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  • 1
    Online Resource
    Online Resource
    Toronto :University of Toronto Press,
    Keywords: Electronic books.
    Description / Table of Contents: Biochemistry is a relatively new science in Canada. E. Gordon Young, an early specialist in the field who knew personally many of the prominent biochemists in this country, is a particularly appropriate writer for this first history of the development of the science in Canada. He deals with the origins and development of biochemistry.
    Type of Medium: Online Resource
    Pages: 1 online resource (147 pages)
    Edition: 1st ed.
    ISBN: 9781487575816
    Series Statement: Heritage Series
    Language: English
    Note: Cover -- PREFACE -- INTRODUCTION -- ORIGINS AND DEVELOPMENT AT THE UNIVERSITIES -- McGill -- Alberta -- Toronto -- Manitoba -- Western Ontario -- Dalhousie -- Montreal -- Laval -- Queen's -- Saskatchewan -- Ottawa -- British Columbia -- McMaster -- Summary and analysis -- Pathological chemistry -- Toronto -- Western Ontario -- McGill -- BIOCHEMISTRY IN AGRICULTURAL COLLEGES -- BIOCHEMISTRY IN INDUSTRY -- BIOCHEMISTRY IN GOVERNMENT LABORATORIES -- National Research Council -- Atomic Energy of Canada Ltd. -- Department of the Environment -- Fisheries Research Board -- Forest Products Laboratories -- Department of National Health and Welfare -- Food and Drug Laboratories -- Division of Nutrition -- Department of Agriculture -- Agricultural institutes -- Grain Research Laboratory -- Animal Research Institute -- Food Research Institute -- Chemistry and Biology Research Institute -- Plant Research Institute -- Agricultural Research Institute -- Other research institutes -- Provincial research laboratories -- BIOCHEMISTRY IN SPECIAL INSTITUTES -- McGill-Montreal General Hospital Research Institute -- Allan Memorial Institute of Psychiatry -- Montreal Neurological Institute -- The Banting Institute -- Banting and Best Department of Medical Research -- Charles H. Best Institute -- Hospital for Sick Children Research Institute, Toronto -- National Cancer Institute -- BIOCHEMISTRY IN CANADA IN PERSPECTIVE -- Endocrinology -- Neurochemistry -- Carbohydrate chemistry -- Phytochemistry -- BIOCHEMICAL SOCIETIES AND JOURNALS -- Societies -- Journals -- DISTINGUISHED EXPATRIATED BIOCHEMISTS -- FINANCIAL SUPPORT OF BIOCHEMICAL RESEARCH -- TECHNICAL PROGRESS -- REFERENCES -- APPENDIX: List of biochemists cited, with academic qualifications -- INDEX OF NAMES -- INDEX OF INSTITUTIONS.
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  • 2
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Marine algae -- Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (447 pages)
    Edition: 1st ed.
    ISBN: 9781483165523
    Language: English
