Note: Front Cover -- Bacterial Physiology -- Copyright Page -- Table of Contents -- Contributors -- Preface -- Chapter 1. Chemistry of the Bacterial Cell -- I. Introduction -- II. Form and Size -- III. Chemical Composition of the Cell -- IV. Direct Methods of Cytology -- V. Indirect Methods of Cytology -- Chapter 2. The Structure of the Bacterial Cell -- I. Cell Structure -- II. The Spores of Bacteria -- III. Vegetative Multiplication -- IV. Cell and Environment -- Chapter 3. Inheritance, Variation, and Adaptation -- I. The Gene Theory -- II. Genetic Variation -- III. Characteristics of Bacterial Mutants -- IV. Interclonal Variation -- V. Variation and Adaptation: Recapitulation -- Chapter 4. Growth of Bacteria -- I. Introduction -- II. Quantitative Studies of Bacterial Growth -- III. Growth and Population Cycle of a Bacterial Culture -- IV. Conclusion -- Chapter 5. Physical Factors Affecting Growth and Death -- I. Temperature -- II. Hydrogen Ion Concentration and Osmotic Pressure -- III. Surface Tension -- IV. Oxidation-Reduction Potential -- V. Radiations -- VI. Surface and Other Forces Determining the Distribution of Bacteria in Their Environment -- Chapter 6. Chemical Factors Affecting Growth and Death -- I. Introduction -- II. Chemical Injury to Active Proteins -- III. Dynamics of Disinfection -- IV. Dynamics of Bacteriostasis -- V. Bacterial Resistance -- VI. Types of Antibacterial Agents -- Chapter 7. Bacterial Nutrition-Chemical Factors -- I. General Outlook -- II. The Major Bacterial Growth Factors -- Chapter 8. Bacterial Enzymes and the Theory of Action -- I. Introduction -- II. Historical Aspects -- III. Nomenclature and Classification -- IV. Coenzymes and Related Compounds -- V. Special Methods Used in the Isolation and Study of Bacterial Enzymes -- VI. Theory of Enzyme Action -- VII. Various Factors Controlling Enzymatic Activity. , VIII. Origin and Concentration of Enzymes -- IX. Discussion of Various Groups of Enzymes -- Chapter 9. Anaerobic Dissimilation of Carbohydrates -- I. Introduction -- II. Nature of Anaerobic Dissimilation of Carbohydrates -- III. Early Views on Fermentation -- IV. Glycolysis -- V. Polysaccharides -- Chapter 10. Bacterial Oxidations -- I. Introduction -- II. Some Thermodynamic and Kinetic Approaches -- III. Reversible Oxidation-Reduction Systems of Biological Importance -- IV. Activating Proteins (Dehydrogenase) -- V. Types of Oxidation Enzymes -- VI. Inhibitors of Oxidation Enzymes -- VII. Coupled Oxidation-Reduction Systems: Krebs' Tricarboxylic Acid Cycle -- VIII. Aerobic Phosphorylations -- IX. Pathways of Biological Oxidation-Reductions. The Pasteur Effect -- X. "Oxidation-Reduction Potentials" in Bacteria -- XI. Bacterial Respiration -- XII. Respiration of Growing Cells and of Resting Cells -- XIII. Regulatory Mechanisms of Respiration -- XIV. Life without Oxygen. The Anaerobic Bacteria -- Chapter 11. Autotrophic Assimilation of Carbon Dioxide -- I. Introduction -- II. Chemoautotrophic Bacteria -- III. Photosynthetic Assimilation of Carbon Dioxide -- Chapter 12. Assimilation of Carbon Dioxide by Heterotrophic Bacteria -- I. Introduction -- II. Early Concepts of Function of CO2 -- III. Carbon Dioxide Assimilation and Concepts of Autotrophism and Heterotrophism -- IV. Types of CO2 Assimilation -- V. Replacement of Carbon Dioxide -- VI. Importance of Heterotrophic Assimilation of Carbon Dioxide in Biology -- Chapter 13. Organic Nitrogen -- I. Introduction -- II. Breakdown of Protein -- III. Breakdown of Amino Acids -- IV. Decarboxylation of Amino Acids -- V. Deamination of Amino Acids -- VI. Transamination -- VII. Racemization -- VIII. Biosynthesis of Amino Acids -- IX. Amino Acid Assimilation -- Chapter 14. Biological Nitrogen Fixation. , I. Biogeochemistry of Nitrogen -- II. Agents of Fixation -- III. Properties of the Enzyme System -- IV. Chemical Pathway of Fixation -- V. Comparative Biochemistry of Nitrogen Fixation -- Chapter 15. Mineral Metabolism -- I. Introduction -- II. Purification of Media -- III. Mineral Elements Required for Growth -- IV. Mineral Elements in Bacterial Enzymes -- V. Mineral Elements for Pigments and Antibiotics -- Chapter 16. The Comparative Biochemistry of Molecular Hydrogen -- I. Comparative Biochemistry -- II. Autotrophic and/or Heterotrophic Bacteria -- III. Other Acceptors of Hydrogen -- IV. The Liberation of Molecular Hydrogen -- V. Special Functions of Hydrogenase -- Chapter 17. Assimilation by Bacteria -- I. Introduction -- II. Manometric Observations on Assimilation -- III. Influence of Poisons on Assimilation -- IV. Carbon Balances in Assimilation Studies -- V. Oxidative Assimilation During Growth -- VI. Polysaccharide and Other Syntheses -- VII. Assimilation of Nitrogen -- Chapter 18. Degradation and Synthesis of Complex Carbohydrates -- I. Introduction -- II. Bacterial Polysaccharides -- III. Mechanisms of Synthesis -- IV. General Conclusions -- Chapter 19. Significance of Autotrophy for Comparative Physiology -- Chapter 20. Luminous Bacteria -- I. Introduction -- II. General Characteristics and Physiology -- III. Luminescence as a Reaction Rate Tool in Biology -- IV. General Implications -- V. Conclusion -- BIBLIOGRAPHY -- SUBJECT INDEX -- MICROORGANISM INDEX.

