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  • 1
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    Effects of CO2-driven ocean acidification on early life stages of marine medaka (Oryzias melastigma) (2015)
    PANGAEA
    In:  Supplement to: Mu, J; Jin, F; Wang, J Y; Zheng, N; Cong, Y (2015): Effects of CO2-driven ocean acidification on early life stages of marine medaka (Oryzias melastigma). Biogeosciences, 12(12), 3861-3868, https://doi.org/10.5194/bg-12-3861-2015
    Details
    Publication Date: 2024-03-15
    Description: The potential effects of elevated CO2 level and reduced carbonate saturation state in marine environment on fishes and other non-calcified organisms are still poorly known. In present study, we investigated the effects of ocean acidification on embryogenesis and organogenesis of newly hatched larvae of marine medaka (Oryzias melastigma) after 21 d exposure of eggs to different artificially acidified seawater (pH 7.6 and 7.2, respectively), and compared with those in control group (pH 8.2). Results showed that CO2-driven seawater acidification (pH 7.6 and 7.2) had no detectable effect on hatching time, hatching rate, and heart rate of embryos. However, the deformity rate of larvae in pH 7.2 treatment was significantly higher than that in control treatment. The left and right sagitta areas did not differ significantly from each other in each treatment. However, the mean sagitta area of larvae in pH 7.6 treatment was significantly smaller than that in the control (p = 0.024). These results suggest that although marine medaka might be more tolerant of elevated CO2 than some other fishes, the effect of elevated CO2 level on the calcification of otolith is likely to be the most susceptibly physiological process of pH regulation in early life stage of marine medaka.
    Keywords: Alkalinity, total; Animalia; Aragonite saturation state; Aragonite saturation state, standard deviation; Behaviour; Bicarbonate ion; Bicarbonate ion, standard deviation; Bottles or small containers/Aquaria (〈20 L); Calcite saturation state; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbon, inorganic, dissolved, standard deviation; Carbonate ion; Carbonate ion, standard deviation; Carbonate system computation flag; Carbon dioxide; Carbon dioxide, standard deviation; Chordata; Coulometric titration; Development; Figure; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Growth/Morphology; Hatching rate; Hatching rate, standard deviation; Hatching time; Hatching time, standard deviation; Heart rate; Heart rate, standard deviation; Laboratory experiment; Laboratory strains; Larval deformity rate; Larval deformity rate, standard deviation; Mortality/Survival; Nekton; Not applicable; OA-ICC; Ocean Acidification International Coordination Centre; Oryzias melastigma; Otolith area; Otolith area, standard deviation; Oxygen; Oxygen, standard deviation; Partial pressure of carbon dioxide, standard deviation; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Pelagos; pH; pH, standard deviation; Potentiometric; Reproduction; Salinity; Salinity, standard deviation; Single species; Species; Survival; Survival rate, standard deviation; Temperature, water; Temperature, water, standard deviation; Treatment
    Type: Dataset
    Format: text/tab-separated-values, 345 data points
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    DATA PANGAEA
  • 2
    Electronic Resource
    Electronic Resource
    Scanning tunneling microscopy of an ion-bombarded PbS(001) surface (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 2039-2041 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Freshly cleaved (001) surfaces of single crystalline PbS were bombarded by 8 keV Kr+ ions at a dose of 3×1012 cm−2. Atomically resolved scanning tunneling microscopy (STM) images were taken showing damaged areas due to individual ion impacts. Analysis of a STM image shows a shallow impact crater, a stacking fault, displacement of Pb2+ and S2− ions from their regular surface sites, and migration of interstitials to the surface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.100312
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    catena-Poly[[tetrakis(imidazole-N3)copper(II)]-μ-(dichromato-O:O')] (1998)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 1802-1804 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270198006660
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Poly[mercury(II)-μ-4,4'-bipyridine-di-μ-bromo] (1999)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 343-345 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270198006325
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Surface analytical investigations on the oxidation behaviour of TiAl-base intermetallics (1993)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 346 (1993), S. 75-78 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The oxidation behaviour of TiAl-base intermetallics has been investigated at 800°C in air. The main emphasis was placed on the mechanism by which niobium additions decrease the oxidation rate of titanium aluminides. For this purpose specimens of Ti50Al and Ti45Al10Nb were oxidized in a two-stage oxidation technique using an 18O-tracer. The scale formed during this oxidation process was analyzed by SNMS. It was found that niobium is mainly incorporated in the titanium dioxide and the nitride scale which forms beneath the initially formed alumina layer. The effect of this behaviour of the niobium on the oxide scale growth rates is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00321386
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    Paper (German National Licenses)
    Fulltext
  • 6
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    GNSS dual-frequency carrier phase multipath MHM model and its application in real deformation monitoring scenario (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-06-19
    Description: The GNSS multipath delay error is highly related to the surrounding monitoring environment, which cannot be eliminated or mitigated by establishing the double difference observation model. In the actual monitoring environment, due to the complexity of the multi-GNSS constellation, it is difficult for existing algorithms to consider GEO, IGSO, MEO and other different orbital types of satellites for real-time and efficient multipath error reduction. Therefore, this paper proposes a novel GNSS dual-frequency multipath error reduction method for real deformation monitoring for GNSS considering various satellite orbit types. This method extracts the single error residual of each satellite based on the assumption of "zero mean", and divides the appropriate grid density of GEO and IGSO\MEO respectively, to construct the dual-frequency multi-path hemispherical map model suitable forGNSS satellites with different orbital types. This method can realize the multi-path error elimination of the observed values of different orbits and different frequencies. The results of simulation experiments and real deformation monitoring data demonstrate that this method can effectively eliminate low-frequency multipath delay errors in the observation domain and coordinate domain. After multipath correction, the precision of the horizontal coordinates and height coordinates is 1.7mm and 4.6mm. The precision of the horizontal coordinate and height coordinate is increased by 50% and 60% respectively. The fixed rate of ambiguity increased by 5%~7%.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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    GFZ OAI