    Note: Front Cover -- Seaweed Symposium -- Copyright Page -- Table of Contens -- INTERNATIONAL ADVISORY COMMITTEE -- FOREWORD -- LIST OF ACTIVE MEMBERS -- PART 1: SPECIAL LECTURES -- CHAPTER 1. SOME RECENT STUDIES ON THE POLYSACCHARIDES OF AGAROPHYTES -- ABSTRACT -- REFERENCES -- CHAPTER 2. LOCALIZATION AND STRUCTURE OF ALGINATE GELS -- ABSTRACT -- LOCALIZATION OF ALGINATE -- STRUCTURE OF ALGINATE GELS -- REFERENCES -- CHAPTER 3. THE PHYSIOLOGICAL ECOLOGY OF SOME NEW ZEALAND SEAWEEDS -- ABSTRACT -- INTRODUCTION -- DESICCATION -- PHOTOSYNTHESIS AND LIGHT INTENSITY DURING SUBMERGENCE -- PHOTOSYNTHESIS DURING RE-IMMERSION -- PHOTOSYNTHESIS IN RELATION TO TEMPERATURE AND OTHER FACTORS -- RESPIRATION -- SUBSIDIARY DATA -- SUMMARY -- CONCLUSION -- REFERENCES -- CHAPTER 4. THE SEAWEED INDUSTRY OF THE FUTURE -- ABSTRACT -- ORIENTED LONG-TERM RESEARCH -- APPLIED RESEARCH AND DEVELOPMENT -- PART 2: ORIGINAL COMMUNICATIONS I. BIOLOGY -- CHAPTER 5. IN SITU STUDIES OF SPORE PRODUCTION AND DISPERSAL IN THE GIANT KELP, MACROCYSTIS -- ABSTRACT -- INTRODUCTION -- METHODS -- RESULTS -- DISPERSAL -- DISCUSSION -- SUMMARY -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 6. THE LIFE CYCLE OF ACROCHAETIUM LIAGORAE BӦRG -- ABSTRACT -- REFERENCES -- CHAPTER 7. DISTRIBUTION OF MARINE ALGAE IN THE BAY OF FUNDY, NEW BRUNSWICK, CANADA -- ABSTRACT -- INTRODUCTION -- DESCRIPTION OF THE STATIONS -- ANALYSES OF THE FLORAS OF ST. ANDREWS AND LEPREAU -- VERTICAL DISTRIBUTION-WEST ATLANTIC -- ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 8. EFFECT OF TANNINS EXCRETED FROM PHAEOPHYTA ON PLANKTONIC ANIMAL SURVIVAL IN TIDE POOLS -- REFERENCE -- CHAPTER 9. JUVENILE STAGES IN THE GENUS PORPHYRA -- ABSTRACT -- REFERENCES -- CHAPTER 10. PRELIMINARY REPORT ON THE MARINE VEGETATION OF THE ANTARCTIC PENINSULA -- ABSTRACT -- INTRODUCTION -- THE INFRALITTORAL BELT -- THE SUPRALITTORAL AND LITTORAL BELTS. , ACKNOWLEDGMENTS -- REFERENCES -- CHAPTER 11. WINTER OBSERVATIONS ON SPECIES OF PORPHYRA FROM HALIFAX COUNTY, NOVA SCOTIA -- ABSTRACT -- INTRODUCTION -- OBSERVATIONS -- DISCUSSION -- REFERENCES -- CHAPTER 12. ALGUES DE LA CÔTE ATLANTIQUE PORTUGUAISE -- CHAPTER 13. OBSERVATIONS ON THE MARINE ALGAL FLORA OF BARBADOS -- CHAPTER 14. A TWO-STAGE SAMPLING METHOD OF ESTIMATING SEAWEED QUANTITIES -- ABSTRACT -- INTRODUCTION -- APPLICATION -- REFERENCES -- CHAPTER 15. THE PLACE OF SEAWEEDS IN A GENERAL EVOLUTIONARY THEORY FOR PLANTS -- CHAPTER 16. ALGAL COLONIZATION AFTER REMOVAL OF ECHINUS -- CHAPTER 17. ECOLOGICAL RELATIONSHIPS BETWEEN GIANT KELP AND SEA URCHINS IN SOUTHERN CALIFORNIA -- ABSTRACT -- INTRODUCTION -- GRAZING -- CAUSES OF ECOLOGICAL IMBALANCE -- CONTROL OF URCHINS -- SUMMARY -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 18. ON THE OCCURRENCE OF UNILOCULAR SPORANGIA IN THE LIFE-HISTORY OF SCYTOSIPHON LOMENTARIA (LYNGB.) J.AG -- CHAPTER 19. CONNECTIVE TISSUE STIMULATION IN GUINEA PIGS BY POLYSACCHARIDES DERIVED FROM MARINE ALGAE -- ABSTRACT -- INTRODUCTION -- EXPERIMENTAL -- RESULTS AND DISCUSSION -- SUMMARY -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 20. CORRELATED LIGHT AND ELECTRON MICROSCOPE STUDIES OF THE