GLORIA

GEOMAR Library Ocean Research Information Access

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Document type
Language
  • 1
    Online Resource
    Online Resource
    Basel :S. Karger AG,
    Keywords: Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (203 pages)
    Edition: 1st ed.
    ISBN: 9783318011746
    Series Statement: Chemical Immunology and Allergy Series ; v.86
    Language: English
    Note: Cover -- Contents -- Preface -- Antimicrobial Peptides: Basic Features and Clinical Relevance -- Antimicrobial Peptides in Drosophila: Structures, Activities and Gene Regulation -- Abstract -- Introduction -- Drosophila Defensin, An Anti-Gram-Positive Peptide -- The Antifungal Drosomycin -- Antifungal Peptide -- Metchnikowin, A Cysteine-Free Drosophila Antifungal Peptide -- Cecropins, alpha-Helical Peptides Largely Distributed in Higher Insect Orders -- Drosocin, An Anti-Gram-Negative O-Glycopeptide -- Diptericin, An Anti-Gram-Negative O-Glycopeptide -- Attacins, Large Polypeptides with Antibacterial Properties -- MPAC, the Drosophila Attacin C Pro-Domain with Antibacterial Properties -- Rel Proteins Control Expression of Antimicrobial Peptide Genes -- The Toll and IMD Pathways Control Inducible Expression of AMP Genes -- Other Signaling Pathways Activated during the Drosophila Immune Response -- Hemocytes in the Drosophila Immune Response -- Epithelial Responses in Drosophila -- Concluding Remarks -- Acknowledgements -- References -- Antimicrobial Peptides in Human Skin -- Abstract -- Introduction -- beta-Defensins -- Human beta-Defensin-2 -- Human beta-Defensin-3 -- Human beta-Defensin-1 -- Human beta-Defensin-4 -- Cathelicidin LL-37 -- Serine Protease Inhibitors Antileukoprotease and Elafin -- Dermcidin -- Adrenomedullin -- Neutrophil Gelatinase-Associated Lipocalin -- RNase 7 -- Skin Disease Implications -- Conclusion -- References -- Human Defensins in Crohn's Disease -- Abstract -- Introduction -- Epidemiology: The Role of Hygiene -- Pathophysiology: The Role of Luminal and Mucosal Bacteria -- Defensin Expression and Regulation in the Healthy Intestinal Tract -- Defensins and Inflammatory Bowel Diseases -- NOD2, A Peptidoglycan Receptor and Defensin Expression -- Toll-Like Receptors and Their Expression in Inflammatory Bowel Diseases. , Therapy: The Role of Antibiotics and Probiotics -- Concluding Remarks -- Acknowledgements -- References -- Antimicrobial Peptides in Lung Inflammation -- Abstract -- Introduction -- AMPs Are Expressed in the Respiratory Tract -- Host Defense in the Airways -- AMPs in the Human Lung -- Regulation of the AMPs in the Lung -- Functions of AMPs in the Respiratory Tract -- Antimicrobial Activity -- Inflammation, Angiogenesis, and Cell Function -- Role of AMPs in Pulmonary Disease -- Pneumonia and Tuberculosis -- Cystic Fibrosis and Diffuse Panbronchiolitis -- Asthma and Chronic Obstructive Pulmonary Disease -- Adult Respiratory Distress Syndrome -- Pulmonary Fibrosis and Sarcoidosis -- Conclusions -- Acknowledgement -- References -- Reciprocal Interactions of Host Cells and Microbes -- Bacterial Evasion of Innate Defense at Epithelial Linings -- Abstract -- How to Circumvent Physical Removal from Body Surfaces -- Overcome Space and Nutrient Deprivation -- Resisting the Low-pH Defense Barrier -- Avoid Protease Mediated Destruction and Opsonization -- Evade