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  • 1
    Electronic Resource
    Electronic Resource
    Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors (1995)
    [s.l.] : Nature Publishing Group
    Nature 376 (1995), S. 514-516 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Oocytes were injected with mRNA for wild-type subunits or for subunits containing the Leu 9'Ser mutation; the latter are denoted here with an asterisk. Figure 1 shows raw traces and dose-response data for nAChRs that exemplify combinations for mf = 1, 2, 3 and 4 Leu 9'Ser mutations, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/376514a0
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    Paper (German National Licenses)
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  • 2
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    Selecting the reference image for registration of CEST series (2015)
    Wiley-Blackwell
    Details
    Publication Date: 2015-08-14
    Description: Background To compare different reference images selected for registration among chemical exchange saturation transfer (CEST) series. Materials and Methods Five normal volunteers and eight brain tumor patients were studied on a 3 Tesla scanner. Image registration was performed by choosing each of the acquired CEST saturation or unsaturation dynamic images as the reference. CEST images at 3.5 ppm (amide proton transfer, APT) were computed for each motion-corrected data set after main magnetic field inhomogeneity correction. A uniformity index was defined to quantify the efficacy of image registration using different reference images. Joint histograms and the structural similarity index (SSIM) were used to analyze the intrinsic image similarity between various dynamic images. Results Image registration increased the average uniformity index by 18% if the 3.5 ppm saturated image was selected as the reference image. However, registering to the unsaturated dynamic image reduced the uniformity index by 13% on average. The joint histogram analysis showed that the saturated dynamic images were highly similar (SSIM = 0.89 ± 0.01), and were considerably different from the unsaturated dynamic image (SSIM = 0.58 ± 0.03). Conclusion The selection of the 3.5 ppm dynamic image as the reference image generated the highest uniformity index for APT imaging though other saturated images were equally suited as reference images.J. Magn. Reson. Imaging 2015.
    Print ISSN: 1053-1807
    Electronic ISSN: 1522-2586
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 3
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    Quantitative determination of Eliashberg function and evidence of strong electron coupling with multiple phonon modes in heavily overdoped (Bi,Pb)_{2}Sr_{2}CuO_{6+δ} (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-05-21
    Description: Author(s): Lin Zhao, Jing Wang, Junren Shi, Wentao Zhang, Haiyun Liu, Jianqiao Meng, Guodong Liu, Xiaoli Dong, Jun Zhang, Wei Lu, Guiling Wang, Yong Zhu, Xiaoyang Wang, Qinjun Peng, Zhimin Wang, Shenjin Zhang, Feng Yang, Chuangtian Chen, Zuyan Xu, and X. J. Zhou Superhigh resolution laser-based angle-resolved photoemission spectroscopy measurements have been carried out on a heavily overdoped (Bi,Pb) 2 Sr 2 CuO 6+ δ ( T c ~5 K) superconductor. Taking advantage of the high-precision data on the subtle change of the quasiparticle dispersion at different temperatures, ... [Phys. Rev. B 83, 184515] Published Fri May 20, 2011
    Keywords: Superfluidity and superconductivity
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 4
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    Atmosphere, Vol. 9, Pages 71: Analysis of the Influence of Rainfall Spatial Uncertainty on Hydrological Simulations Using the Bootstrap Method (2018)
    MDPI Publishing
    Details
    Publication Date: 2018-02-16
    Description: Atmosphere, Vol. 9, Pages 71: Analysis of the Influence of Rainfall Spatial Uncertainty on Hydrological Simulations Using the Bootstrap Method Atmosphere doi: 10.3390/atmos9020071 Authors: Ang Zhang Haiyun Shi Tiejian Li Xudong Fu Rainfall stations of a certain number and spatial distribution supply sampling records of rainfall processes in a river basin. Uncertainty may be introduced when the station records are spatially interpolated for the purpose of hydrological simulations. This study adopts a bootstrap method to quantitatively estimate the uncertainty of areal rainfall estimates and its effects on hydrological simulations. The observed rainfall records are first analyzed using clustering and correlation methods and possible average basin rainfall amounts are calculated with a bootstrap method using various combinations of rainfall station subsets. Then, the uncertainty of simulated runoff, which is propagated through a hydrological model from the spatial uncertainty of rainfall estimates, is analyzed with the bootstrapped rainfall inputs. By comparing the uncertainties of rainfall and runoff, the responses of the hydrological simulation to the rainfall spatial uncertainty are discussed. Analyses are primarily performed for three rainfall events in the upstream of the Qingjian River basin, a sub-basin of the middle Yellow River; moreover, one rainfall event in the Longxi River basin is selected for the analysis of the areal representation of rainfall stations. Using the Digital Yellow River Integrated Model, the results show that the uncertainty of rainfall estimates derived from rainfall station network has a direct influence on model simulation, which can be conducive to better understand of rainfall spatial characteristic. The proposed method can be a guide to quantify an approximate range of simulated error caused by the spatial uncertainty of rainfall input and the quantified relationship between rainfall input and simulation performance can provide useful information about rainfall station network management in river basins.
    Electronic ISSN: 2073-4433
    Topics: Geosciences
    Published by MDPI Publishing
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  • 5
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    Research on vehicle distribution model based on POT theory (2018)
    Institute of Physics (IOP)
    Details
    Publication Date: 2018-06-03
    Description: The vehicle overload phenomenon in expressway has become increasingly serious in China. Research on the extreme value of the vehicle load with its development trend is an urgent problem in the toll-by-weight mode. On the basis of statistical analysis of WIM data in Beijing-Zhuhai Expressway, by the extreme value theory and POT theory, a POT model had been developed. Vehicle weight distribution in the tail of the distribution function was obtained, which can predict the extreme value of vehicle load in any return period. Results showed that more heavy vehicles will appear in the future. It provided a useful reference for effective forecast of overweight vehicles.
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
    Published by Institute of Physics (IOP)
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