CELL WALLS OF FUCUS -- CHAPTER 21. SUBLITTORAL SURVEYING FOR COMMERCIAL SEAWEEDS IN NORTHUMBERLAND STRAIT -- ABSTRACT -- ECOLOGICAL CONDITION -- DETAILS OF SUBSTRATUM AND COVER - CAPE JOHN TO CARIBOU POINT -- REFERENCES -- CHAPTER 22. THE OCCURRENCE OF CHITAN, A β-(1β → 4)-LINKED 2-ACETAMIDO-2-DEOXY D-GLUCAN, IN DIATOMS -- CHAPTER 23. APICAL DOMINANCE IN FUCUS VESICULOSUS -- CHAPTER 24. DEVELOPMENT OF ZOOSPORES IN RALFSIA-LIKE THALLUS, WITH SPECIAL REFERENCE TO THE LIFE CYCLE OF THE SCYTOSIPHONALES -- CHAPTER 25. THE GAMETOPHYTE OF PADINA IN THE MEDITERRANEAN -- ABSTRACT -- NTRODUCTION -- MATERIALS AND METHODS -- OBSERVATIONS. , DISCUSSIONS -- SUMMARY -- REFERENCES -- CHAPTER 26. PERSISTENT, VERTICAL-MIGRATION RHYTHMS IN BENTHIC MICROFLORA. V. THE EFFECT OF ARTIFICIALLY IMPOSED LIGHT AND DARK CYCLES -- ABSTRACT -- INTRODUCTION -- METHODS -- RESULTS -- DISCUSSION -- REFERENCES -- CHAPTER 27. ON THE SPECIES AND DISTRIBUTION OF GELIDIUM IN JAPAN -- CHAPTER 28. ANTIFOULING IN SARGASSUM NATANS: RE-RECOGNITION OF TANNIN ACTIVITY -- REFERENCES -- CHAPTER 29. VARIATION IN THE GENUS POLYSIPHONIA GREVILLE -- ABSTRACT -- INTRODUCTION -- METHODS -- OBSERVATIONS -- DISCUSSION -- SUMMARY -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 30. THE OCCURRENCE OF BENTHIC MARINE ALGAE UNDER SHORE FAST-ICE IN THE WESTERN ROSS SEA, ANTARCTICA -- ABSTRACT -- SURVEY OF PREVIOUS WORK -- PRESENT INVESTIGATIONS -- LOCALITIES AND HABITATS -- MARINE ALGAL ZONATION -- LIGHT AND THE VERTICAL DISTRIBUTION OF ROSS SEA ALGAE -- SUMMARY -- REFERENCES -- PART 3: ORIGINAL COMMUNICATIONS II. CHEMISTRY -- CHAPTER 31. DIMETHYL-β-PROPIOTHETIN: DETERMINATION BY REACTOR GAS-LIQUID CHROMATOGRAPHY, OCCURRENCE IN ALGAE, AND IMPLICATIONS IN FISHERIES -- ABSTRACT -- INTRODUCTION -- EXPERIMENTAL PROCEDURES -- EXPERIMENTAL RESULTS -- DISCUSSION -- REFERENCES -- CHAPTER 32. THE REPEATING STRUCTURE OF SOME POLYSACCHARIDE SULPHATES FROM RED SEAWEEDS -- ABSTRACT -- INTRODUCTION AND DISCUSSION -- EXPERIMENTAL -- REFERENCES -- CHAPTER 33. THE EVALUATION OF SOME RED MARINE ALGAE AS A SOURCE OF CARRAGEENAN -- CHAPTER 34. ASPECTS OF RHODOPHYCEAN PHOTOSYNTHESIS -- CHAPTER 35. THE FINE STRUCTURE OF SOLUBLE LAMINARIN -- ABSTRACT -- THE BIOSYNTHESIS OF β-l,3-GLUCANS -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 36. STRUCTURAL STUDIES ON THE WATER-SOLUBLE POLYSACCHARIDE FROM THE GREEN SEAWEED ULVA LACTUCA PART IV. SMITH DEGRADATION -- ABSTRACT -- EXPERIMENTAL -- REFERENCES. , CHAPTER 37. A STUDY ON THE CONSTITUTION OF ALGINIC ACID BY PARTIAL ACID HYDROLYSIS -- ABSTRACT -- REFERENCES -- CHAPTER 38. A NOVEL BROMINATED PHENOLIC DERIVATIVE FROM POLYSIPHONIA LANOSA -- CHAPTER 39. TOCOPHEROL DETERMINATION IN SEAWEEDS -- ABSTRACT -- INTRODUCTION -- TOCOPHEROL DISTRIBUTION IN SEAWEEDS -- QUANTITATIVE DETERMINATION OF TOCOPHEROLS IN SEAWEEDS -- REFERENCES -- CHAPTER 40. PREPARATION AND STRUCTURAL INVESTIGATION OF ASCOPHYLLAN -- ABSTRACT -- REFERENCES -- CHAPTER 41. PHYSICO-CHEMICAL STUDIES