Note: Front Cover -- Intercellular Communication through Gap Junctions -- Copyright Page -- Preface -- Table of Contents -- Part I: Connexin -- CHAPTER 1. THE CONNEXIN FAMILY TREE -- INTRODUCTION -- SEQUENCE COMPARISONS -- THE TREE(S) -- SUMMARY -- ACKNOWLEDGEMENTS -- REFERENCES -- Chapter 2. Exogenous Expression of Connexins for Physiological Characterization of Channel Properties: Comparison of Methods and Results -- 1. CLONING OF CONNEXIN DNAs -- 2. EXOGENOUS EXPRESSION OFCONNEXINS -- 3. USEFULNESS OF EXOGENOUS EXPRESSION -- 4. CONCLUSIONS -- REFERENCES -- Part II: Development and Gap Junctions -- Chapter 3. Expression pattern of different connexins in comparison with communication compartments during early mouse development -- 1. Introduction -- 2. Mouse blastocysts express Cx31 protein in both the inner cell mass and the trophectoderm -- 3. Cx31 and Cx43 expression is strictly compartmentalized in the gastrulating mouse embryo -- 4. Compartmentalization of Cx31 and Cx43 expression may establish communication compartments -- 5. Conclusions -- Acknowledgements -- References -- Chapter 4. Junctional communication and notochord differentiation -- REFERENCES -- Chapter 5. Increased Junctional Communication and Forced Expression of Connexin43 Retards Cell Growth and Enhances Myogenic Differentiation in Rhabdomyosarcoma Cells -- INTRODUCTION -- MATERIALS AND METHODS -- RESULTS AND DISCUSSION -- REFERENCES -- Chapter 6. Gap junction in the apoptosis: TEM observation of membrana-granulosa cells of mouse ovarian follicle -- INTRODUCTION -- STRUCTURAL FEATURES OF APOPTOTIC CELL -- GJ BETWEEN NORMAL-APPEARING CELL AND APOPTOTIC CELL -- CYTOPLASMIC FILAMENTS ACT IN INTERNALIZATION OF GJ -- REFERENCES -- Chapter 7. Influence of steroid hormones on connexin expression in rat endometrium -- INTRODUCTION -- METHODS -- RESULTS -- CONCLUSIONS -- REFERENCES. , Chapter 8. Expression patterns of different connexin genes associated with trophoblast invasion and differentiation -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. CONCLUSIONS -- REFERENCES -- CHAPTER 9. ENERGY COUPLING OF ADJACENT CELLS AS A UNIVERSAL FUNCTION OF CELL-TO-CELL PERMEABLE JUNCTIONS -- 1.INTRODUCTION. -- 2. EXPERIMENTAL APPROACHES. -- 3. CONCLUSION. -- REFERENCES -- Part III: Gastric Mucosa and Gap Junctions -- CHAPTER 10. MULTIPLE CONNEXIN MESSENGER RNAS EXPRESSED BY HUMAN GASTROINTESTINAL SMOOTH MUSCLES AND MUCOSA -- INTRODUCTION -- METHOD AND MATERIALS -- RESULTS -- DISCUSSION -- REFERENCES -- Chapter 11. Role of gap junctions in gastric mucosal protection in rats -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- References -- Chapter 12. Intercellular Communication Regulation at the Gap Junction Using Cultured Rabbit Gastric Epithelial Cells -- Introduction -- Materials and Methods -- Results -- Discussion -- References -- Chapter 13. Intracellular calcium downregulates gap-junctional intercellular communication in cultured rabbit gastric epithelial cells -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES -- Part IV: Carcinogenesis and Gap Junctions -- Chapter 14. Aberrant control of connexin expression and functions in multistage rat and human hepatocarcinogenesis -- 1. INTRODUCTION -- 2. CHANGES IN GJIC (MEASURED BY DYE TRANSFER ASSAY) IN RAT AND HUMAN TUMORS -- 3. CONNEXIN GENE AND PROTEIN EXPRESSION -- 4. MUTATIONS OF THE CONNEXIN 32 GENE -- 5. CONCLUSION AND DISCUSSION -- ACKNOWLEDGEMENT -- REFERENCES -- Chapter 15. Is the intracellular localization of connexin 43 a possible mechanism for the TPA-induced inhibition of rat liver epithelial cells junctional coupling? -- 1. Introduction -- 2. Methods -- 3. Results and Discussion. , 4. Conclusions -- References -- Chapter 16. Role of cell adhesion molecules in endothelial cell/tumor