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  • 1
    Electronic Resource
    Electronic Resource
    Intrapartum fetal cerebral near infrared spectroscopy: apparent change in oxygenation demonstrated in a nonviable fetus (1996)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 103 (1996), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1996.tb09572.x
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of maternal posture on fetal cerebral oxygenation during labour (1995)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To measure the effect of changes in maternal posture on fetal cerebral oxygenation during normal labour.Design A prospective study comparing changes in the fetal cerebral concentrations of oxy-haemoglobin, deoxyhaemoglobin and cerebral blood volume, measured by near infrared spectroscopy, in women with effective epidural analgesia when moved from the left lateral to the supine position during labour.Setting A London teaching hospital obstetric unit.Subjects Fourteen women during uncomplicated labour at term.Results When compared with the left lateral position, the supine position was associated with a significant decrease in the mean concentration of fetal cerebral oxyhaemoglobin of 1.12 (SD 1.0, 95% CI 0.49 to 1.75) μmol. 100 g−1(P 〈 0.01) without any significant change in the mean concentration of deoxyhaemoglobin and cerebral blood volume. These changes were associated with a significant decrease in the mean cerebral oxygen saturation of 8.3 (SD 8.8, 95% CI 1.5 to 15.1)% (P 〈 0.05, n= 9).Conclusion Changes in maternal posture during labour, in women with effective epidural analgesia, are associated with a significant decrease in fetal cerebral oxygenation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1995.tb09019.x
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  • 3
    Electronic Resource
    Electronic Resource
    Late fetal heart decelerations and changes in cerebral oxygenation during the first stage of labour (1995)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To test the hypothesis that late fetal heart rate decelerations are associated with a decrease in cerebral oxygenation.Design Changes in fetal cerebral concentrations of oxyhaemoglobin and deoxyhaemoglobin were measured by near infrared spectroscopy, before, during and after contractions with late fetal heart rate decelerations and compared with changes during contractions with no alteration of heart rate.Setting Teaching hospital obstetric unit.Subjects Ten women in labour at term.Results The changes in fetal cerebral oxyhaemoglobin and deoxyhaemoglobin concentrations that occurred during contractions were quantitatively similar, irrespective of the fetal heart rate changes. However, late fetal heart rate decelerations were associated with a significantly greater fall, after the uterine contraction, in the mean concentration of fetal cerebral oxyhaemoglobin of 0.52μmol/100g (SD 0.25) (P 〈 0.001) and a significantly greater rise in the mean concentration of deoxyhaemoglobin of 0.36 pmol/100 g (SD 0.35) (P 〈 0.01).Conclusion Late fetal heart rate decelerations are associated with a significant decrease in cerebral oxygenation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1995.tb09018.x
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  • 4
    Electronic Resource
    Electronic Resource
    The effect of maternal oxygen administration on human fetal cerebral oxygenation measured during labour by near infrared spectroscopy (1994)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 101 (1994), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To test the hypothesis that intrapartum maternal oxygen administration increases fetal cerebral oxygenation during normal labour.Design A prospective study comparing changes in fetal cerebral concentrations of oxyhaemo- globin, deoxyhaemoglobin and cerebral blood volume measured by near infrared spectroscopy, before, during and after maternal oxygen administration using a 60% Ventimask.Setting Teaching hospital obstetric unit.Subjects Ten term fetuses during uncomplicated labour.Results Maternal oxygen administration for 15 min resulted in a significant increase in the mean concentration of fetal cerebral oxyhaemoglobin (0.78 μmol (SD 0.42) 100 g-1 brain tissue, P 〈 0.001) and a significant decrease in the mean concentration of deoxyhaemoglobin (0.80 μmol (SD 0.51) l00 g-1, P 〈 0.00l). These changes were associated with a significant increase in the calculated mean cerebral oxygen saturation from 43.9 % (SD 6.3) to 57.3 % (SD 5.6) (P 〈 0.001). The maximum rise in cerebral oxyhaemoglobin concentration occurred at a mean of 10.7 min (SD 3.9) following commencement of oxygen administration. On returning to air breathing these changes reversed. There were no changes in cerebral blood volume.Conclusion Maternal oxygen administration during normal labour leads to a significant rise in fetal cerebral oxygenation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1994.tb13152.x
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  • 5
    Electronic Resource
    Electronic Resource
    Relation between frequency of uterine contractions and human fetal cerebral oxygen saturation studied during labour by near infrared spectroscopy (1994)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 101 (1994), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To investigate the effect of the frequency of uterine contractions on fetal cerebral oxygenation, using near infrared spectroscopy.Design An observational study relating changes in the fetal cerebral concentrations of oxyhaemoglobin and deoxyhaemoglobin, measured from the start of one contraction to that of the next, to the time interval between contraction peaks observed by external tocography.Setting A teaching hospital obstetric and neonatal unit.Subjects Ten term fetuses during labour.Results Changes in cerebral oxyhaemoglobin concentration were positively, and in deoxyhaemoglobin negatively, correlated with the time interval between contractions (P 〈 0.001). A mean contraction interval of 2.3 min was found below which the concentration of oxyhaemoglobin usually fell and that of deoxyhaemoglobin rose, indicating a fall in cerebral haemoglobin saturation. Conversely, longer contraction intervals were associated with findings indicative of a rise in cerebral haemoglobin saturation.Conclusion Short contraction intervals (〈 2.3 min) were associated with a decrease, and longer contraction intervals with an increase in fetal cerebral oxygen saturation. Contractions occurring repeatedly at intervals less than 2.3 min are likely to result in progressive cerebral desaturation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1994.tb13008.x
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  • 6
    Electronic Resource
    Electronic Resource
    The effect of maternal pushing on fetal cerebral oxygenation and blood volume during the second stage of labour (1995)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To measure the effect of maternal pushing during the second stage of labour on fetal cerebral oxygenation and blood volume.Design A prospective study comparing changes in the fetal cerebral concentrations of oxy-haemoglobin, deoxyhaemoglobin and cerebral blood volume, before and during maternal pushing in the second stage of labour.Setting Teaching hospital obstetric unit.Subjects Ten term fetuses during labour.Results Following the onset of maternal pushing, mean cerebral deoxyhaemoglobin concentration increased by a mean of 0.79 (SD 0.59) μmol.100 g-1, (P 〈 0.01) without any consistent change in the oxyhaemoglobin concentration. These changes were associated with a significant decrease in the calculated mean cerebral oxygen saturation from a mean of 46.8% (SD 8.6) to 38.1% (SD 5.2) (P 〈 0.01). Pushing was also associated with a significant increase in the mean cerebral blood volume, which rose by a mean of 0.33 ml. 100 g-1 (SD 0.37) (P 〈 0.05).Conclusion Maternal pushing during the second stage of labour leads to a significant decrease in fetal cerebral oxygenation, together with an increase in cerebral blood volume.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1995.tb11316.x
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