ON CHITAN (PURE CRYSTALLINE β-(1 β → 4)-LINKED 2-ACETAMIDO-2-DEOXY-D-GLUCAN) -- CHAPTER 42. STUDIES ON THE SOLUBILITY OF ALGINIC ACID FROM ASCOPHYLLUM NODOSUM AT LOW pH -- ABSTRACT -- REFERENCES -- CHAPTER 43. THE LOCATION OF THE SULPHATE HALF-ESTER GROUPS IN FURCELLARAN AND ϰ-CARRAGEENAN -- ABSTRACT -- INTRODUCTION -- MATERIALS AND METHODS -- RESULTS AND DISCUSSION -- REFERENCES -- CHAPTER 44. AGAROSE AND AGAROPECTIN IN GELIDIUM AND GRACILARIA AGAR -- ABSTRACT -- EXPERIMENTAL -- SUMMARY -- REFERENCES -- CHAPTER 45. POLYSACCHARIDES FROM CORALLINA OFFICINALIS -- ABSTRACT -- REFERENCES -- CHAPTER 46. THE ENZYMIC HYDROLYSIS OF ϰ-CARRAGEENAN WITH ϰ-CARRAGEENASE FROM PSEUDOMONAS CARRAGEENOVORA -- ABSTRACT -- INTRODUCTION -- EXPERIMENTAL -- CONCLUSIONS -- REFERENCES -- CHAPTER 47. THE PURIFICATION AND PROPERTIES OF AN AGARASE FROM A MARINE BACTERIUM, PSEUDOMONAS ATLANTICA -- ABSTRACT -- REFERENCES -- CHAPTER 48. THE CHEMICAL NATURE OF THE INSOLUBLE RESIDUE AFTER SEVERE EXTRACTION IN SOME RHODOPHYCEAE AND PHAEOPHYCEAE -- ABSTRACT -- INTRODUCTION -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- ACKNOWLEDGEMENTS -- REFERENCES -- PART 4: ORIGINAL COMMUNICATIONS III. APPLICATIONS -- CHAPTER 49. SOME PROPERTIES OF SEAWEED MANURES -- ABSTRACT -- SEAWEED AND SEED GERMINATION -- SEAWEED AND FROST RESISTANCE -- EFFECT OF SEAWEED ON THE UPTAKE OF NUTRIENTS. , SEAWEED AND FUNGAL DISEASES -- SEAWEED AND INSECT PESTS -- CONCLUSIONS -- REFERENCES -- CHAPTER 50. GROWTH OF HIGHER PLANTS IN RESPONSE TO FEEDING WITH SEAWEED EXTRACTS -- ABSTRACT -- EXPERIMENTAL -- RESULTS -- DISCUSSION -- REFERENCES -- CHAPTER 51. AN EXPERIMENTAL CONTRIBUTION TO THE CLINICAL USE OF AN ALGAL PHYTOCOLLOID (ALGASOL T331) IN ONCOLOGY -- CHAPTER 52. AN EXPERIMENTAL CONTRIBUTION TO THE CLINICAL USE OF AN ALGAL PHYTOCOLLOID (ALGASOL T331) IN ONCOLOGY -- CHAPTER 53. SEAWEEDS AS RADIOACTIVITY INDICATORS OF MARINE ENVIRONMENT -- ABSTRACT -- MATERIALS AND METHODS -- DISCUSSION -- CHAPTER 54. A REPORT ON ALGINIC ACID AS A TABLET DISINTEGRANT -- CHAPTER 55. ABOUT THE MILK REACTIVITY OF SEVERAL RED SEAWEED EXTRACTS -- CHAPTER 56. THE USE OF GELLED ALGINATES FOR CONTROLLING THE FLOW OF WATER IN POROUS GROUND -- ABSTRACT -- INTRODUCTION -- EXPERIMENTAL -- DISCUSSION -- SUMMARY -- REFERENCES -- CHAPTER 57. SEAWEED MEAL AS A SOURCE OF MINERALS AND VITAMINS IN RATIONS FOR DAIRY COWS AND BACON PIGS -- ABSTRACT -- INTRODUCTION -- SUMMARY AND CONCLUSIONS -- REFERENCES -- CHAPTER 58. SUPPRESSION OF INTESTINAL ABSORPTION OF RADIOSTRONTIUM BY SUBSTANCES OCCURRING IN PHAEOPHYCEAE -- ABSTRACT -- GENERAL CONSIDERATIONS -- USE OF ALGINATE TO SUPPRESS ABSORPTION OF RADIOSTRONTIUM -- STRONTIUM89 ABSORPTION IN THE PRESENCE OF SODIUM ALGINATE -- APPLICABILITY IN HUMAN SUBJECTS -- DISCUSSION -- REFERENCES -- CHAPTER 59. THE EFFECT OF HYDROLYSED SEAWEED ON CERTAIN PLANT PESTS AND DISEASES -- ABSTRACT -- INTRODUCTION -- EXPERIMENTA -- DISCUSSION -- REFERENCES -- AUTHOR INDEX -- SUBJECT INDEX.
