Note: Intro -- Preface -- Contents -- About the Authors -- 1 Fundamentals of Ion Beam Technology, Waveguides, and Nanoparticle Systems -- 1.1 Ion Beam Technology Applied for Optical Dielectrics -- 1.1.1 The Ion Beam Facilities -- 1.1.2 The Ion Beam Techniques -- 1.2 Optical Dielectric Waveguides -- 1.3 Optical Properties of Nanoparticle Systems -- 1.4 Techniques for Investigation of Photonic Devices -- 1.4.1 Optical Coupling of Waveguides -- 1.4.2 Microscopic and Spectroscopic Investigations of Waveguides -- References -- 2 Overview of Ion Beam Produced Dielectric Waveguides -- 2.1 Overview of Dielectric Materials for Waveguide Fabrication -- 2.1.1 Glasses -- 2.1.2 Crystals -- 2.1.3 Ceramics -- 2.2 Refractive Index Profiles -- 2.3 Fabrication Techniques and Waveguide Geometries -- 2.4 Basic Waveguiding Properties -- References -- 3 Photonic Structures Based on Thin Films Produced by Ion Beams -- 3.1 Freestanding Crystalline Thin Films by Crystal Ion Slicing -- 3.2 Direct Bonding of Crystalline Membranes on Insulators by LNOI Technology -- 3.3 Micro-/Nano-structuring of LNOI On-Chip Waveguides -- 3.4 LNOI On-Chip Whispering-Gallery Resonators -- 3.5 LNOI On-Chip Photonic Crystal Based Structures -- 3.6 LNOI On-Chip Optical Couplers/Interfaces -- References -- 4 Nanoparticles Synthesized by Ion Implantation -- 4.1 Formation of Elemental Nanoparticles -- 4.1.1 Charge States of Implants in Solids -- 4.1.2 Nucleation, Growth, and Nonmetal-Metal Transition of Metallic Nanoparticles -- 4.1.3 Nucleation Threshold and Control -- 4.1.4 Very Small Non-metallic Metal Nanoparticles as Luminescence Sensitizers -- 4.1.5 Miscellaneous -- 4.2 Semiconductor and Compound Nanoparticles -- 4.2.1 Elemental Semiconductor Nanoparticles -- 4.2.2 Compound Semiconductor Nanoparticles -- 4.3 Oxide Nanoparticles -- 4.4 Amorphous and Liquid Nanoparticles. , 4.4.1 Amorphous Nanoparticles -- 4.4.2 Molten Nanoparticles -- 4.5 Metal Nanoparticles with Two or More Resonances -- 4.6 Magnetic Nanoparticles and Magneto-Optical Effects -- 4.6.1 Superparamagnetic Nanoparticles -- 4.6.2 Magneto-Optical Kerr Effect -- 4.6.3 Curie Transition Modified by the Finite-Size Effect in Magnetic Nanoparticles -- 4.7 Some Phenomena to Be Noted -- 4.7.1 Inter-particle Interaction Between Nanoparticles and Appearance of a New Band -- 4.7.2 High Flux Implantation Effects -- 4.7.3 Laser Co-irradiation Effects on Nanoparticle Formation -- 4.7.4 Single Electron Tunneling to Nanoparticles Embedded in Insulator -- 4.7.5 Cavity Nanoparticles, Sandwiched Nanoparticles, and Nanoplanets -- 4.7.6 Catalysis Nanoparticles -- References -- 5 Shape Elongation of Nanoparticles Induced by Swift Heavy Ion Irradiation -- 5.1 Ion Irradiation Effects on Amorphous Silica -- 5.1.1 Optical Absorption of Point Defects -- 5.1.2 Ion Tracks -- 5.1.3 Compaction -- 5.1.4 Microscopic Origin of Compaction and Core/Shell Ion Tracks -- 5.1.5 Inelastic Thermal Spike Model for the Core/Shell Track Formation and Inconsistency -- 5.1.6 Ion Hammering -- 5.2 Shape Elongation of Nanoparticles -- 5.2.1 Observations of the Shape Elongation of Nanoparticles -- 5.2.2 Minimum Width for the Elongation -- 5.2.3 Particle-in-Vacuum Model -- 5.2.4 Mass Non-conservation of Nano-Rods -- 5.2.5 Initial Nanoparticle Size Dependence