cell communication and tumor cell extravasation -- 1. Introduction -- 2. Gap junctions in cancer -- 3. Adhesion and gap junctions -- 4. Conclusions -- References -- Chapter 17. Ex-vivo dye transfer assay as an approach to study gap junctional intercellular communication disorders in hepatocarcinogenesis -- 1. INTRODUCTION -- 2. DYE TRANSFER ASSAY IN FRESH LIVER SLICES -- 3. RESULTS -- Acknowledgement -- References -- Chapter 18. Alteration of connexin 32 content in acute and chronic liver injury induced by carbon tetrachloride in rats -- 1. INTRODUCTION -- 2. METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES -- Chapter 19. Expression of multiple connexins is differentially modulated during multistage hepatocarcinogenesis -- 1. INTRODUCTION -- 2. RAT HEPATOCARCINOGENESIS [2] -- 3. MOUSE HEPATOCARCINOGENESIS -- REFERENCES -- Chapter 20. Decreased connexin 32 expression is associated with cellular proliferation and progression of hepatocarcinogenesis in the rat -- 1. Introduction -- 2. Materials and Methods -- 3. Results -- 4. Discussion and Conclusions -- 5. Acknowledgments -- References -- Chapter 21. Characterization of isolated guinea pig liver gap junctions -- Introduction -- Materials and Methods -- Results -- Discussion -- Acknowledgement -- References -- Chapter 22. Utility of an anti-Connexin 32 monoclonal antibody (HAM8) for analyzing gap junction formation and expression -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 23. The Effect of 3,4,5,3',4'-Pentachlorobiphenyl and 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Gap Junction Intercellular Communication in vitro and in vivo -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION. , 5. ACKNOWLEDGEMENTS -- 6. REFERENCES -- Chapter 24. Gap junctional intercellular communication : a European collaborative study -- INTRODUCTION -- RESEARCH PROGRAMME -- METHODS -- RESULTS -- CONCLUSION -- REFERENCES -- Chapter 25. Connexin 43 -- A possible new marker protein for preneoplastic and neoplastic lesions in hepatocarcinogenesis of rats -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULT -- 4. DISCUSSION -- REFERENCES -- CHAPTER 26. MAINTENANCE OF THE DIFFERENTIATED STATE OF HEPATOCYTES OF ADULT RATS DOES NOT APPEAR TO REQUIRE ELECTRICAL COUPLING WITH THE BILIARY EPITHELIAL CELLS GROWN IN CO-CULTURE WITH THEM. -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- ACKNOWLEDGEMENTS -- REFERENCES -- Chapter 27. Cell communication and morphological transformation in Syrian hamster embryo cells -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS AND DISCUSSION -- REFERENCES -- Chapter 28. Growth inhibition by expression of connexin 26 in HeLa cells -- 1. INTRODUCTION -- 2. CHARACTERISTICS OF THE TRANSFECTED HeLa CELLS -- 3. DISCUSSION AND CONCLUSIONS -- REFERENCES -- Chapter 29. Deducing connexin stoichiometry in isolated liver gap junction plaques from images obtained with scanning transmission electron microscopy -- 1. INTRODUCTION -- 2. PREPARATION OF SPECIMENS FOR ELECTRON MICROSCOPY -- 3. DIGITAL IMAGE PROCESSING -- 4. ANALYSIS OF THE STEM IMAGES -- ACKNOWLEDGMENTS -- REFERENCES -- Part V: Cardiac Muscles and Gap Junctions -- Chapter 30. Gap junction formation and regulation in cultured adult rat and guinea pig cardiac muscle cells -- 1. INTRODUCTION -- 2. MATERIALS and METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES. , Chapter 31. Involvement of Connexin43 Localization and Gap Junctional Intercellular Communication in the Establishment of a Synchronized Contraction of Cultured Neonatal Rat Cardiac Myocytes -- 1. INTRODUCTION -- 2. EXPERIMENTAL PROCEDURE -- 3. RESULT -- 4. DISCUSSION -- REFERENCES -- Chapter 32. Depressing effect of polyclonal antibodies directed against a carboxy-terminus domain of connexin43 on