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  • 1
    Electronic Resource
    Electronic Resource
    Evaluation of Amberlite XAD-4 for the recovery of fenitrothion from water
    Amsterdam : Elsevier
    Journal of Chromatography A 172 (1979), S. 388-393 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(00)90980-4
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  • 2
    Electronic Resource
    Electronic Resource
    Recovery of fenitrothion from water using amberlite resin XAD-7
    Amsterdam : Elsevier
    Journal of Chromatography A 177 (1979), S. 385-389 
    Details
    ISSN: 0021-9673
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)96340-X
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  • 3
    Electronic Resource
    Electronic Resource
    Bioelectrochemical determination of lactic and malic acids in wine
    Amsterdam : Elsevier
    Talanta 41 (1994), S. 917-923 
    Details
    ISSN: 0039-9140
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0039-9140(94)E0044-R
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  • 4
    Electronic Resource
    Electronic Resource
    Phosphate determination in foodstuffs using a plant tissue electrode
    Amsterdam : Elsevier
    Food Chemistry 44 (1992), S. 291-297 
    Details
    ISSN: 0308-8146
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0308-8146(92)90053-5
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  • 5
    Electronic Resource
    Electronic Resource
    X-ray crystallographic characterization of 10,11-dihydro-5H-dibenz[b, f ]azepine-5-carboxamide (1992)
    Springer
    Journal of chemical crystallography 22 (1992), S. 177-183 
    Details
    ISSN: 1572-8854
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The structure of the title compound was determined by the direct methods and refined by fullmatrix least-squares to anR of 0.041 for 1467 diffractometer-measured reflections. The dihedral angle between the aromatic-ring mean planes is 128° and the central seven-membered azepine ring adopts a boat conformation, as usual for compounds of this type. X-ray powder diffraction of the compound indicates that the crystal selected appears to be representative of the sample as a whole.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01186254
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  • 6
    Electronic Resource
    Electronic Resource
    Rearrangements of bcl-6, bcl-2, c-myc and 6q deletion in B-diffuse large-cell lymphoma: Clinical relevance in 71 patients (1998)
    Springer
    Annals of oncology 9 (1998), S. 55-61 
    Details
    ISSN: 1569-8041
    Keywords: B-DLCL ; clinical correlations ; genetic lesions ; outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: B-diffuse large-cell lymphomas (DLCL) have been associated with some molecular lesions, but the role of such lesions as prognostic markers is still controversial. This report concerns an investigation of the frequency and clinical correlation of bcl-6, bcl-2, c-myc rearrangements and 6(q) deletions in B-DLCL. Patients and methods: The presence of these genetic lesions was analyzed in samples of lymph nodes or bone marrow collected at diagnosis in 71 patients with B-DLCL, all treated with an antracycline-containing chemotherapy regimen. Results: Rearrangement of bcl-6 was found in 11 patients (15%), rearranged bcl-2 in 12 (17%), 6(q) deletions in 10 patients (14%) and c-myc rearrangement in four (6%). Patients with rearranged bcl-6 tended to have a more aggressive disease than patients with germ-line bcl-6 (intermediate–high/high risk according to IPI criteria: 73% vs. 43%), but there were no differences in three-year survival rates (62% vs. 42%) between the two groups. The numbers of involved extranodal sites were similar in patients with rearranged and those with germ-line bcl-6. Patients with bcl-2 rearrangement appeared to have a less aggressive disease than those with germ-line bcl-2 (low/low–intermediate risk 75% vs. 47%) and a slightly better three-year survival rate (70% vs. 41%) but again the difference was not significant. Both groups with or without 6(q) deletion had similar clinical characteristics and outcomes. The four patients with c-myc rearrangement had aggressive disease and did poorly. Conclusions: The analysis of molecular lesions in B-DLCL may be useful for a better diagnostic definition; however, in this study we were unable to show that the evaluated genetic lesions had a significant impact on clinical outcome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008201729596
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  • 7
    Electronic Resource
    Electronic Resource
    Analysis of microsatellite instability in chronic lymphoproliferative disorders (1996)
    Springer
    Annals of hematology 72 (1996), S. 67-71 
    Details
    ISSN: 1432-0584
    Keywords: Microsatellite instability ; Genomic instability ; Chronic lymphocytic leukemia ; Richter's syndrome ; Lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Microsatellite instability (MSI) represents one specific pattern of genomic instability and is one of the genetic lesions most frequently detected in human neoplasia. Although MSI has been found to be associated with a wide variety of solid cancers, its involvement in lymphoid malignancies is virtually unexplored. In this study, we have investigated the presence of MSI in chronic lymphoproliferative disorders by comparing the pattern of nine microsatellite repeats (two tetranucleotides, two trinucleotides, and five dinucleotides) on autologous germline and tumor DNA of 23 patients, including 17 with B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL), four with hairy cell leukemia, one with lymphoplasmacytoid lymphoma, and one with T-cell chronic lymphocytic leukemia. All samples at diagnosis displayed a germline pattern of the microsatellites examined, thus suggesting that MSI is not involved in the pathogenesis of these lymphoproliferations. Also, no microsatellite alterations were observed in consecutive samples of B-CLL/SLL obtained from the same patient at various stages of the disease both before and after chemotherapy. Conversely, alterations in 3/9 microsatellite repeats were detected in one case of Richter's syndrome which had evolved from a pre-existent B-CLL/SLL phase. Overall, the low frequency of MSI among chronic lymphoproliferative disorders adds further weight to the common view that the mechanisms and patterns of genomic instability in lymphoid neoplasia differ markedly from those commonly observed in solid cancers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00641310