Recognition and Cell Activation -- Withstand Targeted Destruction -- Active Penetration of the Epithelial Cell Barrier -- Acknowledgements -- References -- Recognition of Bacterial Products by Toll-Like Receptors -- Abstract -- Mammalian Toll-Like Receptors and Their Ligands -- Extracellular Recognition of TLR Ligands -- TLR4 -- TLR2, TLR2/TLR1, and TLR2/TLR6 -- TLR10 -- TLR5 -- TLR11 -- Intracellular Recognition of TLR Ligands -- TLR3 -- TLR7/TLR8 -- TLR9 -- Conclusion -- References -- TLR Signalling and the Function of Dendritic Cells -- Abstract -- Introduction -- What Are Toll-Like Receptors? -- Toll-Like Receptors Recognize Various Molecules -- Signalling Pathway of TLRs -- MyD88-Dependent Pathway -- MyD88-Independent Pathway -- TIRAP/Mal -- TRIF -- TRAM -- The Role of TLR Family in the Host Defence. , TLRs Stimulate DCs to Induce T Cell Activation -- LPS-Stimulated MyD88-Deficient DCs -- DC Subset-Dependent Cytokine Production -- Conclusion -- References -- Contribution of T Cells to Epithelial Defense -- Immunosurveillance by gama/deltaT Cells: Focus on the Murine System -- Abstract -- TCRgamadelta+ Intraepithelial Lymphocytes -- Immunoprotective Roles of gamadelta T Cells in the Tissues -- Immunoregulatory Roles of Local gamadelta T Cells -- gamadelta+ T Cells and Tumor Surveillance -- gamadelta+ T Cell Regulation of Epithelial Malignancy -- From gamadelta Cell Biology in Mice to Immunosurveillance in Humans -- Immunological Mechanisms Highlighted by gamadelta Cells - Towards the Clinic -- References -- gamadelta T Cells Link Innate and Adaptive Immune Responses -- Abstract -- Introduction -- Vgama9/Vdelta2 T Cells -- Vgama9/Vdelta2 T Cells Are Expanded by Various Microbes -- Vgama9/Vdelta2 T Cells Are Activated by Non-Peptide Antigens -- Non-Mevalonate Pathway Intermediates Are the Most Potent Vgama9/Vdelta2 Activators -- Alkylamines Activate Vgama9/Vdelta2 T Cells -- N-Bisphosphonates Stimulate Vgama9/Vdelta2 T Cells -- Vgama9/Vdelta2 T Cells Can Kill Bacteria within Hours after Activation -- The Vgama9/Vdelta2 TCR Repertoire Is Shaped by Non-Peptide Antigens -- Vgama9/Vdelta2 T Cells and Tumor Surveillance -- Activation of Vgama9/Vdelta2 T Cells as a Therapeutic Approach in Tumor Treatment: From Bench to Bedside -- Vdelta1 Cells -- Vdelta1 T Cells Are the Dominant gamma/delta T Cell Population at Mucosal Surfaces -- Vdelta1 T Cells Are Activated by MICA/B -- Vdelta1 T Cells Are Activated by Glycolipids Presented by CD1 -- Lipid Extracts from Gram-Negative Bacteria Indirectly Stimulate Vdelta1T Cells -- TCR Repertoire of Vdelta1 T Cells -- The Role of Vdelta1 T Cells in Microbial Infections -- The Role of Vdelta1 T Cells in Tumor Recognition. , Migration and Homing of gamma/delta T cells -- Chemokine Expression of Peripheral gamma/delta T cells -- gamma/delta T Cells Can Be Polarized into TH1/TH2 Cells -- Chemokine Expression of Mucosal gamma/delta T Cells -- gamma/delta T Cells Can Have Immunosuppressive and Anti-Inflammatory Activities -- Expression of Toll-Like Receptors -- Concluding Remarks -- References -- Author Index -- Subject Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- L -- M -- N -- P -- R -- S -- T -- Y.
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin / Heidelberg,
    Keywords: Diagenesis. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (462 pages)
    Edition: 1st ed.