cell-to-cell dye-transfer in cultured heart myocytes -- 1. INTRODUCTION -- 2. MATERIAL AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES -- Chapter 33. Interruption of cell-to-cell communication triggered in cardiac cells by a synthetic diacylglycerol -- 1. INTRODUCTION -- 2. MATERIALS AND METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES -- Chapter 34. Intercellular Metabolic Coupling of Glutathione Between Mouse and Quail Cardiac Myocytes and Its Protective Role Against Oxidative Stress -- 1. ABSTRACT -- 2. INTRODUCTION -- 3. METHODS -- 4. RESULTS AND DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 35. Studies of connexin 43 and cell-to-cell coupling in cultured human myometrial cells -- INTRODUCTION -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- REFERENCES -- Chapter 36. Expression and distribution of connexin 40 in mammal heart -- 1. INTRODUCTION -- 2. RESULTS AND DISCUSSION -- REFERENCES -- CHAPTER 37. MULTIPLE CONNEXINS AND ASYMMETRIC CURRENTS IN EMBRYONIC CARDIAC GAP JUNCTIONS -- REFERENCES -- Chapter 38. The fluidity of membranous cholesterol-rich domains is of importance to cardiac gap junctional conductance. -- 1. INTRODUCTION -- 2. RESULTS AND DISCUSSION -- 3. ACKNOWLEDGEMENTS -- 4. REFERENCES -- Chapter 39. Patch Clamp of Gap Junction Containing Membranes in Guinea-Pig Ventricular Myocytes -- 1. INTRODUCTION -- 2. METHODS -- 3. RESULTS -- 4. DISCUSSION -- REFERENCES:. , Chapter 40. Presence and physiological significance of gap junctions in vascular smooth muscle.

Note: Keio University Symposia for Life Science and Medicine 5 -- Cell Therapy -- Copyright -- Foreword -- Preface -- Contents -- List of Contributors -- Opening Remarks* -- Part 1 Immunotherapy for Malignant Diseases -- Breaking Immunological Tolerance to Tumor Cells as a Novel Immunotherapy for Cancer -- SARTI Gene Encoding Squamous Cell Carcinoma Antigen Recognized by Cytotoxic T Lymphocytes -- Adoptive Immunotherapy of Human Diseases with Antigen-Specific T-Cell Clones -- Adoptive Transfer of Polyclonal, EBV-Specific Cytotoxic T-Cell Lines for the Prevention and Treatment of EBV-Associated Malignancies -- Processing of Antigens by Dendritic Cells: Nature's Adjuvant -- Immunotherapy of Melanoma Using Dendritic Cells -- Immunotherapy of Melanoma Using T-Cell-Defined Antigens -- Part 2 Hematopoietic Stem Cells Biology and Clinical Application -- Isolation and Characterization of CD34- Low/Negative Mouse Hematopoietic Stem Cells -- Ex Vivo Expansion of Human Hematopoietic Stem Cells -- Notch in Hematopoiesis: Cell Fate Decisions and Self-Renewal of Progenitors -- Molecular Genetics of Acute Promyelocytic Leukemia: A Rationale for "Transcription Therapy" for Cancer -- A Novel Acute Promyelocytic Leukemia Model: From Cell to Murine System -- Phase 1 Trial of Retroviral-Mediated Transfer of the Human MDR-1 in Patients Undergoing High-Dose Chemotherapy and Autologous Stem Cell Transplantation -- Basic Studies Toward Hematopoietic Stem Cell Gene Therapy -- Ex Vivo Expansion of Hematopoietic Cells -- Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy -- Ex Vivo Expansion of Human Cord Blood Stem Cells and Genetic Manipulation -- Part 3 International Collaboration in Hematopoietic Stem Cell Transplantation -- Unrelated Donor Stem Cell Transplantation: A Registry Perspective -- European Bone Marrow Donor Registries: Collaboration and Individualism. , Asian Bone Marrow Donor Registries: Their Roles in International Cooperation -- Cord Blood Stem Cell Transplantation: Banking and Clinical Results -- Key Word Index.

Note: "Translation into English by Dr. Peter Muckley from Equidad, Derecho y Justicia Madrid, Editorial Universitaria Ramon Areces, 2005 , Includes bibliographical references (p. [279]-329) and index