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  • 1
    Online Resource
    Online Resource
    Computational methods for optimizing distributed systems (1984)
    Orlando : Academic Press
    Details Availability
    Keywords: Differential equations, Parabolic Numerical solutions ; Boundary value problems Numerical solutions ; Distributed parameter systems ; Geometry, Riemannian ; Distributed parameter systems ; Boundary value problems Numerical solutions ; Differential equations, Parabolic Numerical solutions ; Differential equations, Parabolic Numerical solutions. Boundary value problems ; Numerical solutions. Distributed parameter systems ; Distributed parameter systems. Optimal control ; Distributed parameter systems ; MATHEMATICS ; Differential Equations ; Partial ; Boundary value problems ; Numerical solutions ; Differential equations, Parabolic ; Numerical solutions ; Electronic books ; Electronic books ; Optimierung ; System mit verteilten Parametern ; Numerisches Verfahren ; Optimale Kontrolle ; Randwertproblem ; Parabolische Differentialgleichung ; Numerisches Verfahren ; System mit verteilten Parametern ; Kontrolltheorie ; Parabolische Differentialgleichung ; Numerisches Verfahren ; Optimale Kontrolle ; Randwertproblem ; Optimale Kontrolle ; Randwertproblem ; Parabolische Differentialgleichung ; Numerisches Verfahren ; System mit verteilten Parametern ; Kontrolltheorie ; Parabolische Differentialgleichung ; Numerisches Verfahren ; Optimale Kontrolle ; Randwertproblem
    Description / Table of Contents: Computational methods for optimizing distributed systems
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource (XIII, 317 Seiten)
    Edition: Elsevier e-book collection on ScienceDirect
    ISBN: 9780126854800 , 0080956785
    Series Statement: Mathematics in science and engineering 173
    URL: http://www.sciencedirect.com/science/book/9780126854800
    URL: http://www.sciencedirect.com/science/bookseries/00765392/173
    URL: https://www.sciencedirect.com/science/bookseries/00765392/173
    URL: http://www.sciencedirect.com/science/book/9780126854800
    URL: https://www.sciencedirect.com/science/book/9780126854800
    RVK:
    SK 920
    RVK:
    SK 915
    Language: English
    Note: Literaturverzeichnis: Seite 301-312
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  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of the superconducting thin film of HgBa2Ca2Cu3O8+δ (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 68 (1996), S. 1723-1725 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: HgBa2Ca2Cu3O8+δ (Hg-1223) superconducting thin films of about 0.3 μm in thickness have been successfully synthesized. The process involves depositing films (∼ 1 μm thickness) of Ba2Ca2Cu3Ox on a SrTiO3 substrate by pulse laser ablation technique and implanting mercury ions into this deposited film, followed by annealing at oxygen atmosphere. The films so obtained show a relatively wide superconducting transition temperature up to 118 K, as determined magnetically, which is similar to that of underdoping bulk Hg-1223. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.115887
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  • 3
    Electronic Resource
    Electronic Resource
    Improvement of beamline 4B9A and results of an X-ray diffraction experiment (1998)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 503-505 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: 4B9A is a focusing and monochromatic photon beam at the BSRF, which was constructed in 1990. During the second phase of the BSRF program, the surface of the cylindrical mirror has been coated with Pt, covering the original Ni, and the monochromator has been upgraded. The maximum photon energy extends to 11 keV and the intensity has increased about tenfold with respect to the previous intensity at 6 keV. Synchrotron X-ray diffraction patterns for the Hg-1223 (HgBa2Ca2Cu3O8+δ) superconducting bulk and thin film have been measured at 1.54014 Å. Results indicate that the bulk and film can be indexed as possessing tetragonal symmetry; lattice parameters a = 3.856 Å and c = 15.851 Å for the bulk Hg-1223 compound, and a = 3.8517 Å and c = 15.8511 Å for the film. Their structures are similar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049597014477
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  • 4
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    A single-station spectral model of the monthly median foF2 over Chongqing, China (2009)
    Details
    Publication Date: 2019-11-04
    Description: Hourly values of the critical frequency of the ionospheric F region, foF2, obtained at Chongqing ionospheric observatory (geographic 29.50N, 106.40E), China, during the interval of 1977 to 1997 (solar cycle 21 and 22) have been used to investigate the dependence of the monthly median foF2 on solar activity and geomagnetic activity, and to construct single-station model (SSM) using Fourier expansion. The results of the present analysis show that there is a significant nonlinear relationship between monthly median foF2 and sunspot number R especially at daytime in each month and nighttime in summer. Furthermore, introducing geomagnetic index Ap further improves the description of variation of monthly median foF2, and the standard deviations decrease also dependently on time and month. Thus the complex influence of solar activity and geomagnetic activity may be approximately expressed by a general multiple nonlinear function at Chongqing station, China. The basic aim of this paper is to show that considering the nonlinear influence both of solar activity and geomagnetic activity improves the monthly median model. The SSM is in good agreement with observations, with standard deviation 0.65MHz, while IRI model has a lower accuracy with standard deviation 0.96MHz.