    ISBN: 9783642828126
    DDC: 551.4/24
    Language: English
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    Keywords: Mathematics ; Mathematics, general ; Mathematics ; Konferenzschrift 1976 ; Differentialgleichung ; Numerische Integration ; Differentialgleichung ; Numerisches Verfahren ; Differentialgleichung ; Numerisches Verfahren ; Differentialgleichung ; Numerisches Verfahren ; Differenzengleichung ; Randwertproblem
    Description / Table of Contents: Some convergence results for the PEACEMAN-RACHFORD method in the noncommutative case -- Efficient embedded runge — Kutta methods -- Collocation and iterated defect correction -- Verallgemeinerte Runge-Kutta Verfahren zur Loesung steifer Differentialgleichungssysteme -- A fast iterative method for solving poisson’s equation in a general region -- On the stability regions of multistep multiderivative methods -- Prädiktoren mit vorgeschriebenem Stabilitätsverhalten -- Oscillation and nonoscillation theorems for a second order nonlinear functional differential equation -- Eine spezielle Integralgleichung erster Art -- Ein Zusammenhang zwischen Aufgaben monotoner Art und Intervall-Mathematik -- The RKFHB4 method for delay — Differential equations -- Spiegelung von Stabilitätsbereichen -- On fast poisson solvers and applications -- Considerations concerning a theory for ode-solvers -- Boundary value problems in infinite intervals -- Capacitance matrix methods for Helmholtz’s equation on general bounded regions.
    Type of Medium: Online Resource
    Pages: Online-Ressource (XII, 224 p, online resource)
    ISBN: 9783540359708 , 9783540085393
    Series Statement: Lecture Notes in Mathematics 631
    RVK:
    Language: English
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Online Resource
    Online Resource
    [Dortmund] : [Technische Universität, Fakultät für Mathematik]
    Keywords: Finite-Elemente-Methode ; Methode der kleinsten Quadrate ; Navier-Stokes-Gleichung
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (15 Seiten, 195,47 KB) , Diagramme
    Series Statement: [Ergebnisberichte angewandte Mathematik] [No. 478]
    DDC: 510
    RVK:
    Language: English
    Note: Reihentitel und -zählung der Druckausgabe entnommen , Unterschiede zwischen dem gedruckten Dokument und der elektronischen Ressource können nicht ausgeschlossen werden
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 5273-5285 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Methods of implementation of classical molecular dynamics simulations of moderate size molecule vibrational energy relaxation and analysis of their results are proposed. Two different approaches are considered. The first is concerned with modeling a real nonequilibrium cooling process for the excited molecule in a solvent initially at equilibrium. In addition to the solute total, kinetic, and potential energy evolution, that define the character of the process and the rate constant or relaxation time, a great deal of important information is provided by a normal mode specific analysis of the process. Expressions for the decay of the normal mode energies, the work done by particular modes, and the vibration–rotation interaction are presented. The second approach is based on a simulation of a solute–solvent system under equilibrium conditions. In the framework of linear nonequilibrium statistical thermodynamics and normal mode representation of the solute several expressions for the rate constant are derived. In initial form, they are represented by integrals of the time correlation functions of the capacities of the solute–solvent interaction atomic or normal mode forces and include the solute heat capacity. After some approximations, which are adequate for specific cases, these expressions are transformed to combinations of those for individual oscillators with force–force time correlation functions. As an attempt to consider a strongly nonequilibrium situation we consider a two-temperature model and discuss the reason why the rate constant can be independent on the solute energy or temperature. Expressions for investigation of the energy redistribution in the solvent are derived in two forms. One of them is given in the usual form of a heat transfer equation with the source term describing the energy flux from the excited solute. The other form describes the energy redistribution in the solvent in terms of capacity time correlation functions and can be more convenient if memory effects and spatial dispersion play an important role in energy redistribution in the solvent. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 5286-5299 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Results of nonequilibrium molecular dynamics simulations of vibrational energy relaxation of azulene in carbon dioxide and xenon at low and high pressure are presented and analyzed. Simulated relaxation times are in good agreement with experimental data for all systems considered. The contribution of vibration–rotation coupling to vibrational energy relaxation is shown to be negligible. A normal mode analysis of solute-to-solvent energy flux reveals an important role of high-frequency modes in the process of vibrational energy relaxation. Under all thermodynamic conditions considered they take part in solvent-assisted intramolecular energy redistribution and, moreover, at high pressure they considerably