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  • 8
    Electronic Resource
    Electronic Resource
    Analysis of microsatellite instability in chronic lymphoproliferative disorders (1996)
    Springer
    Annals of hematology 72 (1996), S. 67-71 
    Details
    ISSN: 1432-0584
    Keywords: Key words Microsatellite instability ; Genomic instability ; Chronic lymphocytic leukemia ; Richter's syndrome ; Lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Microsatellite instability (MSI) represents one specific pattern of genomic instability and is one of the genetic lesions most frequently detected in human neoplasia. Although MSI has been found to be associated with a wide variety of solid cancers, its involvement in lymphoid malignancies is virtually unexplored. In this study, we have investigated the presence of MSI in chronic lymphoproliferative disorders by comparing the pattern of nine microsatellite repeats (two tetranucleotides, two trinucleotides, and five dinucleotides) on autologous germline and tumor DNA of 23 patients, including 17 with B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL), four with hairy cell leukemia, one with lymphoplasmacytoid lymphoma, and one with T-cell chronic lymphocytic leukemia. All samples at diagnosis displayed a germline pattern of the microsatellites examined, thus suggesting that MSI is not involved in the pathogenesis of these lymphoproliferations. Also, no microsatellite alterations were observed in consecutive samples of B-CLL/SLL obtained from the same patient at various stages of the disease both before and after chemotherapy. Conversely, alterations in 3/9 microsatellite repeats were detected in one case of Richter's syndrome which had evolved from a pre-existent B-CLL/SLL phase. Overall, the low frequency of MSI among chronic lymphoproliferative disorders adds further weight to the common view that the mechanisms and patterns of genomic instability in lymphoid neoplasia differ markedly from those commonly observed in solid cancers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00641310
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  • 9
    Electronic Resource
    Electronic Resource
    High-performance liquid chromatography of fenitrothion and seven derivatives — A study of their recovery from water using XAD resins as compared with organic solvents (1981)
    Springer
    Chromatographia 14 (1981), S. 333-336 
    Details
    ISSN: 1612-1112
    Keywords: Fenitrothion and derivatives ; High-performance liquid chromatography ; XAD resins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The separation of fenitrothion and seven possible degradation products namely aminofenitrothion, fenitrooxon, S-methylfenitrothion, formylfenitrothion, hydro-xymethylfenitrothion, nitrocresol and thiocresol, was accomplished on a non-polar stationary phase with a hydrophylic mobile phase. Operating parameters were optimized to achieve maximum resolution. Recovery of the eight chemicals was done using Amberlite resins XAD-2, −4, and −7. Comparison was made with the conventional solvent extraction technique using methylene chloride and ethyl acetate, respectively. In general, recoveries were good with the resins except for formylfenitrothion, hydroxymethylfenitrothion and thiocresol. An improvement in recovery was observed for S-methylfenitrothion with ethyl acetate but methylene chloride was generally less efficient than the resins. Recovery from environmental water was successful.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02259230
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  • 10
    Electronic Resource
    Electronic Resource
    Ciliary neurotrophic factor-induced gene expression in human neuroblastoma cell lines (1995)
    Springer
    Neurochemical research 20 (1995), S. 675-680 
    Details
    ISSN: 1573-6903
    Keywords: CNTF ; neuroblastoma cells ; differentiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have analyzed the response of the human neuroblastoma cell lines SK-N-SH (clone SY5Y) and SK-N-BE to the ciliary neurotrophic factor CNTF. In both cell lines CNTF induced the expression of the mRNA for two transcription factors, c-fos and NGF1A. The induction was rapid and transient reaching a maximum between 30 and 60 min after exposure to CNTF and subsequently declining. The level of induction of both c-fos and NGF1A mRNAs was much higher in SK-N-BE neuroblastoma cells compared to the SY5Y. Both cells express comparable levels of the transcript for the CNTF receptor-alpha. This mRNA was down regulated after 5 days of CNTF stimulation in both cell lines. CNTF also induced increased levels of the transcript for the growth cone associated protein GAP43 in SK-N-BE, but not in SY5Y cells. Induction followed a slower kinetic compared to that observed for c-fos and NGF1A. In fact, the GAP43 mRNA levels increased during 2 days of exposure to CNTF. Morphological analysis of CNTF treated cells showed that SK-N-BE undergo significant differentiation in response to CNTF (increased number of cells with neurites and increased neurite length) while SY5Y did not show appreciable morphological differentiation. These data shows that CNTF may elicit different response in neuroblastoma cell lines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01705535
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