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  • 1
    Online Resource
    Online Resource
    Latest Ordovician to Early Silurian Shale Gas Strata of the Yangtze Region, China (2023)
    Singapore : Springer Nature Singapore | Singapore : Imprint: Springer
    Details Availability
    Keywords: Geology. ; Sedimentology. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Jangtsekiang-Tafel ; Schiefergas ; Erdgasgeologie ; Lagerstättenkunde ; Stratigraphie ; Graptolithen ; Untersilur ; Oberordovizium ; Muttergestein ; Chronostratigraphie ; Lithostratigraphie ; Biostratigraphie ; Ordos-Becken ; Sequenzstratigraphie ; Formation ; Geologie ; Vorkommen ; TOC ; Sichuan ; Beckensediment ; Schwarzschiefer ; Sedimentationsbecken ; Methanlagerstätte
    Description / Table of Contents: Introduction -- Geological Setting of the Ordovician and Silurian Strata of the Yangtze Platform -- Ordovician to Silurian Shale Gas-Bearing Strata from the Yangtze Region -- Distribution Pattern of the Ordovician–Silurian Shale Gas-Bearing Strata in the Yangtze Region -- Regional and Global Correlation of the Latest Ordovician to Early Silurian Shale Gas-Bearing Strata -- Paleogeography and Paleoenvironment Across the Ordovician– Silurian Transition in the Yangtze Region -- Gamma Log Responses Through the Ordovician–Silurian Black Shale Graptolite Zonal Succession in the Middle and Upper Yangtze Regions -- Volcanic Ash Deposition and Organic Matter Enrichment in the Black Shales of the Wufeng–Lungmachi Formations in the Yangtze Region -- Appendix Plates and Explanation. .
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource(IX, 237 p. 205 illus., 129 illus. in color.)
    Edition: 1st ed. 2023.
    ISBN: 9789819931347
    URL: https://doi.org/10.1007/978-981-99-3134-7
    DOI: 10.1007/978-981-99-3134-7
    Language: English
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  • 2
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    Impact of sedimentation history for As distribution in Late Pleistocene-Holocene sediments in the Hetao Basin, China (2020)
    Springer Berlin Heidelberg
    Details
    Publication Date: 2023-06-08
    Description: Purpose: To understand the impact of geochemical sedimentation history for arsenic (As) distribution in the sediment profiles of the Hetao Basin, we (1) evaluated sediments provenance and variations of weathering intensities, (2) attempted to reconstruct the depositional environments, and (3) explored the As and Fe speciation in the sediments. Combining the information above, different sedimentation facies were distinguished in the vertical profiles.
    Description: Methods: Two sediments cores were drilled up to 80 m depth. Major and trace element compositions, including rare earth elements (REE), were analyzed. Carbon isotope ratios (δ13Corg) of embedded organic matter in the sediments were analyzed by isotope ratio mass spectrometry (IR-MS). Arsenic and Fe speciation of the sediments were determined by sequential extractions.
    Description: Results and discussion: The similar REE geochemistry of rocks from the Lang Mountains and sediments in the Hetao Basin indicated that the sediments originated from the Lang Mountains. The C/N ratio (~ 4 to ~ 10) in combination with δ13Corg (− 27‰ to −2 4‰) suggested that sediments were mainly deposited in aquatic environments. The unconfined aquifer equaled the lacustrine deposit with less intensive weathering during last glacial maximum (LGM). Here, the As content (average, 5.4 mg kg−1) was higher than in the aquifer sediments below (average, 3.6 mg kg−1).
    Description: Conclusion: Higher content of releasable As in combination with paleolake-derived organic matter aquifer sediments probably contributes to higher groundwater As concentration in the unconfined aquifer. This study provides the first insight into the impact of sedimentation history on As distributions in sediment profiles in the Hetao Basin.