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  • 3
    Keywords: Konferenzschrift ; Meeresalgen
    Type of Medium: Book
    Pages: XVIII, 424 S , graph. Darst., Kt
    DDC: 589.3
    Language: English
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  • 4
    Publication Date: 2020-10-19
    Description: Nitrogen is the main constituent of the Earth's atmosphere, but its provenance in the Earth's mantle remains uncertain. The relative contribution of primordial nitrogen inherited during the Earth's accretion versus that subducted from the Earth's surface is unclear1-6. Here we show that the mantle may have retained remnants of such primordial nitrogen. We use the rare 15N15N isotopologue of N2 as a new tracer of air contamination in volcanic gas effusions. By constraining air contamination in gases from Iceland, Eifel (Germany) and Yellowstone (USA), we derive estimates of mantle δ15N (the fractional difference in 15N/14N from air), N2/36Ar and N2/3He. Our results show that negative δ15N values observed in gases, previously regarded as indicating a mantle origin for nitrogen7-10, in fact represent dominantly air-derived N2 that experienced 15N/14N fractionation in hydrothermal systems. Using two-component mixing models to correct for this effect, the 15N15N data allow extrapolations that characterize mantle endmember δ15N, N2/36Ar and N2/3He values. We show that the Eifel region has slightly increased δ15N and N2/36Ar values relative to estimates for the convective mantle provided by mid-ocean-ridge basalts11, consistent with subducted nitrogen being added to the mantle source. In contrast, we find that whereas the Yellowstone plume has δ15N values substantially greater than that of the convective mantle, resembling surface components12-15, its N2/36Ar and N2/3He ratios are indistinguishable from those of the convective mantle. This observation raises the possibility that the plume hosts a primordial component. We provide a test of the subduction hypothesis with a two-box model, describing the evolution of mantle and surface nitrogen through geological time. We show that the effect of subduction on the deep nitrogen cycle may be less important than has been suggested by previous investigations. We propose instead that high mid-ocean-ridge basalt and plume δ15N values may both be dominantly primordial features.
    Description: Published
    Description: 367–371
    Description: 3V. Proprietà chimico-fisiche dei magmi e dei prodotti vulcanici
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
    Publication Date: 2021-06-21
    Description: We report measurements of resolved 12CH2D2 and 13CH3D at natural abundances in a variety of methane gases produced naturally and in the laboratory. The ability to resolve 12CH2D2 from 13CH3D provides unprecedented insights into the origin and evolution of CH4. The results identify conditions under which either isotopic bond order disequilibrium or equilibrium are expected. Where equilibrium obtains, concordant D12CH2D2 and D13CH3D temperatures can be used reliably for thermometry. We find that concordant temperatures do not always match previous hypotheses based on indirect estimates of temperature of formation nor temperatures derived from CH4/H2 D/H exchange, underscoring the importance of reliable thermometry based on the CH4 molecules themselves. Where D12CH2D2 and D13CH3D values are inconsistent with thermodynamic equilibrium, temperatures of formation derived from these species are spurious. In such situations, while formation temperatures are unavailable, disequilibrium isotopologue ratios nonetheless provide novel information about the formation mechanism of the gas and the presence or absence of multiple sources or sinks. In particular, disequilibrium isotopologue ratios may provide the means for differentiating between methane produced by abiotic synthesis vs. biological processes. Deficits in 12CH2D2 compared with equilibrium values in CH4 gas made by surface-catalyzed abiotic reactions are so large as to point towards a quantum tunneling origin. Tunneling also accounts for the more moderate depletions in 13CH3D that accompany the low 12CH2D2 abundances produced by abiotic reactions. The tunneling signature may prove to be an important tracer of abiotic methane formation, especially where it is preserved by dissolution of gas in cool hydrothermal systems (e.g., Mars). Isotopologue signatures of abiotic methane production can be erased by infiltration of microbial communities, and D12CH2D2 values are a key tracer of microbial recycling.
