Focus on the ``Global Question´´ -- Trust and Legitimacy Building Across Disciplines -- Engagement of Stakeholders -- Conflict Management -- Rewards and Incentive Structures Across the Disciplines -- Assessment of Success -- A Blueprint for the Design of an Interdisciplinary Project -- Define the Problem Globally -- Identify Key Stakeholders Early and Incorporate Them into the Design Process -- Develop a Budget Capable of Addressing the Global Question: Not Merely Technical Innovation -- Establish an Ongoing Culture of Interdisciplinarity -- Plan to Manage Conflict and Morale Issues -- Conclusion -- Bibliography -- Chapter 7: A Case Study in Interdisciplinarity: CASA (Collaborative Adaptive Sensing of the Atmosphere) -- ERC-CASA: A Brief Overview -- Organization of CASA -- Emergency Manager Surveys -- Studies of Oklahoman Emergency Managers -- End-User Simulations -- Policy Development -- Public Response Research -- Overview of CASA´s Public Response Fieldwork -- New Orleans: Disaster in the Context of Recovery -- Missouri -- Tennessee -- Synopsis of Results -- Reception -- Understanding -- Belief -- Confirmation -- Personalization -- Determining Whether Protective Action is Necessary and Feasible -- Protective Action -- Conclusion: Integration and Connection to System Design -- Bibliography -- Chapter 8: Emerging Interdisciplinary Themes: Social Media -- How Does Social Media ``Fit´´ into Our Current Understanding of Warnings? -- Conceptualization of Social Media as a Warning Tool -- How Has Social Media Altered Traditional Disaster Processes? -- Rumor -- Crowdsourcing -- The Psychological and Social Psychological Impacts of Social Media Warnings -- Population and Culture -- Conclusion -- Bibliography. , Chapter 9: Conclusion -- Where Do We Go from Here? Policy Towards Addressing Unanswered Questions and Future Directions -- A Final Note on Complexity, Risk, and Interdisciplinary Research -- Bibliography.

Note: Front Cover -- The Togaviruses: Biology, Structure, Replication -- Copyright Page -- Table of Contents -- List of Contributors -- Preface -- Chapter 1. Introduction -- I. Historical Background: The Arthropod-Borne Viruses (Arboviruses) -- II. The Togaviridae -- III. Prospectus -- References -- Chapter 2. Antigenic Characteristics and Classification of Togaviridae -- I. Introduction -- II. Antigenic Relationships among the Togaviridae -- III. Methods Used to Study Interrelationships -- IV. Other Factors Affecting Cross-Protection -- V. Medical and Biological Significance of Interfamily Relationships -- VI. Evolutionary Aspects of Togaviridae -- References -- Chapter 3. Medical Significance of Togaviruses: An Overview of Diseases Caused by Togaviruses in Man and in Domestic and Wild Vertebrate Animals -- I. Introduction -- II. Description of Major Disease Groups -- III. Laboratory Infections -- IV. An Overview -- References -- Chapter 4. Virus-Host Interactions in Natural and Experimental Infections with Alphaviruses and Flaviviruses -- I. Complexities of "Virulence -- II. Target Organs in Alpha- and Flavivirus Infections -- III. Phylogenetic Host Determinants of Virulence-Vertebrate versus Arthropod Host Systems -- IV. Viral Virulence Markers: The Question of Genotypic versus Phenotypic Polymorphism -- V. Conclusions -- References -- Chapter 5. Immunological Parameters of Togavirus Disease Syndromes -- I. Introduction -- II. Immunological Aspects of Dengue Infection -- III. The Immune Enhancement Hypothesis -- IV. Comment -- V. Appendix -- References -- Chapter 6. Epidemiology of Arthropod-Borne Togaviruses: The Role of Arthropods as Hosts and Vectors and of Vertebrate Hosts in Natural Transmission Cycles -- I. Introduction -- II. The Alphaviruses -- III. The Flaviviruses -- References. , Chapter 7. Arthropods as Hosts and Vectors of Alphaviruses and Flaviviruses-Experimental Infections -- I. Introduction -- II. Considerations in Undertaking Experimental Infection of Arthropods -- References -- Chapter 8. Togavirus Morphology and Morphogenesis -- I. Introduction -- II. The Alphavirus Genus -- III. The Flavivirus Genus -- IV. The Rubivirus Genus -- V. The Pestivirus Genus -- VI. Unclassified Togaviruses -- VII. Comparisons and Conclusions -- References -- Chapter 9. Alphavirus Proteins -- I. Protein Composition of Alphaviruses -- II. Isolation of Alphavirus Proteins -- III. Topography of the Spike Proteins in the Membrane -- IV. Functions of the Alphavirus Spike Glycoproteins -- References -- Chapter 10. Lipids of Alphaviruses -- I. Introduction -- II. Structure of Lipids -- III. Origin and Diversity of Lipids -- IV. Role of Lipids -- References -- Chapter 11. The Genome of Alphaviruses -- I. Physical Properties of the Alphavirus Genome -- II. Genetic Content and Organization of the Alphavirus Genome -- References -- Chapter 12. Synthesis of Alphavirus RNA -- I. Introduction -- II. Early Events -- III. Nature and Synthesis of Alphavirus Minus-Strand RNA -- IV. Nature and Synthesis of Alphavirus Plus-Strand RNA -- V. Mechanism of Synthesis of 26 S RNA -- VI. Regulation of the Synthesis of 42 and 26 S Plus-Strand RNA -- VII. Kinetics of Alphavirus Plus- and Minus-Strand Synthesis and of Polymerase Formation -- VIII. Mechanistic Aspects of the Synthesis of Alphavirus RNA -- References -- Chapter 13. Translation and Processing of Alphavirus Proteins -- I. Introduction -- II. Translation of Viral Proteins -- III. Glycosylation of Viral Envelope Proteins -- IV. Fatty Acid Acylation of Envelope Proteins -- V. Stoichiometry of Viral Structural Gene Products -- VI. Conclusion -- References. , Chapter 14. Mutants of Alphaviruses: Genetics and Physiology -- I. Introduction -- II. Types of Mutants -- III. Genetic Interactions between Alphaviruses -- IV. Functional Defects of the Alphavirus ts Mutants -- V. Concluding Remarks -- References -- Chapter 15. Defective Interfering Alphaviruses -- I. Introduction -- II. First Reports of Defective Interfering Particles of Alphaviruses -- III. Properties of Alphavirus Defective Interfering Particles -- IV. Intracellular Viral Defective Interfering RNAs -- V. Sequences Found in Defective Interfering RNAs -- VI. Role and Influence of the Host Cell in the Generation and Replication of Alphavirus Defective Interfering Particles -- VII. Defective Interfering Particles in Persistently Infected Cultures -- VIII. Defective Interfering Particles in the Whole Animal -- IX. Concluding Remarks -- References -- Chapter 16. Effects of Alphaviruses on Host Cell Macromolecular Synthesis -- I. Introduction -- II. The Effects of Lytic Infection of Vertebrate Cell Cultures on the Macromolecular Synthesis of the Host Cell -- III. Effects of Noncytolytic Infection of Arthropod Cell Cultures on Macromolecular Synthesis of Host Cell -- References -- Chapter 17. The Assembly of Alphaviruses -- I. Introduction -- II. Assembly of Alphavirus Nucleocapsids -- III. Assembly of Alphavirus Membranes -- IV. Envelopment of the Alphavirus Nucleocapsid -- V. Future Research in Alphavirus Assembly -- References -- Chapter 18. Chemical and Antigenic Structure of Flaviviruses -- I. Introduction -- II. Physical and Chemical Characteristics -- III. Virion RNA -- IV. Proteins and Glycoproteins -- V. Lipids -- VI. Antigenic Characteristics -- VII. Present and Future Investigations -- References -- Chapter 19. Replication of Flaviviruses -- I. Introduction -- II. Transcription -- III. Virus-Specified Proteins. , IV. Protein Synthesis in Infected Cells -- V. Assembly and Maturation -- VI. Summary of Flavivirus Replication -- References -- Chapter 20. Togaviruses in Cultured Arthropod Cells -- I. Introduction -- II. Arthropod Cell Lines Used for the Growth of Togaviruses -- III. Growth of Viruses in Cell Lines of Arthropod Origin -- IV. Comparative Aspects of Togavirus Replication in Mosquito and Vertebrate Cells -- V. Cytopathic Effect in Mosquito Cells Infected with Togaviruses -- VI. Mosquito Cells Persistently Infected with Togaviruses -- VII. Mosquito Cells and Defective Interfering Particles of Alphaviruses -- VIII. Sindbis Virus Mutants in Cultured Mosquito Cells -- IX. Contaminating Viruses in Cultured Mosquito Cells -- X. Mutants of Mosquito Cells and Their Use for the Study of Togaviruses -- XI. Concluding Remarks -- References -- Chapter 21. Non-Arbo Togaviruses -- I. Introduction -- II. Pestiviruses -- III. Rubivirus -- IV. Other Viruses -- V. Non-Arbo Flaviviruses -- VI. Discussion -- References -- Index.

