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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neurosurgical review 4 (1981), S. 33-36 
    ISSN: 1437-2320
    Keywords: Craniocerebral injury ; CSF-fistula ; Posttraumatic fracture of the skull ; Depressed fracture ; Growing head injury ; Schädelhirntrauma ; Liquorfistel ; Posttraumatische Schädelfraktur ; Impressionsfraktur ; Wachsende Schädelfraktur
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ein ausgedehnter Tumor der Kopfschwarte bei einem 6 1/2jährigen Kind mit 5 Jahre zurückliegender Impressionsfraktur erwies sich mikroskopisch als Pseudotumor. Das Gewebe entsprach einem feingekammerten chronischen Hygrom mit Ausbildung von Strukturen nach Art Pacchionischer Granulationen. Es wird angenommen, daß die operativ nachgewiesene Liquorfistel zu einer entsprechenden Metaplasie des subkutanen und galealen Bindegewebes führte. Es bestand keine wachsende Fraktur.
    Notes: Summary A 6 1/2-year-old child, who had suffered a depressed fracture of the skull at the age of 1 1/2, had an extensive tumor of the scalp. Microscopic evaluation showed the growth to be a pseudotumor. The spongy tissue proved to be a chronic subdural hygroma containing structures resembling pacchionian granulations. A CSF fistula was demonstrated surgically. The fistula was assumed to be responsible for the metaplastic proliferation of subcutaneous and galeal connective tissue. A growing fracture was not present.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 69 (1998), S. 728-733 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Emigration ; Nationalsozialismus ; Schaltenbrand ; Menschenversuche ; Medizinische Ethik ; Key words Emigration ; National socialism ; Schaltenbrand ; Human experiments ; Medical ethics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary This review of German neurology during the Nazi era mentions first the significance of Jewish neurologists for the history of the specialty, and the irreplaceable loss that their expulsion from Germany represented. A brief discussion of the scientific accomplishments of German neurologists during this time is followed by a description of violations of ethical principles, exemplified by the human experiments of G. Schaltenbrand. The spirit of the age exerted a malevelent influence.
    Notes: Zusammenfassung In einem Rückblick auf die deutsche Neurologie während der Zeit des Nationalsozialismus wird auf die Bedeutung der jüdischen Fachkollegen für die Geschichte der Neurologie sowie auf den schweren Verlust durch die erzwungene Emigration hingewiesen. Darüber hinaus werden die wissenschaftlichen Leistungen während der NS-Zeit, aber auch die Verstöße gegen die ärztliche Ethik erwähnt, dies am Beispiel von Prof. G. Schaltenbrand. Die Bedeutung der bedenklichen Einflüsse eines Zeitgeistes wird hervorgehoben.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Nervenarzt 69 (1998), S. 99-109 
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Emigration ; Neuropathologie ; Nationalsozialismus ; Key words Emigration ; Neuropathology ; National Socialism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The paper reminds of the many psychiatrists, neurologists, and pathologists connected with scientific work in neuropathology who were expelled from Germany between 1933 and 1939 because of defamation by the Nuremberg Laws or because of their political opposition. Many of these colleagues saw their only way out as suicide. Short biographies give an orientation about the destiny of the expelled physicians in their host countries. The effort made after 1945 to give these emigrated colleagues again an adaequate position in Germany have not been very intensive.