    Description: Published
    Description: 235-264
    Description: 6A. Geochimica per l'ambiente
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of medicinal chemistry 13 (1970), S. 1253-1253 
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 3593-3599 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The diffusion of iron and zinc in InP is studied with secondary-ion mass spectrometry (SIMS). Intentionally doped metalorganic-vapor-phase-epitaxy- (MOVPE-) grown layers as well as ion-implanted samples were investigated. In addition, resistivity measurements were performed on MOVPE-grown, iron-doped InP layers. The diffusion behavior of iron is strongly influenced by the presence of zinc and vice versa. In adjacent regions of iron and zinc-doped layers of InP there is a dramatic interdiffusion of both dopants. The interdiffusion process can be described with a kick-out mechanism in which iron interstitials kick out substitutional zinc. The diffusion of the iron interstitials is an extremely fast transport process in InP, but the concentration of iron interstitials remains below 5×1014 at cm−3. Due to this fast transport, the interdiffusion process proceeds even through barrier layers of (undoped) InP, while in the barrier layer itself the iron concentration remains below the SIMS detection limit (〈5×1014 at cm−3). A sulphur-doped, n-type layer of InP stops the diffusion of iron. The semi-insulating properties of iron-doped layers of InP are affected by the interdiffusion process of iron and zinc. Since sulphur-doped InP inhibits the interdiffusion, such a layer can be applied as a barrier layer to separate zinc-doped and iron-doped regions in InP and thus preserve the semi-insulating character of the iron-doped InP.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 63 (1994), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Aromatic l-amino acid decarboxylase (AAAD) is required for the synthesis of catecholamines, serotonin, and the trace amines. We found that the protein kinase C activator phorbol 12-myristate 13-acetate administered intracerebroventricularly transiently increased AAAD activity by 30–50% over control values within ∼30 min in the striatum and midbrain of the mouse. The enzyme increase was manifested as an apparent increase of Vmax with little change of Km for either l-3,4-dihydroxyphenylalanine or pyridoxal phosphate. Chelerythrine, a protein kinase C inhibitor, prevented the phorbol ester-induced increase of AAAD. Moreover, okadaic acid, a serine/threonine-selective protein phosphatase 1 and 2A inhibitor, also increased AAAD activity in the mouse striatum and midbrain. Taken together, these observations suggest that protein kinase C-mediated pathways modulate AAAD activity in vivo.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 60 (1993), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Aromatic L-amino acid decarboxylase (AAAD) activity of mouse striatum and midbrain increased after an intracerebro-ventricular injection of either forskolin or 8-bromo-cyclic AMP. The increase was transient, peaking between 15 and 30 min and returning to baseline by ˜90 min. The increase of AAAD activity after forskolin was not affected by pretreatment with cycloheximide. Kinetic studies indicated an apparent increase of Vmax with little change of the Km for L-DOPA or pyridoxal 5′-phosphate. We conclude that AAAD activity of striatum and midbrain can be modulated by a cyclic AMP-dependent process.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 137 (1997), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Compositae dermatitis is rare in childhood, with few cases documented in the literature. We report a 7-year-old boy who presented with a dermatitis mainly affecting his dominant hand. Patch testing revealed contact sensitivity to sesquiterpene lactone (SL) mix, and subsequent testing with Compositae oleoresins showed sensitivity to daisy, dandelion and chrysanthemum. The dermatitis improved on avoidance of handling plants. We have not documented any other cases of Compositae sensitivity in 187 other children, aged under 16 years, who have undergone patch testing with SL mix between 1992 and 1996 in our department. This case illustrates that Compositae sensitivity may present with a localized dermatitis and that, although uncommon, sensitization may occur in early childhood.
    Type of Medium: Electronic Resource
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