Note: Cover -- Title Page -- Copyright Page -- TABLE OF CONTENTS -- SECTION 1: GENERAL CONCEPTS -- Chapter 1: The Classical Concepts of the Origin and Development of Malignant Tumors -- Chapter 2: Control of Gene Expression during Cell Cycle and Growth of Mammalian Cells -- Chapter 3: Transit, Exit, and Arrest Models for Control of the Mammalian Cell Cycle -- Chapter 4: Cancer-A Disease of Tissue Neogenesis? -- Chapter 5: Neoplasia and the Wound Response: The Lesson Learned from the Multistage Approach of Skin Carcinogenesis -- SECTION 2: CELL TRANSFORMATION -- Chapter 1: The Role of Polypeptide Growth Factors in Phenotypic Transformation of Normal Cells -- Chapter 2: Density-Development Control of Cell Proliferation: Molecular Mechanisms Involved in Contact-Inhibition -- Chapter 3: Cancer as a Mutation-Driven Evolutionary Process -- Chapter 4: Mutation-Driven Evolution of Rev-T -- Chapter 5: Expression of ras, myc, and erb-A Proto-Oncogenes in Preneoplastic Rat Liver during Chemical Carcinogenesis -- Chapter 6: Oncogene Expression in Preneoplastic and Neoplastic Lesions -- Chapter 7: Timing of Proto-Oncogene Replication and its Relationship to Transformation Sensitivity to Chemical Carcinogens -- Chapter 8: The Roles of Cell Proliferation and Gene Replication in Neoplastic Transformation -- Chapter 9: Oncogene Amplification: myc and neu Oncoproteins -- Chapter 10: Structure, Expression, and Oncogenic Activity of the myc Gene Family -- Chapter 11: The myc Family of Nuclear Oncoproteins: Structure, Biochemistry, and Activities -- SECTION 3: FROM FACTOR DEPENDENCE TO FACTOR INDEPENDENCE -- Chapter 1: Critical Variables for the Oncogene-Induced Immortalization of Fischer Rat Embryo Cells -- Chapter 2: Biological Aspects of the Process -- Chapter 3: Immortalization of Cultured Mammalian Cells: A brief Review of the Recent Literature. , Chapter 4: Transfer of an Extrachromosomal, Cytoplasmic Mouse DNA Leads to Immortalization of Human Lymphocytes without Induction of the Tumorigenic Phenotype -- Chapter 5: Growth Regulation in Normal and Malignant Melanocytes -- Chapter 6: Paracrine Interactions Govern the Progression of Lympho-hemopoietic Malignancies: Evidence from Long-Term Marrow Cultures -- Chapter 7: ras Oncogene Mediates Paracrine Interactions between Leukemic Progenitor Cells and Stromal Elements -- Chapter 8: Role of Oncogenes in the Abrogation of Growth Factor Requirements of Hemopoietic Cells -- Index.