  • 7
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    Space resources exploration and utilization – A geodetic perspective (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-09-12
    Description: The exploration and utilization of space resources is a new wave of international interest. The US Space Resource Exploration and Utilization Act in 2015 was a tipping point for the accelerated process of new space competition. The primary purpose of extra-terrestrial mining is to search for minerals, elements and water from asteroids and minor planets that are close to the Earth. Geospatial science and technology, geodesy and remote sensing in particular, plays a critical role in this huge space mining systematic engineering endeavor, as is the case of surveying for large engineering projects. This contribution argues that the combination of mining and geospatial technology is a “must” in the early stage of space endeavor of resources exploration and utilization. The current status of space mining from a geodetic perspective and the potential targets of space resources exploration are presented. It is concluded that, based on the current level of scientific and technological development and the potential value of known space resources, mining the near-Earth asteroids as the first step is feasible and will be one of the major trends of space resources exploration and an important part of space economy. The priorities of space mining that need urgent attention are identified, which includes but not limited to space resources exploitation, space intelligent robots related design and manufacture, prospecting and mining of space resources, safety and in-situ utilization of space resources. Meanwhile, the vision of space mining development in China has been constructed.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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    GFZ OAI
  • 8
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    The next wave of GNSS tropospheric sounding – perspective and retrospective (2023)
    In:  XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)
    Details
    Publication Date: 2023-09-12
    Description: As one of the most important parameters, water vapor is very valuable for the studies of extreme weather events and climatic phenomena. The GNSS have been proven to be a relatively new technique for sounding atmospheric water vapor which has experienced unprecedented developments over the past decade due to the rapid deployment of wide-spread space- and ground-based infrastructures. This significant development and the long-term accumulation of GNSS data, has offered a strong data support and new opportunity to advance our understanding of climate change and extreme weather events. In the meanwhile, the fifth resurgence of artificial intelligence (AI) technology has empowered us in the ability of big geodetic data analytics and data mining. All these have helped us in the understanding the atmospheric dynamic process, and mining the detailed information of the formation, evolution, development and dissolution of extreme weather events and complicated atmospheric process. This contribution presents a summary of our 10-year relevant research in the area that involves a full spatial domain of ground-, air- and space-based systems and a comprehensive technological domain of GNSS/geodesy, remote sensing, meteorology and atmosphere. First, the background, current status and recent international frontier developments of the GNSS tropospheric sounding technique are summarized. Then, the theory, technical features and major advancement of the GNSS-derived atmospheric products in the applications of climate analyses and extreme weather forecasting are presented. Finally, the challenges, opportunities and future prospectives in terms of the technique and its innovative applications of national and international significance are provided.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 9
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    KEAP1 Mutations Impair NRF2 Degradation, Not Ubiquitination (2014)
    The American Association for Cancer Research (AACR)
    Details
    Publication Date: 2014-02-04
    Description: NRF2 is a transcription factor that mediates stress responses. Oncogenic mutations in NRF2 localize to one of its two binding interfaces with KEAP1, an E3 ubiquitin ligase that promotes proteasome-dependent degradation of NRF2. Somatic mutations in KEAP1 occur commonly in human cancer, where KEAP1 may function as a tumor suppressor. These mutations distribute throughout the KEAP1 protein but little is known about their functional impact. In this study, we characterized 18 KEAP1 mutations defined in a lung squamous cell carcinoma tumor set. Four mutations behaved as wild-type KEAP1, thus are likely passenger events. R554Q, W544C, N469fs, P318fs, and G333C mutations attenuated binding and suppression of NRF2 activity. The remaining mutations exhibited hypomorphic suppression of NRF2, binding both NRF2 and CUL3. Proteomic analysis revealed that the R320Q, R470C, G423V, D422N, G186R, S243C, and V155F mutations augmented the binding of KEAP1 and NRF2. Intriguingly, these “super-binder” mutants exhibited reduced degradation of NRF2. Cell-based and in vitro biochemical analyses demonstrated that despite its inability to suppress NRF2 activity, the R320Q “superbinder” mutant maintained the ability to ubiquitinate NRF2. These data strengthen the genetic interactions between KEAP1 and NRF2 in cancer and provide new insight into KEAP1 mechanics. Cancer Res; 74(3); 808–17. ©2013 AACR.
    Print ISSN: 0008-5472
    Electronic ISSN: 1538-7445
    Topics: Medicine
    Published by The American Association for Cancer Research (AACR)
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    PAPER CURRENT
  • 10
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    Sodium permeation in bacterial Nav channel [Biophysics and Computational Biology] (2013)
    National Academy of Sciences
    Details
    Publication Date: 2013-07-10
    Description: Determination of a high-resolution 3D structure of voltage-gated sodium channel NaVAb opens the way to elucidating the mechanism of ion conductance and selectivity. To examine permeation of Na+ through the selectivity filter of the channel, we performed large-scale molecular dynamics simulations of NaVAb in an explicit, hydrated lipid bilayer at...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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    PAPER CURRENT
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