on the Elongation -- 5.2.6 Scaling Law for the Elongation -- 5.3 Mechanism of Shape Elongation -- 5.3.1 Inelastic Thermal Spike -- 5.3.2 Two-Temperature Molecular Dynamics -- 5.3.3 Criticisms on Synergy Model Based on Ion Hammering -- 5.4 Optical Properties of Elongated Nanoparticles -- 5.4.1 Optical Linear Dichroism -- 5.4.2 Birefringence -- 5.4.3 Possible Application to UV Polarizer of Nanometric Thickness -- 5.4.4 Second-Harmonic Generation Microscopy. , 5.4.5 Electron Energy Loss Mapping of Elongated Nanoparticles -- 5.5 Some Comments Related to Track Formation -- 5.5.1 Primary Ionization Rate and Velocity Effect Free Theory -- 5.5.2 Self-trapped Exciton Model Versus Exciton Mott Transition and Thermal Spike Heating -- 5.5.3 Recrystallization of Ion Tracks -- 5.6 Elongation by Cluster Irradiation-Toward Lower Energy and More Accessibility -- References -- 6 Electrooptic Properties of Dielectric Waveguides -- 6.1 Modification of Electrooptic Coefficients of Dielectrics -- 6.2 Electrooptic Modulators on Waveguides -- 6.3 Electrooptic Modulators on Membrane -- 6.4 Electrooptic Modulators on LNOI Waveguides -- 6.4.1 EO Phase Modulator Based on Straight Waveguide (Fabry-Perot) Resonator -- 6.4.2 EO Tunable Microring Resonators -- 6.4.3 EO Mach-Zehnder Interferometer Resonators -- 6.4.4 EO Tunable LNOI Bragg Reflectors -- 6.4.5 Compact EO Fourier Transform Spectrometers -- References -- 7 Photoluminescence of Dielectric Waveguides -- 7.1 Up-Conversion of Waveguides -- 7.2 Near Infrared Luminescence in Waveguides -- 7.2.1 Doped LiNbO3 Crystals -- 7.2.2 Doped YAG Crystals -- 7.2.3 Other Crystals -- 7.3 Waveguide Amplifiers -- References -- 8 Nonlinear Optical Dielectric Waveguides -- 8.1 Nonlinear Optical Properties of Waveguides -- 8.2 Nonlinear Frequency Conversion Based on Waveguides -- 8.3 Photorefractive Waveguides -- 8.4 Discrete Solitons in Waveguides and Waveguide Arrays -- References -- 9 Lasing Based on Dielectric Waveguides -- 9.1 Waveguide Lasing at Near Infrared Wavelength Regimes -- 9.2 Pulsed Waveguide Lasers Based on 2D Materials -- 9.3 Self-Frequency Doubled Waveguide Lasing -- References -- 10 Tailoring of Optical Properties by Metallic Nanoparticles -- 10.1 Optical Absorbance Enhancement by Surface Plasmon Resonance -- 10.2 Giant Enhancement of Optical Nonlinearities. , 10.3 Nonlinear Absorption Tuning by Nanoparticles -- 10.4 Pulsed Waveguide Lasers Based on Nanoparticles as Saturable Absorbers -- References -- 11 Summary and Outlook -- 11.1 Summary -- 11.2 Outlook -- 11.2.1 New Materials -- 11.2.2 Novel Devices for Micro-nano Photonics -- Index.

Note: Intro -- Title Page -- Copyright -- Contents -- Preface -- Index.

Note: Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Contents -- About the Editors -- List of Contributors -- 1. Introduction -- 2. Complex Innovative Design -- 3. Validation Strategy for Biomarker-Guided Precision/Personalized Medicine -- 4. Model-Informed Drug Development -- 5. Real-World Data and Real-World Evidence -- 6. AI/ML in Medical Research and Drug Development -- 7. Challenges in Cancer Clinical Trials -- 8. Statistical Methods for Assessment of Biosimilars -- 9. Statistical Methods for Assessment of Complex Generic Drugs -- 10. Rare Diseases Drug Development -- Index.