Note: Intro -- Half Title -- Title Page -- Copyright Page -- Contents -- List of figures -- List of tables -- Preface -- Theme of this book -- Possible approaches to writing this book -- Depth of material -- Book structure -- Required background -- Caveats -- Before we start -- Acknowledgements -- Part I Background -- 1 Introduction -- 1.1 Answering the Key Business Question -- 1.1.1 Uniform pricing strategy -- 1.1.2 Price discrimination strategy -- 1.1.3 Strategy parts -- 1.2 Price effect -- 1.3 Pricing research approaches -- 1.4 Qualitative pricing research -- 1.4.1 Pharmaceuticals case study -- 1.4.2 Cost-plus pricing -- 1.4.3 Importance of qualitative information -- 1.5 Quantitative pricing research -- 1.5.1 The role of theory -- 1.5.2 The role of data and data analysis -- Revealed preference data -- Stated preference data -- 1.5.3 The role of statistical models -- Mechanistic model -- Statistical model -- 1.6 Simulators -- 1.7 Price elasticities -- 1.8 Summary -- Notes -- 2 Elasticities - Background and concept -- 2.1 Economic concept -- 2.2 Consumer surplus -- 2.3 The market demand curve -- 2.4 Elasticity concept -- 2.5 Properties of elasticities -- 2.6 Parallel shifts in demand -- 2.7 Cross-price elasticities -- 2.7.1 Elasticity constraints -- 2.7.2 Expenditures -- 2.8 Income elasticities -- 2.9 Elasticities and time -- 2.10 Some general demand function specifications -- 2.10.1 Isoelastic demand function -- 2.10.2 Log-linear demand function -- 2.11 Qualitative statements about elasticities -- 2.12 Summary -- Notes -- 3 Elasticities - Their use in pricing -- 3.1 The basics -- 3.2 Profit maximization -- 3.2.1 Monopoly firm profit maximization -- Myopic monopolist price -- 3.2.2 Perfectly competitive firm profit maximization -- 3.3 Pricing and market power -- 3.4 Pricing by the dominant firm -- 3.5 Pricing structures and elasticities. , 3.5.1 Definition of price discrimination -- 3.5.2 Price discrimination family -- First-degree price discrimination -- Second-degree price discrimination -- Third-degree price discrimination -- 3.5.3 Conditions for price discrimination -- 3.5.4 Price discrimination and Big Data -- 3.6 Summary -- Notes -- Part II Stated preference models -- 4 Conjoint analysis -- 4.1 Pricing Scenario -- 4.1.1 The pricing problem -- 4.1.2 Terminology -- 4.2 Basic conjoint model -- 4.3 What the consumer sees -- 4.4 Specifying the Price attribute -- 4.5 Design matrix background -- 4.5.1 Orthogonal design -- 4.5.2 Hadamard design -- 4.5.3 Foldover designs -- 4.5.4 Balanced incomplete block designs -- 4.5.5 Full factorial design -- 4.5.6 Fractional factorial design -- 4.5.7 Why use a design? -- One-factor-at-a-time experiments -- 4.5.8 Generating a design -- 4.5.9 Creating the design -- 4.6 Estimation -- 4.6.1 Digression: Coding -- Dummy coding -- Technical details of dummy coding -- Effects coding -- Technical details on effects coding -- Creating an effects coded design -- 4.6.2 OLS estimation for the Pricing Scenario -- 4.6.3 Logit estimation for the Pricing Scenario -- 4.7 Utility calculations -- 4.8 Analysis -- 4.8.1 Part-worth summary plots -- 4.8.2 Attribute importances -- 4.8.3 Elasticities -- Discrete price case -- Continuous price case -- 4.9 Other conjoint approaches -- 4.10 Software -- 4.11 Summary -- Notes -- 5 Discrete choice models -- 5.1 Pricing Scenario -- 5.1.1 The pricing problem -- 5.2 Types of choice models -- 5.3 The choice model - Utility maximization -- 5.3.1 Consumer homogeneity -- 5.3.2 Utility specification -- 5.3.3 Utility maximization -- 5.4 Choice probabilities -- 5.4.1 Digression: The EVI distribution -- 5.4.2 The conditional logit choice probability -- 5.4.3 Choice probability properties -- Equivalent differences property. , The Independence of Irrelevant Alternatives property -- 5.4.4 The none option -- 5.5 Estimation - Introduction -- 5.6 Treatment design: A Bayesian perspective -- 5.7 Estimation - Continued -- 5.8 Analysis -- 5.8.1 Attribute importances -- 5.8.2 Demand and choice elasticities -- 5.8.3 Elasticity analysis -- Continuous price variable -- Discrete price variable -- Aggregation -- 5.8.4 Willingness-to-pay analysis -- 5.8.5 Profilers and simulators -- 5.9 Software -- 5.10 Summary -- Notes -- 6 MaxDiff models -- 6.1 A Pricing Scenario: