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  • 1
    Electronic Resource
    Electronic Resource
    Optical gain control model of the quantum-well laser diode (1991)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 5246-5253 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of various structure parameters such as graded potential, strain, quantum-well size, barrier heights, and temperature on the optical gain of single quantum-well lasers are studied for a potential solution to the problem of device optimization from the unified point of view with a rigorous model for gain. This study on the structure parameter dependence of the gain with the valence band mixing as well as intraband relaxation is new and presents a unified scheme for the optical gain control. Significant enhancement of gain in the graded quantum well as compared with that of the ordinary square quantum well is predicted. With the uniaxial stress, the TE mode gain is suppressed while the TM mode gain is enhanced due to the change of valence band structure. Calculated results show that the roles played by structure parameters such as well width, barrier heights, and temperature on the optical gain becomes of great importance for the device optimization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.350373
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Theoretical analysis of strained-layer InGaAs/GaAs quantum-well lasers with gain suppression and valence-band mixing (1992)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 60 (1992), S. 548-550 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Linear gain, gain suppression, and L-I characteristics of strained-layer InGaAs/GaAs quantum-well laser are studied theoretically, taking into account valence-band mixing effects with biaxial compressive strain. It is found that the biaxial compressive strain substantially alters subband structure by pushing the light-hold subband bands into higher-energy states. It also alters the optical gain of a quantum-well laser. In particular, the biaxially compressed strained-layer InGaAs/GaAs quantum well shows a pronounced preference for TE polarization over TM polarization and the higher optical gain than does a typical GaAs/AlGaAs quantum well. The L-I characteristics are obtained self-consistently from the rate equations for the carrier and the photon densities and the calculated L-I curve shows reasonable agreement with the experimental data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.106603
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Optical gain of CdZnSe/ZnSe quantum well lasers (1991)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 59 (1991), S. 2669-2671 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Polarization-dependent optical gain of recently demonstrated CdZnSe/ZnSe quantum well lasers is calculated for the first time. Our analysis is based on the multiband effective mass theory (k⋅p theory) and the density matrix formalism with intraband relaxation taken into account. It is shown theoretically that the TE mode gain is significantly larger than the TM mode gain for a wide range of carrier density. Comparison of the room-temperature TE mode gain of CdZnSe/ZnSe quantum well with that of GaAs/AlGaAs quantum well gives disappointing results for the II-VI semiconductor lasers. It is expected that the optical gain of the ZnSe-based semiconductor lasers would be substantially smaller than the optical gain of the GaAs-based semiconductor lasers for a same quantum well width and carrier density.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.105901
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  • 4
    Electronic Resource
    Electronic Resource
    Scribing and cutting a blue LED wafer using a Q-switched. Nd:YAG laser (2000)
    Springer
    Applied physics 70 (2000), S. 561-564 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 42.62; 85.60.J; 52.75.R
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Sapphire wafer is found to be scribed and cut freely by plasma from a metal surface on which a Q-switched Nd:YAG laser beam is focused through the wafer. The wafer is scribed enough to be cut using a Q-switched Nd:YAG laser with the average power of 5 W at atmospheric environment without a vacuum chamber. This method is successfully applied to split each device from a blue LED wafer including about 10000 blue LED devices grown on a sapphire wafer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390051080
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    Paper (German National Licenses)
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  • 5
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    Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L) (2014)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2014-02-21
    Description: Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L) Cell Death and Disease 5, e1063 (February 2014). doi:10.1038/cddis.2014.35 Authors: K-j Min, B R Seo, Y C Bae, Y H Yoo & T K Kwon
    Keywords: thioridazineTRAILAktMcl-1c-FLIPROS
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Nature Publishing Group (NPG)
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  • 6
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    Cafestol overcomes ABT-737 resistance in Mcl-1-overexpressed renal carcinoma Caki cells through downregulation of Mcl-1 expression and upregulation of Bim expression (2014)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2014-11-07
    Description: Cafestol overcomes ABT-737 resistance in Mcl-1-overexpressed renal carcinoma Caki cells through downregulation of Mcl-1 expression and upregulation of Bim expression Cell Death and Disease 5, e1514 (November 2014). doi:10.1038/cddis.2014.472 Authors: S M Woo, K-j Min, B R Seo, J-O Nam, K S Choi, Y H Yoo & T K Kwon
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Nature Publishing Group (NPG)
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  • 7
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    Identifying the potential long-term survivors among breast cancer patients with distant metastasis (2016)
    Oxford University Press
    Details
    Publication Date: 2016-04-26
    Description: Background We aimed to develop a prediction model to identify long-term survivors after developing distant metastasis from breast cancer. Patients and methods From the institution's database, we collected data of 547 patients who developed distant metastasis during their follow-ups. We developed a model that predicts the post-metastasis overall survival (PMOS) based on the clinicopathologic factors of the primary tumors and the characteristics of the distant metastasis. For validation, the survival data of 254 patients from four independent institutions were used. Results The median duration of the PMOS was 31.0 months. The characteristics of the initial primary tumor, such as tumor stage, hormone receptor status, and Ki-67 expression level, and the characteristics of the distant metastasis presentation including the duration of disease-free interval, the site of metastasis, and the presence of metastasis-related symptoms were independent prognostic factors determining the PMOS. The association between tumor stage and the PMOS was only seen in tumors with early relapses. The PMOS score, which was developed based on the above six factors, successfully identified patients with superior survival after metastasis. The median PMOS for patients with a PMOS score of 〈2 and for patients with a PMOS score of 〉5 were 71.0 and 12 months, respectively. The clinical significance of the PMOS score was further validated using independent multicenter datasets. Conclusions We have developed a novel prediction model that can classify breast cancer patients with distant metastasis according to their survival after metastasis. Our model can be a valuable tool to identify long-term survivors who can be potential candidates for more intensive multidisciplinary approaches. Furthermore, our model can provide a more reliable survival information for both physicians and patients during their informed decision-making process.
    Print ISSN: 0923-7534
    Electronic ISSN: 1569-8041
    Topics: Medicine
    Published by Oxford University Press
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