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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Electroanalytical Chemistry 350 (1993), S. 279-295 
    ISSN: 0022-0728
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Electroanalytical Chemistry 350 (1993), S. 297-316 
    ISSN: 0022-0728
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Phytochemistry 20 (1981), S. 2772-2773 
    ISSN: 0031-9422
    Keywords: Compositae ; Inuleae ; Pulicaria gnaphalodes ; clerodane derivative. ; diterpene lactone
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 6 (1991), S. 363-366 
    ISSN: 1435-604X
    Keywords: Laser vascular welding ; Tissue fusion ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The central problem in microsurgery is the reconstruction of small vessels. The long operating time, foreign body granuloma formation around the suture material as well as aneurysmal alterations of the vessel wall after conventional suture technique make the search for alternatives indispensable. Some of these disadvantages can be avoided as demonstrated by our animal experiments and histological examinations in laser-assisted anastomosing. The aim of this study is to show these aspects in connection with laser application and compare them with conventional suture techniques.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1435-2451
    Keywords: Ventricular Septal Defect ; Bland Chest Trauma ; Ventrikelseptumdefekt ; Stumpfes Thoraxtrauma ; Comotio cordis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Traumatisch bedingte Ventrikelseptumrupturen nach stumpfen Thoraxtraumen sind als Seltenheit anzusehen. Einem 19jährigen Studenten war während der Arbeit beim Entladen eines LKW eine 30 kg schwere Kiste auf den Brustkorb gefallen. Bei der Aufnahme bestand ein kardiogener Schock and über dem Herzen war ein lautes systolisches Geräusch zu hören. 6 Std nach dem Unfall konnte der Septumdefekt durch einen Teflonpatch verschlossen werden. Postoperativ kam es zu einer Anurie, bedingt durch den schweren prä-operativen Schock. Der Patient verstarb am 11. postoperativen Tag am akuten Nierenversagen und einer Bronchopneumonie.
    Notes: Summary This report concerns the case of a 19-year-old student who developed a loud systolic murmur over the precordium and signs of venous inflow obstruction following a bland chest trauma. The diagnosis of a traumatic VSD was confirmed by right- and transseptal left heart catheterization. The patient was operated upon 6 h after the accident with the aid of a cardiopulmonary By-pass. The defect was 1.5 cm in diameter and was located within the membranous part of the septum. Postoperatively the patient developed acute renal failure, which was most probably related to the state of shock which had been present before the operation. He died 11 days after surgery. The terminal event was bilateral pneumonia.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 339 (1975), S. 721-721 
    ISSN: 1435-2451
    Keywords: Prosthesis: Heart valve ; Thrombosis, of valve ; Insufficiency, of valve ; Herzklappenprothese ; Thrombose ; Funktionsstörung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1962–1975 wurden in der Chirurgischen Universitätsklinik Heidelberg 815 Herzklappenprothesen implantiert. 474 Aortenklappen und 341 Mitralklappen, einschließlich 70 Doppelklappen wurden ersetzt. 22 Patienten (3%) mußten wegen einer Funktionsstörung der Prothese reoperiert werden. 19 Aortenklappen (3 Cross-Jones-, 16 Starr-Edwards-Prothesen) und 3 Mitralklappen (Cross-Jones) mußten wegen ausgerissener Fäden refixiert, wegen Thrombosierung oder defekter Scheiben ausgewechselt werden. Die häufigsten Komplikationen der gestörten Klappenfunktion waren: Herzinsuffizienz, Hämolyse und periphere Embolien. 7 Patienten sind verstorben. 4mal an Herzinsuffizienz, 2mal am Nierenversagen und 1mal an einer Hirnembolie.
    Notes: Summary In the Department of Surgery at the University of Heidelberg, 815 prosthetic heart-valve replacements were carried out from 1962 to 1975, 474 of aortic valves and 341 of mitral valves, including 70 double valve replacements. Twenty-two patients (3%) needed second operations due to insufficiency of the prothetic valve. In these 22 patients, 19 aortic valves (3 Cross-Jones and 16 Starr-Edwards prostheses) and 3 mitral valves (Cross-Jones) had to be refixed or changed due to thrombosis or a defect of the valve. The most common clinical complications of these valve malfunctions were: Cardiac insufficiency, hemolysis, and peripheral embolism. There were 7 deaths: 4 due to cardiac insufficiency, 2 due to renal failure and 1 due to brain embolism.
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  • 7
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In Form von 4 Tierversuchen (Kälber) wird eine in vitro an Rinder-, Kälber- und Schafsherzen erarbeitete Methodik zur röntgenologischen Darstellung des RSL des Herzens bezüglich ihrer in-vivo-Tolerabilität erprobt. Klinisch kann die in-vivo-Tolerabilität grundsätzlich nachgewiesen werden; wir müssen jedoch betonen, daß durch die Verwendung hypertonischer Röntgenkontrastmittel Veränderungen im Bereich der Mikro- und Ultrastrukturen der RLS-Zellen induziert werden können, deren Dignität momentan nicht sicher eingestuft werden kann.
