Publication Date:
2018-02-17
Description:
Physical basis of amyloid fibril polymorphism Physical basis of amyloid fibril polymorphism, Published online: 16 February 2018; doi:10.1038/s41467-018-03164-5 Amyloid fibril structures can display polymorphism. Here the authors reveal the cryo-EM structures of several different fibril morphologies of a peptide derived from an amyloidogenic immunoglobulin light chain and present a mathematical analysis of physical factors that influence fibril polymorphism.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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