    Description: JCR Journal
    Description: open
    Keywords: solar cycle variation ; single station model ; geomagnetic index ; monthly median foF2 ; 04. Solid Earth::04.05. Geomagnetism::04.05.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
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    Causes of Low Frequency North Atlantic SST Variability in a Coupled GCM (2005)
    American Geophysical Union
    Details
    Publication Date: 2021-05-19
    Description: The low frequency sea surface temperature (SST) variability in the North Atlantic is studied using the Center for Ocean-Land-Atmosphere Studies (COLA) anomaly coupled general circulation model. The main focus is placed on the relative roles of stable and unstable coupled feedbacks in inducing the low frequency SST variability in various regions of the North Atlantic. To examine this question, a recently developed coupling technique, interactive ensembles, is applied to reduce the strength of “weather noise” in the model and isolate the atmospheric feedback to boundary forcing.
    Description: Published
    Keywords: Sea surface temperature
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Format: 602657 bytes
    Format: application/pdf
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  • 6
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    A Shallow-CISK-Deep-Equilibrium Mechanism for The Interaction Between Large-Scale Convection and Large-Scale Circulations In The Tropics (2005)
    American Meteorological Society
    Details
    Publication Date: 2021-05-19
    Description: In this paper, the circulations driven by deep heating and shallow heating are investigated through analytically solving a set of linear equations and examining circulations simulated by a dry primitive equation model. Special emphasis is placed on the low-level mass (moisture) convergence associated with the forced circulation and the maintenance of the shallow and deep heat sources. It is found that the forced circulation driven by shallow heating is more likely to be trapped horizontally near the heating area but relatively extended in the vertical. As a consequence, diabatic heating can not balance adiabatic cooling due to upward motion. At the levels slightly above the top of the heating, a negative vertical gradient of temperature perturbation appears. For the atmosphere driven by deep heating, however, the temperature perturbation cannot accumulate because the heating signals propagate away very fast, allowing an approximate equilibrium between the convective diabatic heating and adiabatic cooling due to upward motion. The converged moisture associated with circulation driven by shallow heating exceeds the amount needed to maintain the heat source. However, the circulation driven by deep heating does not feed back effectively to the moisture convergence, and thus can not be self-sustaining.
    Description: Center for Ocean-Land-Atmosphere Studies - Calverton
    Description: Published
    Keywords: Atmospheric circulation
    Repository Name: AquaDocs
    Type: Journal Contribution , Refereed , Article
    Format: 637515 bytes
    Format: application/pdf
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  • 7
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    Survivin Inhibitors Mitigate Chemotherapeutic Resistance in Breast Cancer Cells by Suppressing Genotoxic Nuclear Factor-{kappa}B Activation [Drug Discovery and Translational Medicine] (2018)
    The American Society for Pharmacology and Experimental Therapeutics
    Details
    Publication Date: 2018-06-09
    Description: Therapeutic resistance developed after chemotherapy and aggressive metastasis are the major causes of cancer-related death in patients with triple-negative breast cancer (TNBC). Survivin is the smallest member of the inhibitor-of-apoptosis proteins (IAPs) family, which plays critical roles in cell division and cell survival. High expression levels of survivin have been associated with therapeutic resistance in various cancers. We recently developed a novel small-molecule survivin inhibitor mimicking the IAP-binding motif of second mitochondria-derived activator of caspase, which showed high potency in promoting survivin degradation. Here, we show that survivin inhibitor MX106/MX107 suppresses TNBC cell proliferation. Moreover, MX106/MX107 synergized with chemotherapeutic drugs or radiation and significantly enhanced tumoricidal efficacy of genotoxic treatments. Mechanistically, MX106/MX107 induced degradation of XIAP and/or cIAP1, which inhibited nuclear factor B (NF- B) activation by genotoxic agents. Treatment with MX106/MX107 alone did not activate alternative NF- B signaling in breast cancer cells, which is likely attributable to their selective potency in degrading survivin in these cells. In addition, survivin degradation by MX106/MX107 dramatically increased abnormal mitotic spindle formation and cell division failure, which led to cell cycle arrest in breast cancer cells. Overall, our study suggests that combination treatment of TNBC using survivin inhibitors MX106/MX107 with cytotoxic chemotherapeutic drugs can achieve significantly improved therapeutic efficacy, which depends on MX106/MX107-mediated inhibition of genotoxic NF- B activation.