    Description: China Scholarship Council http://dx.doi.org/10.13039/501100004543
    Keywords: ddc:551.9 ; Sediment basin ; Sedimentation history ; Arsenic provenance ; Weathering intensities ; Organic carbon isotopic signature ; Arsenic speciation
    Language: English
    Type: doc-type:article
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  • 3
    Electronic Resource
    Electronic Resource
    The genetic epidemiology of psoriasis vulgaris in Chinese Han (2002)
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 41 (2002), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The aim of this study was to explore the effects of genetic factors on the onset of psoriasis vulgaris and to develop a possible genetic model of psoriasis in Chinese Han.Methods Data for 1043 patients with psoriasis vulgaris were obtained by questionnaire. Complex segregation analysis and heritability were performed using Penrose's method, Falconer's method, and the epi info 6.0 and sage-regtl programs.Results (1) For male and female patients, the peak ages of initial onset were 30–39 and 10–19 years, respectively, with the mean age of initial onset being 27.69 ± 12.32 years in males and 23.26 ± 12.56 years in females. (2) Of 1043 patients with psoriasis, 326 (31.26%) were reported to have a family history of psoriasis. The onset for males with a family history of psoriasis was earlier than that for those without a family history (P 〈 0.01). The morbidities of first-degree relatives were 7.67% in patients with type I psoriasis and 5.27% in patients with type II (P 〈 0.01), and those of second-degree relatives were 1.04% in type I and 0.24% in type II (P 〈 0.01). (3) The onset of psoriasis was earlier in females than in males in type I psoriasis (P 〈 0.01), but this was not the case in type II (P 〉 0.05). (4) The prevalence of psoriasis in first- and second-degree relatives of the proband with psoriasis was 7.24 and 0.95%, respectively; higher than that in the general population (0.146%). (5) The heritability of psoriasis in first- and second-degree relatives was 67.04 and 46.59%, respectively. The Mendelian, no-major-gene and environment model was rejected by complex segregation analysis.Conclusion Psoriasis vulgaris follows a pattern of polygenetic or multifactorial inheritance rather than single-gene inheritance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-4362.2002.01596.x
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  • 4
    Electronic Resource
    Electronic Resource
    Real-time RT-PCR analysis of loblolly pine (Pinus taeda) arabinogalactan-protein and arabinogalactan-protein-like genes (2005)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Physiologia plantarum 124 (2005), S. 0 
    Details
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Arabinogalactan-proteins (AGPs) are a class of large hydroxyproline-rich glycoproteins (HGRPs) found in almost all plant species, and have been implicated in various plant growth and developmental processes including xylogenesis. A total of six AGP-like genes or gene families have been cloned from differentiating pine xylem. In this study, seven different members of the ptaAGP5 gene family with between 54% and 73% similarity at the amino acid level were newly identified. Gene-specific primers were designed and relative transcript levels of 11 loblolly pine AGP and AGP-like genes were examined using real-time reverse transcription-polymerase chain reaction (RT-PCR) analysis. Expression was examined in different tissues: earlywood and latewood; xylem from two populations; drought-stressed and well-watered roots; compression, opposite and vertical wood; and in vitro cultured cells induced for lignification. The different loblolly pine AGP and AGP-like genes showed varying expression patterns under the different conditions, suggesting different functions for each loblolly pine AGP. The results from this study also suggest that some AGPs are associated with xylogenesis, but not with lignification, and that different xylem AGPs probably have different functions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3054.2005.00479.x
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  • 5
    Electronic Resource
    Electronic Resource
    HLA-DQA1 and DQB1 alleles are associated with genetic susceptibility to psoriasis vulgaris in Chinese Han (2004)
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 43 (2004), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Psoriasis vulgaris is a chronic skin disorder characterized by infiltration of inflammatory elements, keratinocyte hyperproliferation and altered differentiation. Although the pathogenesis of psoriasis is not fully understood, there is solid evidence of a susceptibility locus in the human leukocyte antigen (HLA) region.Objectives  To investigate whether HLA-DQA1 and DQB1 alleles are associated with genetic susceptibility to psoriasis vulgaris in Chinese Han.Patients and methods  The polymerase chain reaction–sequence-specific primer (PCR-SSP) method was used to analyse the distribution of HLA-DQA1 and DQB1 alleles in 189 patients with psoriasis and 273 healthy controls.Results  The HLA-DQA1*0104 (OR = 2.33, P = 0.0001154, Pc = 2.0 × 10−3), DQA1*0201 (OR = 3.36, P 〈 1.0 × 10−7, Pc 〈 1.0 × 10−6), DQB1*0201 (OR = 1.64, P = 0.0192, Pc 〉 0.05) and DQB1*0303 (OR = 1.55, P = 0.0377, Pc 〉 0.05) alleles were more prevalent in patients with psoriasis vulgaris than in controls, and HLA-DQA1*0501 (OR = 0.30, P = 0.0000039, Pc 〈 4.0 × 10−5) alleles were less prevalent. The HLA-DQA1*0104 (OR = 2.42, P = 0.0001159, Pc 〈 2.0 × 10−3), DQA1*0201 (OR = 3.74, P 〈 1.0 × 10−7, Pc 〈 1.0 × 10−6) and DQA1*0501 (OR = 0.30, P = 0.0000374, Pc 〈 4.0 × 10−4) alleles were only associated with type I psoriasis. HLA-DQA1*0104 and DQA1*0201 were more prevalent in patients with or without a family history of psoriasis. However, the DQA1*0501 allele was only more prevalent in patients without a family history of psoriasis.Conclusion  HLA-DQA1*0104 and DQA1*0201 alleles may be psoriasis susceptibility genes or may be in close linkage with the susceptibility genes. The HLA-DQA1*0501 allele seems to have a protective effect against the development of psoriasis vulgaris in Chinese Han. There may be a difference in genetic background between psoriasis patients with and without a family history of psoriasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4632.2004.02098.x