Casino pricing strategies -- 6.1.1 The Pricing Scenario -- 6.1.2 The MaxDiff procedure -- 6.1.3 MaxDiff vs. discrete choice -- 6.2 Design matrix development -- 6.2.1 Conventional BIBD notation -- 6.2.2 Generating a BIBD -- 6.2.3 Pricing Scenario BIBD -- 6.2.4 An alternative design approach: Split-plots -- 6.2.5 Pricing Scenario final design -- 6.3 Estimation -- 6.3.1 Data arrangement -- 6.3.2 Aggregate-level estimation -- 6.3.3 Disaggregate-level estimation -- Digression: HB -- 6.4 Analysis -- 6.4.1 Counting analysis -- 6.4.2 Aggregate-level analysis -- Pricing Scenario: Aggregate estimation -- 6.4.3 Disaggregate-level analysis -- Pricing Scenario: Disaggregate estimation -- A brief introduction to TURF analysis following MaxDiff -- Pricing Scenario: TURF analysis -- 6.5 Pricing product add-on options -- 6.5.1 Pricing Scenario: Wedding caterer options -- 6.5.2 Treatment design -- 6.5.3 Estimation -- 6.6 Software -- 6.7 Summary -- Notes -- 7 Other stated preference methods -- 7.1 van Westendorp Price Sensitivity Meter -- 7.1.1 Pricing Scenario -- 7.1.2 The four questions -- 7.1.3 Analysis -- 7.1.4 The Pricing Scenario - Analysis -- 7.2 Gabor-Granger -- 7.2.1 Methodology -- 7.2.2 Analysis -- 7.2.3 Pricing Scenario -- 7.2.4 Problems with the methodology -- 7.3 A/B price testing -- 7.3.1 Pricing scenario -- 7.3.2 Methodology. , Digression on odds calculation -- 7.4 Software -- 7.5 Summary -- Notes -- Part III Price segmentation -- 8 Price segmentation: Basic models -- 8.1 What is price segmentation? -- 8.2 Why price segment the market? -- 8.3 Segmentation and heterogeneity -- 8.4 Developing pricing segments -- 8.4.1 Modeling engine: A priori methods -- 8.4.2 Modeling engine: Post hoc methods -- 8.5 Pricing Scenario -- 8.5.1 The business problem -- 8.5.2 Likely elasticities -- 8.5.3 Company data -- 8.5.4 Simulated data -- 8.5.5 Digression: Multilevel effects -- 8.6 A priori modeling -- 8.6.1 Model specification -- 8.6.2 Model estimation -- 8.7 Post hoc modeling -- 8.7.1 Unsupervised learning methods -- Pricing Scenario: Hierarchical clustering -- Pricing Scenario: K-means clustering -- Digression on coding and elasticities -- 8.7.2 Supervised learning -- Decision trees -- Pricing Scenario: Decision tree -- Ensembles of trees -- 8.8 Software -- 8.9 Summary -- Notes -- 9 Price segmentation: Advanced models -- 9.1 Latent variable modeling -- 9.1.1 Types of latent variable models -- 9.1.2 What is latent variable modeling? -- 9.1.3 Latent regression analysis -- Model components -- Digression on notation -- Latent regression model -- Estimation - The expectation maximization algorithm -- Selecting the number of segments -- Pricing Scenario: Latent regression model -- 9.1.4 Choice latent class models -- Conjoint latent class models -- Discrete choice latent class models -- 9.2 Gaussian mixture modeling -- 9.3 Multilevel models -- 9.4 Software -- 9.5 Summary -- Notes -- Part IV Big Data and econometric models -- 10 Working with Big Data -- 10.1 A motivation for using Big Data -- 10.2 Big Data: Definition and issues -- Volume -- Velocity -- Variety -- Veracity -- 10.2.1 Aspects of Big Data -- 10.2.2 Pricing Scenario -- 10.2.3 Data warehouses and data marts. , 10.3 Big Data and pricing -- 10.3.1 NT≫Q: Significance testing issue -- 10.3.2 Q≫NT: Multiple comparisons issue -- 10.4 A role for sampling -- 10.5 Data visualization -- 10.5.1 Displaying leakages -- 10.5.2 Trends -- 10.5.3 Patterns -- 10.5.4 Anomalies -- 10.6 Software -- 10.7 Summary -- Notes -- 11 Big Data pricing models -- 11.1 Pricing Scenario -- 11.2 Modeling phases -- 11.2.1 Data Block -- Management input -- Data collection -- Data engine -- 11.2.2 Modeling Block -- Varying-intercept, constant-slope models -- Constant-intercept, varying-slope Models -- Varying-intercept, varying-slope Models -- 11.2.3 Analysis Block -- 11.3 Probability of a win model -- 11.4 Software -- 11.5 Summary -- Notes -- 12 Big Data and nonlinear prices -- 12.1 Linear and nonlinear pricing -- 12.1.1 A simple demand model -- 12.2 Forms of nonlinear pricing -- 12.2.1 Quantity discounts -- Devising a discount schedule -- Elasticity measurement -- Further complications -- 12.2.2 Bundling -- 12.2.3 Product line pricing -- 12.3 Software -- 12.4 Summary -- Notes -- Bibliography -- Index.