    Notes: Zusammenfassung Die Arbeit erinnert an die zahlreichen der Neuropathologie verbundenen Psychiater, Neurologen und Pathologen, die zwischen 1933 und 1939 infolge der Diffamierung durch die Nürnberger Gesetze oder wegen politischer Verfolgung aus Deutschland in die Emigration fließen mußten oder einen Ausweg nur im Selbstmord sahen. Kurzbiographien orientieren über das Schicksal der Vertriebenen in ihren Gastländern. Hingewiesen wird aber auch auf die nur geringen Bemühungen, den Vertriebenen nach 1945 wieder eine ihren wissenschaftlichen Verdiensten entsprechende Position in Deutschland zu verschaffen.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 54 (1981), S. 165-167 
    ISSN: 1432-0533
    Keywords: Burkitt-type Lymphoma ; Collision tumor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A primary Burkitt-type lymphoma of the CNS was reported which developed in an 11-year-old boy 6 months after extirpation of an astrocytoma. Primary Burkitt-type lymphomas have been described only twice in the literature. The morphological aspect is interesting with regard to the problem of collision tumors.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 73 (1987), S. 361-364 
    ISSN: 1432-0533
    Keywords: Meningiomas ; Monoclonal antibody ; Proliferation potential
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 30 meningiomas we investigated the proliferation rate of various subtypes with the monoclonal antibody Ki-67. Frozen sections were incubated with Ki-67 antibody using a modified Alkaline Phosphatase anti-Alkaline Phosphatase (APAAP)-technique and evaluation of proliferation rate was done by cell counting. Meningiomas of the meningiotheliomatous, fibrous and angioblastic subtype without atypical histological findings contained 1% or less proliferating cells. In recurent tumors, in transitional and in anaplastic meningiomas there is a marked increase of proliferating cells up to 20%. The distribution of marked cells varies in recurrent tumors and anaplastic meningiomas, and a focal proliferation of tumor cells was seen in meningiomas from transitional type. Immunohistological labelling of proliferating cells in meningiomas may allow a more precise prediction of the proliferation potential of each meningioma.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 76 (1988), S. 245-252 
    ISSN: 1432-0533
    Keywords: Pleomorphic xanthoastrocytoma ; Fibrous xanthoma of the meninges ; Fibrous histocytoma ; Glial fibrillary acidic protein ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of a fibrous xanthomatous tumor of the meninges is reported. This is a rare tumor of childhood in which the characteristic pleomorphic histology contrasts with the good clinical prognosis [26]. These tumors were reclassified as pleomorphic xanthoastrocytomas (PXA) due to their glial fibrillary acidic protein (GFAP) positivity [27]. In the present tumor, GFAP was absent from nearly all cell bodies in most of the leptomeningeal regions of the tumor but could be detected with greater frequency at the cortical-leptomeningeal border zones and in the areas in which the tumor had infiltrated the cortex. All the tumor cells expressed vimentin and in, addition, most expressed α-1-antitrypsin, α-1-antichymotrypsin, tartrate-resistant acid phosphatase, common leukocyte antigen, and OKM1. This spectrum of marker staining corresponded not only to the pattern observed in two cutaneous fibrous histiocytomas and one malignant fibrous histiocytoma, but also to the results previously published in the literature with regard to fibrohistiocytic tumors. By contrast, this spectrum of monocytic-histiocytic marker staining was not seen in gliomas. We, therefore, regard the PXA as a mesenchymal tumor of the meninges, identical to benign fibrous histiocytomas elsewhere in the body. The possible reasons why this mesenchymal tumor can show GFAP positivity in the leptomeningeal border zone are discussed.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 84 (1992), S. 346-347 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0533
    Keywords: Creutzfeldt-Jakob disease ; Amyloid angiopathy ; Prion protein ; Immunohistochemistry ; Experimental transmission
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary It was difficult to make a definite pathological diagnosis in a 73-year-old man with Creutzfeldt-Jakob disease (CJD) due to extensive amyloid angiopathy which lacked any severe spongiform changes. Immunostaining using anti-prion protein (PrP) antibody revealed fine granular deposits in the gray matter, after hydrolytic autoclaving pretreatment on tissue sections. Western blotting also revealed an abnormal isoform of PrP, but PrP gene analysis did not show any abnormalities. The primary transmission experiments were repeated three times and induced spongiform encephalopathy in a few mice after a long incubation period.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 56 (1982), S. 87-92 
    ISSN: 1432-0533
    Keywords: Sträussler's disease ; Jakob Creutzfeldt's disease ; Subacute spongious encephalopathy ; Multicentric floccular plaques ; Slow virus disease ; Multiple sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A new family with the Gerstmann-Sträussler type of subacute spongiform encephalopathy is described. Atactic symptoms, dysarthrias, and personality changes characterized the clinical course. The clinical pattern of a father and his two sons was very similar. They had been in contact with sheep by occupation. A rapidly progressing demyelinating disease (transitional diffuse-multiple sclerosis) occurred in the same family, as well as numerous cases of carcinoma. Morphologically, the Sträussler type can be differentiated from other subacute spongy encephalopathies by the occurrence of Kuru-Plaques and numerous multicentric floccular plaques both in the cerebral and cerebellar cortex, basal ganglia, and white matter.
    Type of Medium: Electronic Resource
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