Note: Intro -- Contents -- Preface -- Part I: Theory / Electron-Gated Ion Channels -- 1. Introduction -- 1-1. The electron-gating model -- 1-2. Electron gating of a sodium channel -- 1-3. Timing -- 1-4. Sodium channel current -- 1-5. Sensitivity -- 1-6. Amplification and negative conductance -- 1-7. Model parameters -- 2. Developing A Model -- 2-1. A single electron two-site model -- 2-2. Amplification -- 2-3. A small force constant -- 2-4. Calculating frequencies -- 2-5. Amplification by NH3 inversion resonance -- 2-6. A voltage dependent amplification factor -- 2-7. The amplification energy window -- 2-8. NH3 inversion frequency reduction -- 3. The SetCap Model -- 3-1. A circuit model for two-site electron tunneling -- 3-2. Defining a capacitance factor -- 3-3. Displacement capacitance -- 3-4. Time-constant capacitance -- 3-5. Displacement energy -- 3-6. Energy well depth -- 3-7. The SETCAP model for N tunneling sites -- 4. Amplified Electron Tunneling and the Inverted Region -- 4-1. Amplification and the Marcus inverted region -- 4-2. The Q10 temperature factor -- 4-3. Time constant -- 4-4. Contact resistance -- 4-5. Tunneling resistance -- 4-6. Electron tunneling site-selectivity -- 4-7. The amplification energy window and the inverted region -- 5. Gating and Distortion Factors -- 5-1. Sodium channel inactivation gate leakage -- 5-2. Ion channel gating -- 5-3. Inactivation gating and open-gate distortion -- 5-4. Sodium channel activation gates and distortion -- 5-5. Potassium channel gating and distortion -- 5-6. Edge distortion of inactivation gating -- 5-7. Multistate gating -- 6. Characterization and Validation -- 6-1. Electron gating model equations -- 6-2. Finite-range rate constants -- 6-3. Open-channel probability range and time constant -- 6-4. Rate curves using voltage-sensitive amplification -- 7. Flux Gating In Na+ and K+ Channels. , 7-1. Sodium channel flux gating -- 7-2. Sodium channel inactivation flux gating -- 7-3. Potassium channel flux gating -- 7-4. The influx gating latch-up effect -- 8. Far Sites, Near Sites, and Back Sites -- 8-1. Ion channel mapping -- 8-2. Far sites for inactivation, calcium signaling and memory -- 8-3. Near sites on the S4 -- 8-4. Back sites and hyperpolarization -- 8-5. Gating current -- 8-6. Charge immobilization -- 8-7. A calcium channel oscillator model using far sites -- 9. Electron-Gate K+ Channels -- 9-1. Activation and inactivation of Kv channels -- 9-2. Structural constraints for activation gating -- 9-3. Influx gating latch-up and TEA+sensitivity -- 9-4. K/Na selectivity ratio -- 9-5. C-type inactivation gating -- 9-6. Coupling between tunnel-track electrons -- 9-7. Kinetics and inactivation depend on far sites -- Part II: Experimental Microwave Investigation -- 10. Microwave Thermal Fluorescence Spectroscopy -- 10-1. Microwave spectroscopy for caged proteins -- 10-2. Microwave spectra for Blue Fluorescent Protein -- 10-3. Matching frequencies -- 10-4. Estimating parameters and sensitivity -- 10-5. Arginine and lysine hot spots -- 10-6. Calcium oscillators - microwave sensitivity -- 10-7. The first excited vibrational state -- 10-8. Mode switching at infrared frequencies -- Appendix -- A. Geometric calculations for an or-helix -- B. Time constant for a tunneling distance r -- Final Comments -- A brief review of the findings -- References -- Index.