Note: Cover -- Title Page -- Copyright Page -- Preface -- The Editor -- Contributors -- Table of Contents -- Section 4: Growth Regulation -- Chapter 1: The Cyclin (PCNA) Probe of the Cell Cycle -- Chapter 2: Cyclin (PCNA): A Ubiquitous Cell Cycle Regulated Protein with a Role in DNA Replication -- Chapter 3: Signals for Nuclear Localization in PDGF-Related Proteins -- Chapter 4: The Role of Growth Factors in Normal and Leukemic Myeloid Blood Cell Production -- Chapter 5: Clinical Utility of Hematopoietic Growth Factors -- Chapter 6: Lymphocyte Surface Molecules Alter Hematopoietic Progenitor Cell Growth -- Chapter 7: Role of Cell Surface-Associated Molecules in Normal and Malignant Cell Proliferation -- Chapter 8: Protooncogene Expression in Normal, Preleukemic, and Leukemic Cells and its Relationship to Differentiation and Proliferation -- Chapter 9: Stimulation of Anchorage-Independent Growth of Human Tumor Cells by Macrophages -- Chapter 10: Regulation of Cancer Cell Growth by Inflammatory Products -- Chapter 11: Function of Gangliosides in Cellular Proliferation -- Chapter 12: Novel Regulation of Cell Growth by Endogenous Gangliosides -- Chapter 13: The Epidermal Growth Factor Receptor-Transforming Growth Factor Alpha Autocrine Cycle -- Chapter 14: Autocrine Regulation in Human Pancreatic Cancer -- Chapter 15: Molecular Basis for Plasminogen Activation, Surface Proteolysis, and their Relation to Cancer -- Chapter 16: Specificity and Properties of the Human Urokinase Receptor -- Chapter 17: Multiple-Step Regulation of S6 Phosphorylation by a Protein Kinase and Phosphatase -- Chapter 18: Beyond the S6 Kinase and S6 Phosphatase -- Chapter 19: Glandular Kallikreins as Growth Factor Processing Enzymes -- Chapter 20: Modulation of Growth Factor Action by TPA and non-TPA-Type Tumor Promoters. , Chapter 21: Growth Factors and Signal Transduction Involving Inositol Lipids -- Section 5: Differentiation, Tissue Interactions -- Chapter 1: Morphogenesis of the Mesoderm in Early Avian Development: Sequential Phenotypic Transformations -- Chapter 2: Positional Instability in Early Development and Cancer -- Chapter 3: Anticancer Activity: A Review of Experimental and Clinical Studies -- Chapter 4: Anticancer Activity Induced by Cellular Differentiation -- Chapter 5: Contributions with Regard to Stromal Alterations in Carcinogenesis -- Chapter 6: Current Views on the Active Involvement of Connective Tissue in Carcinogenesis -- Chapter 7: Tissue Sizing: A Community Control of Neoplastic Growth -- Chapter 8: A Microenvironmental Model of Mammalian Cell Cycle Variability -- Chapter 9: Cell Death by Apoptosis: Significance for Regulation of Homeostasis of Cell Number and its Disturbance during Cancer Development -- Index.