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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 1076 (1991), S. 1-8 
    ISSN: 0167-4838
    Keywords: (P. sativum chloroplast) ; Disulfide bridge ; NADP-malate dehydrogenase ; Protein structure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2016-09-16
    Description: Targeting the RB-E2F pathway in breast cancer Oncogene 35, 4829 (15 September 2016). doi:10.1038/onc.2016.32 Authors: J Johnson, B Thijssen, U McDermott, M Garnett, L F A Wessels & R Bernards
    Print ISSN: 0950-9232
    Topics: Medicine
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  • 3
    Publication Date: 2022-06-09
    Description: Transnational access (TNA) allows cross‑border, short‑term and frequently free‑of‑charge access to world-class research facilities, to foster collaborations and exchanges of experience. Specifically, TNA aims to encourage open science and innovation and to increase the efficient and effective use of scientific infrastructure. Within EPOS, the European Plate Observing System, the Volcano Observatories and Multi‑scale Laboratories communities have offered TNA to their high‑quality research facilities through national and European funding. This experience has allowed the definition, design, and testing of procedures and activities needed to provide transnational access in the EPOS context. In this paper, the EPOS community describes the main objectives for the provision of transnational access in the EPOS framework, based on previous experiences. It includes practical procedures for managing transnational access from a legal, governance, and financial perspective, and proposes logistical and technical solutions to effectively execute transnational access activities. In addition, it provides an outlook on the inclusion of new thematic communities within the TNA framework, and addresses the challenges of providing market‑driven access to industry.
    Language: English
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 4
  • 5
    Publication Date: 2023-05-09
    Description: The EPOS Multi-scale Laboratories (MSL) community includes a wide range of world-class solid Earth science laboratory infrastructures and as such it provides a multidisciplinary- and coherent platform for both virtual access to data and physical access to sophisticated research equipment. The MSL laboratories provide facilities for highly-specialized experimental research that results in experimental and analytical data underlying publications about phenomena ranging from the molecular to the continental scale. From the perspective of the intended FAIRness of these laboratory data, the challenge for the MSL community has been to develop a data management paradigm that on one hand acknowledges the uniqueness of many of the data collections involved, and on the other hand maximizes their findability through metadata dissemination via common standards into larger cross-disciplinary communities. Furthermore, besides provenance information about the data themselves, harmonized information about research groups and experimental assets must be considered as increasingly important for feeding the network relations that may help in making sense of scientific impact. As part of the MSL Data Publication Chain, the MSL community has developed a standardised workflow that allows easy metadata exchange based on common formats (e.g., flavors of DCAT-AP, DataCite 4.x, and ISO19115), whereas at the same time it integrates dedicated ontologies to give access to the richness of specialized terminology with respect to the MSL subdomains (e.g., analogue modelling, paleomagnetism, rock physics, geochemistry). Community developed controlled vocabularies act as the binding agent between data, equipment, and the experiment itself, while at the same time processing tools like a user-friendly metadata editor and a CKAN-based MSL data publication portal provide the building blocks for the chain towards cross-disciplinary sustainable dissemination. We will demonstrate how the MSL data management paradigm exploits both the strength of controlled terminology and the availability of good agnostic common standards in an approach for managing heterogeneous data coming from long tail communities.
    Type: info:eu-repo/semantics/conferenceObject
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  • 6
    Publication Date: 2023-08-29
    Description: Understanding earth materials is critical to foster technological and environmental development, as well as to advance in Earth-science disciplines, like mineral- and rock-physics, as well as material-oriented (bio)geochemistry. EXCITE, a large-scale infrastructure project supported by the European Union’s Horizon-2020 program comprising 15 European institutions for electron and X-ray microscopy, enables free-of-charge Trans-National Access (TNA) to high-end microscopy and microanalysis facilities to develop community-driven technological advancements on Earth materials. The WP5 of EXCITE aims to facilitate mechanisms and procedures to provide TNA to world-class facilities, specifically addressing new, non-expert or early career users worldwide. By definition, TNA involves a researcher conducting science at a research facility located in a country different from the one in which they are working. The EXCITE TNA programme provides access to 24 imaging facilities in 9 countries. Access is provided on a per-call basis, and is granted following a proposal review process. During the first two TNA calls, almost 150 scientific projects have been supported. Two more calls from both academia and industry users will allow access to facilities until April 2024. Analytical techniques and scientific expertise offered include X-ray micro- to nano-tomography, EPMA, FIB-SEM, TEM, as well as SEM-based imaging, element mapping, EBSD, cathodoluminescence and other specialized imaging tools. Our contribution will present the architecture of the EXCITE-TNA programme and outcomes of the user evaluations, which clearly demonstrate the success of Excellence-driven TNA programmes as a strategic asset of the European research scenario, allowing networking and collaboration and favoring education & outreach in geosciences.
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 7
    Publication Date: 2024-02-12
    Description: The Multi-scale Laboratories (MSL) are a network of European laboratories bringing together the scientific fields of analogue modeling, paleomagnetism, experimental rock and melt physics, geo-chemistry and microscopy. MSL is one of nine (see below) Thematic Core Services (TCS) of the European Plate Observing System (EPOS). The overarching goal of EPOS is to establish a compre-hensive multidisciplinary research platform for the Earth sciences in Europe. It aims at facilitating the integrated use of data, models, and facilities, from both existing and new distributed pan European Research Infrastructures, allowing open access and transparent use of data.The TCS MSL network allows researchers to collaborate with other labs and scientists. By becoming part of the rapidly growing TCS MSL network, new laboratories are offered a platform to showcase their research data output, laboratory equipment and information, and the opportunity to open laboratories to guest researchers through the Transnational Access (TNA) program.The EPOS Multi-scale laboratories offer researchers a fully operational data publication chain tailored to the specific needs of laboratory research, from a bespoke metadata editor, through dedi­cated, (domain­specific) data repositories, to the MSL Portal showcasing these citable data publica-tions. During this process the data publications are assigned with digital object identidiers (DOI), published with open licenses (e.g. CC BY 4.0) and described with standardized and machine-read-able rich metadata (following the FAIR Principles to make research data Findable, Accessible, Interoperable and Reusable. The TCS MSL is currently working on linking these data publications to the EPOS Central Portal1, the main discovery and access point for European multi-disciplinary data, and on increasing the number of connected data repositories.
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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