    Print ISSN: 0022-3565
    Electronic ISSN: 1521-0103
    Topics: Medicine
    Published by The American Society for Pharmacology and Experimental Therapeutics
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of high hydrostatic pressure on phase composition and microstructure in Au-28 at. % Ge alloy/GaAs contacts (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 7231-7238 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Effects of external hydrostatic pressure up to 7 kbar on the Au-Ge binary phase diagram and on the arsenic sublimation are evaluated by thermodynamic calculations. Experimental observations in the eutectic Au-28 at. % Ge/GaAs contacts which were annealed at vacuum and in a 7 kbar argon gas, respectively, are taken as illustrative examples for the comparison with the calculated results. It is concluded that pressures up to 7 kbar shift only slightly the phase boundaries in the Au-Ge phase diagram that were obtained in standard conditions (1 atm) and a pure argon gas with a pressure of 7 kbar acts as a good capsulation to prevent species As from sublimation. The measurements indicate that the film/GaAs interface and the film surface in the contacts annealed at 7 kbar are rich in Ge and are morphologically smooth. © 1994 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.358004
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  • 9
    Electronic Resource
    Electronic Resource
    Surface roughness effect on surface impedance of superconductors (1994)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 76 (1994), S. 3669-3672 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The measured values of microwave surface resistance and reactance of a superconductor have generally three contributions from (1) the intrinsic properties, (2) the internal defects, and (3) the external surface roughness. In this paper, we formulate the increased factor of surface resistance and reactance of superconductors using Morgan's square-grooves model and with the consideration that the current flows along the irregular surface. Numerical results obtained using a finite difference method are presented together with fitted closed-form formulas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.357430
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  • 10
    Electronic Resource
    Electronic Resource
    Quasielastic neutron scattering and molecular dynamics simulation studies of the melting transition in butane and hexane monolayers adsorbed on graphite (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 107 (1997), S. 5186-5196 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Quasielastic neutron scattering experiments and molecular dynamics (MD) simulations have been used to investigate molecular diffusive motion near the melting transition of monolayers of flexible rod-shaped molecules. The experiments were conducted on butane and hexane monolayers adsorbed on an exfoliated graphite substrate. For butane, quasielastic scattering broader than the experimental energy resolution width of 70 μeV appears abruptly at the monolayer melting point of Tm=116 K, whereas, for the hexane monolayer, it appears 20 K below the melting transition (Tm=170 K). To facilitate comparison with experiment, quasielastic spectra calculated from the MD simulations were analyzed using the same models and fitting algorithms as for the neutron spectra. This combination of techniques gives a microscopic picture of the melting process in these two monolayers which is consistent with earlier neutron diffraction experiments. Butane melts abruptly to a liquid phase where the molecules in the trans conformation translationally diffuse while rotating about their center of mass. In the case of the hexane monolayer, the MD simulations show that the appearance of quasielastic scattering below Tm coincides with transformation of some molecules from trans to gauche conformations. Furthermore, if gauche molecules are prevented from forming in the simulation, the calculated incoherent scattering function contains no quasielastic component below Tm. Modeling of both the neutron and simulated hexane monolayer spectra below Tm favors a plastic phase in which there is nearly isotropic rotational diffusion of the gauche molecules about their center of mass, but no translational diffusion. The elastic scattering observed above Tm is consistent with the coexistence of solid monolayer clusters with a fluid phase, as predicted by the simulations. For T/Tm≥1.3, the elastic scattering vanishes from the neutron spectra where the simulation indicates the presence of a fluid phase alone. The qualitative similarities between the observed and simulated quasielastic spectra lend support to a previously proposed "footprint reduction" mechanism of melting in monolayers of flexible, rod-shaped molecules. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.474881
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