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  • 1
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 6 (1927), S. 1478-1478 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Lung 61 (1925), S. 504-508 
    ISSN: 1432-1750
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es gelingt, mit dem vonLanger angegebenen Impfstoff in der überwiegenden Anzahl der Fälle gegen Tuberkulin zu allergisieren. Versager lassen sich vermutlich auf zu lang gelagerten Impfstoff zurückführen. Damit werden die vonSelter erhobenen Einwände gegen dasLangersche Allergisierungsverfahren hinfällig. Gerade die langsam eintretende, ständig zunehmende Allergisierung spricht sehr für dieLangersche Methodik und rechtfertigt unseres Erachtens durchaus, gefährdete Säuglinge im ersten Lebensjahre mit dem ImpfstoffLangers zu immunisieren, zumal Schädigungen nicht zu erwarten sind. Dagegen führten Versuche, per os gegen Tuberkulin zu allergisieren, in der überwiegenden Mehrzahl der Fälle zu keinem irgendwie praktisch verwertbaren Ergebnis.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 41 (1926), S. 51-55 
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background and aim Atopic dermatitis (AD) is a common chronic inflammatory skin disease often accompanied by cutaneous Staphylococcus aureus colonization and, in this regard, especially complicated by the presence of superantigen-producing strains. Because IgG antibodies comprise an important defence mechanism of the adaptive immune system against bacteria, it was investigated whether AD patients have an abnormal pattern or distribution of superantigen-specific IgG subclass antibodies in association with disease severity and activity.Methods Staphylococcal enterotoxin B (SEB) and staphylococcal enterotoxin C1 (SEC1) specific IgG antibody subclasses were assessed in n=89 adult AD patients with mild to severe disease activity as determined by the SCORAD score and in n=28 healthy age-matched controls. Results were correlated with the current status of bacterial skin colonization and severity score.Results Thirty-eight per cent of the AD patients showed a selective deficiency in IgG2 antibodies against SEC1 compared with only 14% in the control group. The absence of these antibodies was found in both currently colonized and non-colonized AD patients and was associated with a severe phenotype (SCORAD more than 40 points in two-thirds of the deficient patients). However, these patients had normal production levels of IgG2 antibodies against pneumococcal capsular polysaccharide (PCP) and SEB, but higher IgG1 and IgG4 titres against SEC1. Except for elevated total IgG1, total IgG subclass levels were normal in this AD subgroup. Yet, peripheral blood mononuclear cells (PBMCs) derived from these patients clearly produced IL-4 and IL-5 upon SEC1 re-stimulation whereas PBMCs from those providing SEC1-specific IgG2 antibodies failed in the production of these cytokines.Conclusion A subgroup of AD patients suffers from a selective deficiency to produce anti-SEC1 IgG2 antibodies. This patient group is characterized by a severe AD phenotype.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial and engineering chemistry 7 (1968), S. 165-169 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial and engineering chemistry 8 (1969), S. 197-198 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1435-1536
    Keywords: Wool ; nonkeratinous proteins ; enzymatic hydrolysis ; pronaseE ; extent of digestion ; (α + ε)-aminogroups ; microbial investigations ; fractionating of the keratoses ; internal volume ; mercury porosimetry ; centrifugal swelling test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The nonkeratinous proteins of wool can be partly or completely dissolved by controlled enzymatic digestion. A comparison between the keratose content of intact wool and that of wool which has been hydrolysed for 96 h with pronase confirms that specifically all the nonkeratinous components are dissolved out of the wool composite by pronase. The influence of microbial infection can be excluded. The residue of wool after the hydrolysis, i. e., a wool low in nonkeratinous proteins, has a higher internal volume, as measured by mercury porosimetry. The centrifugal swelling test shows that these wool samples also have increased hygroscopy.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1173
    Keywords: Schlüsselwörter UV-Schutzfaktor ; Kleidung ; Sonnenschutz ; Prävention ; Key words Fabrics ; Clothes ; Sun protection ; Prevention ; Skin cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A rising incidence worldwide of skin cancer has been observed for years. A high cumulative exposure to UV radiation is a major factor in the development of such neoplasms. Suitable protective measures are therefore becoming increasingly important. Textiles provide simple, effective and medically safe protection against UV radiation. At present, however, in Europe – in contrat to Australia – the UV protection factor (UPF) for summer textiles is not stated. It is a largely unknown fact that by far not all textiles offer sufficient protection. Our goal was to study the factors which determine the UV transmission of fabrics and, based on these findings, to design materials which provide enhanced protection. A spectrophotometric method was used to determine the UV transmission by fabrics made of cotton, silk, polyester and viscose. The UV protection factors of the fabrics were computed on the basis of the transmission data. The UV protection factor is dependent on the type of fibre, yarn and surface design, weight per square metre, moisture content, colour, finishing method and degree of wear. To optimize the UV protection via textiles, a viscose yarn with a low UV transmission was used. This yarn makes it possible to design light-weight summer fabrics with optimized UV protection. This development will make it possible to offer clothing with high UV protection on the European marked. This clothing will not be more expensive than normal products, so that effective prevention should be more available.
    Notes: Zusammenfassung Seit Jahren wird ein weltweiter Anstieg der Hautkrebsinzidenz beobachtet. Eine hohe kumulative UV-Strahlenexposition gilt als ein Hauptfaktor für die Entstehung von Neoplasien der Haut. Geeignete Schutzmaßnahmen gewinnen daher zunehmend an Bedeutung. Textilien bieten eine einfachen und effektiven, medizinisch unbedenklichen Schutz vor der UV-Strahlung, doch wird der UV-Schutzfaktor (USF) von Sommertextilien, z.Z. in Europa – im Gegensatz zu Australien – nicht angegeben.Weitgehend unbekannt ist in diesem Zusammenhang, daß bei weitem nicht alle Textilien einen ausreichenden Schutz bieten. Ziel ist, die Faktoren, welche die UV-Durchlässigkeit von Stoffen bestimmen, zu untersuchen und ausgehend von diesen Ergebnissen Materialien mit verbessertem Schutz zu konstruieren. Die UV-Durchlässigkeit wurde an Geweben aus Baumwolle, Seide, Polyester und Viskose mit einer spektralphotometrischen Methode bestimmt. Die UV-Schutzfaktoren der Stoffe wurden aus den Transmissionsdaten berechnet. Anhand der Ergebnisse konnte gezeigt werden, daß UV-Schutzfaktor von der Faserart, der Garn- und Flächenkonstruktion, dem Quadratmetergewicht, dem Feuchtegehalt, der Färbung, der Ausrüstung und der Abnutzung durch den Gebrauch der Stoffe abhängt. Zur Optimierung des UV-Schutzes durch Stoffe wurde erstmals ein Viskosegarn mit einer extrem geringen UV-Durchlässigkeit eingesetzt. Dieses Garn ermöglicht es, leichte Sommerstoffe mit optimiertem UV-Schutz zu konstruieren. Zukünftig wird es damit möglich sein, Kleidung mit einem hohen UV-Schutzfaktor anzubieten. Diese Kleidung wird nicht teurer sein als normale Produkte, so daß eine hohe Effektivität für unsere Präventionsbemühungen erwartet werden kann.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 7 (1928), S. 118-119 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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