    Notes: Summary A method for radiological presentation of the left ventricular conduction system was tested for in-vivo tolerability. In-vivo tolerability could be demonstrated clinically; however, we should emphasize that hypertonic X-ray contrast dyes may cause morphological changes of unknown significance in the micro- and ultrastructures of the specialized musculature.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Diskutiert wird der Fall einer 28jährigen Motorradfahrerin, die bei einem Unfall in das Speichenrad ihres Fahrzeuges geraten war. Es resultierte eine ausgedehnte Weichteilverletzung des Mittel- und Rückfußes, eine Defektfraktur des Calcaneus, ein knöcherner Abriß der Achillessehne, eine Außenknöchelfraktur Weber A und eine Metatarsale II-Fraktur. Die Primärversorgung erfolgte in folgender Weise: Ausgedehntes Debridement der stark verschmutzten Weichteile, Refixation der Achillessehne am Calcaneus mit zwei Osteosyntheseschrauben. Die noch erhaltenen, jedoch kontusionierten Hautlappen wurden spannungsfrei adaptiert. Dies war allerdings nur in einer erheblichen Spitzfußstellung möglich. Im weiteren Verlauf kam es zu einer ausgedehnten Haut- und Weichteilnekrose über dem Rückfuß. Um einen belastungsfähigen Rückfuß zu erhalten, eine Calcaneusosteitis abzuwenden, die Spitzfußstellung auszugleichen Bowie eine Resensibilisierung in der Belastungszone der Fußsohle zu erzielen, wurde ein neurovaskulär gestielter Unterarmlappen frei übertragen. Es kam zu einem guten Einheilungsergebnis, die Spitzfußstellung wurde weitgehend ausgeglichen, die Calcaneusosteitis abgewendet, und die Funktion der Achillessehne blieb erhalten. Darüber hinaus kam es zu einer befriedigenden Resensibilisierung des Rückfußes, so daß die Patientin heute in der Lage ist, in Konfektionsschuhen mit einer umfassend gewalkten Einlage zu laufen.
    Notes: Summary A discussion is presented on the case of a 28-year-old motorcyclist who had an accident and got caught in the spoked wheel of her vehicle. The result was an extensive soft-tissue injury of the metatarsus and calcaneal part of the foot, a defect fracture of the calcaneus, an osseous disinsertion of the Achilles tendon, a lateral malleolus Weber type-A fracture, and a fracture of the second metatarsal bone. The primary treatment consisted in extensive débridement of the strongly contaminated soft parts and refixation of the Achilles tendon on the calcaneus with two osteosynthesis screws. The bruised skin flaps remaining were adapted in a tension-free manner. However, this was possible only in a considerable talipes equinus position. In the further course, the patient developed an extensive skin and soft-tissue necrosis over the calcaneal part of the foot. A neurovascularly pedicled forearm flap was freely grafted in order to maintain the load capacity of the calcaneal part of the foot, to prevent osteitis of the calcaneus, to correct the talipes eqinus position, and to achieve a resensibilization in the load zone of the sole. The healing result was good, and it was possible to achieve extensive correction of the talipes equinus position as well as prevention of calcaneus osteitis; the function of the Achilles tendon was also maintained. Moreover, there was satisfactory resensibilization of the calcaneal part of the foot, so that the patient can now walk in ready-made shoes with a fully molded arch support.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of assisted reproduction and genetics 13 (1996), S. 647-651 
    ISSN: 1573-7330
    Keywords: hamster-intracytoplasmic sperm injection assay ; human sperm ; severe male factor ; zona-free hamster penetration test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Our objective was to investigate the fertilizing ability of human sperm from severe male-factor patients, by microinjection of single sperm into the hamster oocyte. Design: Semen samples of severe male factor either with a 0% penetration rate in the zona-free hamster test or with a very low number of motile sperm for which performing the standard penetration test was impossible were used. For the control study, oligozoospermic semen samples with at least 10% penetration rate in zona free hamster test were used. Setting: All materials were collected from the National University Hospital, Singapore. Methods: There were 10 patients in both the experimental and the control groups. Intracytoplasmic sperm injection (ICSI) was carried out. The main outcome measures were sperm head decondensation and pronuclear formation. Results: Twenty-one percent of the injected sperm could decondense and undergo male pronuclear formation. This rate was not significantly different from that in the control study group (28%; P=0.13). A small proportion of the oocytes was damaged during the procedure (9.2 and 8.75% in experimental and control groups, respectively). Conclusions: Hamster-ICSI assay may be of benefit in predicting the sperm's ability for further development before allowing the patient to undergo the clinical program.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 349 (1979), S. 561-561 
    ISSN: 1435-2451
    Keywords: Antibiotic prophylaxis ; Cardiac surgery ; Antibioticaprophylaxe ; Herzchirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 34 Patienten wurde während kardiochirurgischer Eingriffe in EKZ nach Gabe von Cephradin 1 g oder Cefamandol 2 g vor Op.-Beginn Plasma sowie verschiedene Gewebsspiegel zu unterschiedlichen Zeitpunkten bestimmt und in Beziehung zur minimalen Hemmkonzentration gegenüber Staph. aur. und Staph.epid. gesetzt: Die Konzentration im bradytropen Herzklappengewebe lag deutlich höher als im Muskelu. Subcutangewebe. Es waren mindestens über 90 min therapeutisch wirksame Antibiotica-Spiegel nachzuweisen. Diese Antibiotica-Abschirmung sollte lediglich als Kurzzeit-Prophylaxe von 24–48h fortgeführt werden.
    Notes: Summary During cardiac surgery with ECC on 34 patients the plasma and various tissue concentrations were measured after application of Cephradin 1 g or Cephamandol 2 g at the beginning of the operation and at various intervals thereafter. Tissue levels were set in relation to the minimal inhibitory concentration against Staph. aur. and Staph. epid.: The concentrations were higher in the bradytrophic cardiac valve tissue than in muscle or subcutaneous tissue. Therapeutic antibiotic levels were noted for at least 90 min. Antibiotic protection should only be continued for 24–48 h.
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