contribute to azulene-to-carbon dioxide energy flux. Solvent-assisted (or collision-induced) intermode energy exchange seems to be the main channel, ensuring fast intramolecular energy redistribution. For isolated azulene intramolecular energy redistribution is characterized by time scales from several to hundreds of ps and even longer, depending on initial excitation. The major part of solute vibrational energy is transferred to the solvent via solute out-of-plane vibrational modes. In-plane vibrational modes are of minor importance in this process. However, their contribution grows with solvent density. The distribution of energy fluxes via azulene normal modes strongly depends on thermodynamic conditions. The contribution of hydrogen atoms to the overall solute-to-solvent energy flux is approximately two to three times higher than of carbon atoms depending on the system and thermodynamic conditions as well. Carbon atoms transfer energy only in the direction perpendicular to the molecular plane of azulene, whereas hydrogen atoms show more isotropic behavior, especially at high pressure. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1520-4812
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The expressions for vibrational energy relaxation (VER) rates of polyatomic molecules in terms of equilibrium capacity time correlation functions (TCFs) derived in the first paper of this series [J. Chem. Phys. 110, 5273 (1999)] are used for the investigation of VER of azulene in carbon dioxide at low (3.2 MPa) and high (270 MPa) pressure. It is shown that for both cases the VER times evaluated on the basis of the same potential model via solute–solvent interaction capacity TCFs by means of equilibrium molecular dynamics (EMD) simulations satisfactorily agree with the nonequilibrium (NEMD) molecular dynamics [J. Chem. Phys. 110, 5286 (1999)] and experimental [J. Chem. Phys. 105, 3121 (1996)] results as well. Thus it follows that these methods can complement each other in characterizing VER from different points of view. Although more computational power and refined methods of dealing with simulated data are required for EMD simulations, they allow the use of powerful tools of equilibrium statistical mechanics for investigating the relaxation process. To this end, an analysis of VER mechanisms on the basis of normal mode and atomic representations is carried out. The influence of temperature and CO2 pressure on azulene normal mode spectra and solvent assisted intermode coupling in connection with the eigenvector structure is investigated in great detail. The normal mode capacity cross-correlation matrix reveals the significance of intermode coupling, which significantly contributes to intramolecular vibrational energy redistribution (IVR). As a new concept, partial normal mode relaxation rates are introduced. It is shown that these rates demonstrate similar properties as the energy exchange rates through particular normal modes in nonequilibrium simulations. Atomic spectra and friction coefficients are characterized by a complicated frequency dependence due to contributions from many normal modes. Atomic capacity TCFs and partial relaxation rates are analyzed and reveal a similar picture to that obtained from NEMD simulations. These results show that VER and IVR cannot be separated from each other and have to be considered as mutually connected processes. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 108 (1998), S. 10152-10161 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Results from nonequilibrium molecular-dynamics simulations of collisional energy transfer from vibrationally highly excited azulene in compressed CO2 are compared with experimental results from our laboratory obtained under comparable physical conditions. As observed in the experiment, the cooling rates show a purely monoexponential decay of the excess energy. The influence of the microscopic solvent shell structure on these processes is investigated using the full three-dimensional anisotropic CO2 structure around azulene obtained from the simulation. The analysis shows that local heating effects of any kind do not play a role in our model system. Predictions of the pressure dependence of the energy transfer rates by the isolated binary collision model are compared with results from the simulations using two different definitions of the collision frequency in dense fluids. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 7749-7755 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Molecular dynamic (MD) simulations of liquid CO2 at 250 MPa pressure and room temperature have been performed using a flexible model potential. A detailed analysis of the data reveal the full three-dimensional local structure of coordination shells that exhibit significant deviations from spherical symmetry with strong angular correlations among the molecules which form the inner coordination shell of the local liquid structure. Structures resembling T-shaped and offset-parallel CO2 dimers similar to those found in molecular beam and low temperature experiments have been identified, the T-shaped dimer having higher probability to be formed than the offset-parallel configuration. Local motion on short time scale is found to be different along three principal directions of a local coordinate frame. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...