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  • 6
    Electronic Resource
    Electronic Resource
    Polymorphisms associated with the factor IX gene in Chinese people (1999)
    Oxford UK : Blackwell Science Ltd
    Haemophilia 5 (1999), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2516.1999.00360.x
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  • 7
    Electronic Resource
    Electronic Resource
    Frequent use of tobacco and alcohol in Chinese psoriasis patients (2002)
    Oxford, UK : Blackwell Science Ltd
    International journal of dermatology 41 (2002), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background This study aimed to explore smoking and drinking as risk factors in psoriasis.Methods Data collected from 789 psoriasis patients and 789 healthy controls were analyzed to determine whether there was an association between smoking/drinking and psoriasis.Results The proportion of male psoriasis patients using tobacco and alcohol was much higher than that of the control group (P 〈 10−6), whereas no statistical differences were found between female smokers and the control group. In general, heavy smokers were more likely to have severe psoriasis.Conclusion Tobacco use in patients is correlated with psoriasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-4362.2002.01595.x
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  • 8
    Electronic Resource
    Electronic Resource
    Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon (2007)
    [s.l.] : Nature Publishing Group
    Nature 449 (2007), S. 96-100 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Self-renewal and differentiation are cardinal features of stem cells. Asymmetric cell division provides one fundamental mechanism by which stem cell self-renewal and differentiation are balanced. A failure of this balance could lead to diseases such as cancer. During asymmetric division of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature06056
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  • 9
    Electronic Resource
    Electronic Resource
    The Pathogen of Crown Gall Disease on Flowering Cherry and its Sensitivity to Strain K1026 (2000)
    Springer
    European journal of plant pathology 106 (2000), S. 475-479 
    Details
    ISSN: 1573-8469
    Keywords: flowering cherry ; crown gall disease ; biological control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Six strains of crown gall bacteria were isolated from flowering cherry. It was revealed by Otten paper electrophoresis that of the six strains, only BYH18-4 possessed the octopine type Ti plasmid, the remainder having nopaline type Ti plasmid. BYH5-1 was identified by physiological and biochemical tests to be Agrobacterium tumefaciens (originally biovar 1). The other five were A. rhizogenes (originally biovar 2). It was demonstrated with Stonier's method of double layer medium that flowering cherry crown gall bacteria exhibited different sensitivities to agrocin produced by biocontrol strain K1026. Strain K1026 on greenhouse-grown sunflower seedlings exerted a relatively potent inhibitory action on flowering cherry crown gall bacteria. Artificial inoculation showed that K1026 produced 67–99% inhibition of flowering cherry crown gall disease, compared with the treatment of inoculation with crown gall bacteria only.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008734120555
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  • 10
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    Balancing self-renewal and differentiation by asymmetric division: Insights from brain tumor suppressors in Drosophila neural stem cells (2012)
    Wiley-Blackwell
    In: BioEssays
    Details
    Publication Date: 2012-04-15
    Description: Balancing self-renewal and differentiation of stem cells is an important issue in stem cell and cancer biology. Recently, the Drosophila neuroblast (NB), neural stem cell has emerged as an excellent model for stem cell self-renewal and tumorigenesis. It is of great interest to understand how defects in the asymmetric division of neural stem cells lead to tumor formation. Here, we review recent advances in asymmetric division and the self-renewal control of Drosophila NBs. We summarize molecular mechanisms of asymmetric cell division and discuss how the defects in asymmetric division lead to tumor formation. Gain-of-function or loss-of-function of various proteins in the asymmetric machinery can drive NB overgrowth and tumor formation. These proteins control either the asymmetric protein localization or mitotic spindle orientation of NBs. We also discuss other mechanisms of brain tumor suppression that are beyond the control of asymmetric division. Drosophila neuroblasts represent an excellent model system to study the molecular mechanisms of asymmetric divisions during stem cell self-renewal and how defects in this system lead to tumourigenesis.
    Print ISSN: 0265-9247
    Electronic ISSN: 1521-1878
    Topics: Biology , Medicine
    Published by Wiley-Blackwell
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