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  • 1
    Online Resource
    Online Resource
    London :Oneworld Publications,
    Keywords: Brain. ; Electronic books.
    Description / Table of Contents: It has been remarked that if the brain were so simple we could understand it, we would be so simple we couldn't. Commencing with a brief history of neuroscience, from the ancient practice of drilling holes in the head to relieve headaches to the latest results from MRI and CT scans, this accessible guide sets out to explore exactly what we do know about the brain. Including the most up-to-date research on the cerebral processes behind a wide array of human activity - from our capacity for language to how we remember - this lively and entertaining introduction assumes no previous scientific knowledge and offers a tantalizing glimpse into man's most complex organ. Ammar Al-Chalabi is Honourary Consultant Neurologist at King's College Hospital, and a Senior Lecturer at the Institute of Psychiatry, London. R. Shane Delamont is a Consultant Neurologist at King's College Hospital, and Martin Turner is Wellcome Fellow in Neurology at The Institute of Psychiatry. All three have extensive experience of teaching the key principles of neuroscience, and between them their specialist fields of expertise cover all of the main areas of contemporary brain research.
    Type of Medium: Online Resource
    Pages: 1 online resource (207 pages)
    Edition: 2nd ed.
    ISBN: 9781780740539
    Series Statement: Beginner's Guides
    DDC: 612.82
    Language: English
    Note: Intro -- Title Page -- Copyright -- Contents -- Preface -- Acknowledgements -- List of plates -- Section 1: Introducing the brain -- Introduction: In the beginning . . . -- 1. The history of the human brain - so it does do something after all -- 2. The evolution of the brain - how the brain came to be -- 3. Nerves - the body electric -- Section 2: Making a brain and mind from one cell -- 4. The development of the brain - growing a nervous system -- 5. The anatomy of the brain - understanding the grand plan -- 6. The supporting structures of the brain - what a brain needs to survive -- 7. The development of behaviour and reasoning - learning to be human -- Section 3: Having and using a brain as an adult -- 8. Consciousness - the ultimate mystery -- 9. Memory - putting the past into perspective -- 10. Sleep - bedtime for the brain -- 11. The motor system - making movement and motion -- 12. The sensory system - feel the world -- 13. The visuospatial system - making light work -- 14. Language, hearing and music - making sense of sound -- 15. Emotions and the limbic system - the heart and the head -- 16. Investigating the brain - discovering the diagnosis -- 17. Living for ever - the fountain of youth -- 18. The end? -- Appendix: Eric Chudler's brain facts and figures -- Glossary -- Further reading -- Index.
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  • 2
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Women due for vacuum extraction were randomly allocated to delivery using one of two soft cups (Silc or Silastic) or two new design rigid cups (New Bird or O'Neil). Traction forces were recorded continuously and higher values were reached with the rigid than the soft cups (median 15.8, range 7.5.19.7 vs 11.1, 7.2.15.1 kg, P 〈 0.01). Selection of the most appropriate vacuum cup for each clinical situation should take into account that the flexible cups are associated with less cosmetic disfigurcment but have a lower capacity for traction.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Genomic imprinting brings about allele-specific silencing according to parental origin. Silencing is controlled by cis-acting regulatory regions that are differentially marked during gametogenesis and can act over hundreds of kilobases to silence many genes. Two candidate imprinting control regions ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Genomic imprinting results in allele-specific silencing according to parental origin. Silencing is brought about by imprinting control regions (ICRs) that are differentially marked in gametogenesis. The group of imprinted transcripts in the mouse Gnas cluster (Nesp, Nespas, Gnasxl, Exon 1A and ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A mutation was introduced into the kinase domain of the syk gene by homologous recombination in embryonic stem (ES) cells (Fig. \a). Two such targeted clones were used to establish mouse strains carrying the mutation and mice heterozygous for the mutation (syk+/) were intercrossed to generate ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A null mutation was introduced into either one or both copies of the vav gene in embryonic stem (ES) cells by homologous recombination (Fig. la, b) and chimaeric mice, designated vav+/ or vavf, were generated. Immunoblot analysis of lys-ates from vav+/ and vav ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 115 (1994), S. 463-470 
    ISSN: 1432-2072
    Keywords: Erectile response ; Rigiscan ; Sexual arousal ; Alpha-2 adrenoceptor antagonist ; Systolic BP ; Heart rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of a new alpha-2 adrenoceptor antagonist on erectile function was assessed in 12 normal volunteers (mean age 28.7, range 20–42), using a double blind, placebo controlled design with two doses of drug and three testing sessions. The drug was administered by intravenous infusion and erectile responses to erotic fantasy and films were monitored by a Rigiscan device. Four effects of the drug were observed; (i) an increase in spontaneous erections; (ii) increased subjective ratings of sexual arousal,before presentation of erotic stimuli; (iii) increased duration of erectile response to erotic stimuli; and (iv) increases in systolic BP and HR both before and during erotic stimulation. These effects were largely restricted to the high dose of the drug. Adverse effects of the drug were minimal.
    Type of Medium: Electronic Resource
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  • 8
    Publication Date: 2012-02-01
    Description: Author(s): Leopoldo R. Gómez, Ari M. Turner, Martin van Hecke, and Vincenzo Vitelli Nonlinear sound is an extreme phenomenon typically observed in solids after violent explosions. But granular media are different. Right when they jam, these fragile and disordered solids exhibit a vanishing rigidity and sound speed, so that even tiny mechanical perturbations form supersonic shocks. ... [Phys. Rev. Lett. 108, 058001] Published Tue Jan 31, 2012
    Keywords: Soft Matter, Biological, and Interdisciplinary Physics
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 9
    Publication Date: 2016-09-30
    Description: The Group on Earth Observations Biodiversity Observation Network (GEO BON) is developing the Essential Biodiversity Variables (EBVs) as the key variables needed, on a regular and global basis, to understand and monitor changes in the Earth's biodiversity. A subset of these EBVs can be derived from space-based remote sensing, within this paper referred to as remotely sensed EBVs (RS-EBVs). Given the global, periodic and standardized character of satellite remote sensing measures, RS-EBVs may be seen as easier to generate than non-remotely sensed EBVs, which have to be assembled from disparate and local sources of information. Particularly because they are global and periodic, RS-EBVs are of special relevance for monitoring the state of and changes to biodiversity, notably the structure and function of ecosystems. If well developed, RS-EBVs can provide key information for global biodiversity assessments as well as for national governments to meet their obligations under the Convention on Biological Diversity (CBD), in particular to formulate and implement appropriate management responses to biodiversity losses. However, the relevance and usage of globally produced RS-EBVs in wide-scale ecological modelling, such as in species distribution and abundance studies or in ecosystem integrity analyses, are still to be demonstrated, in particular when it comes to deriving biodiversity indicators for policy making and implementation. The biodiversity community at large, from those conducting scientific ecological studies to those involved in the development of remote sensing applications for biodiversity monitoring, can gain value from RS-EBVs, but doing so requires close cooperation with space agencies. Effective interaction is only likely to result if the biodiversity community understands how space agencies determine their observation and product requirements. To develop these requirements, space agencies need to precisely specify the physical measurements for their spaceflight instruments, as well as the algorithmic approaches, to generate RS-EBV products from these measurements. Here, we address the biodiversity community to discuss the role space agencies should play in the development of EBVs arising from satellite remote sensing. Importantly, we explain the necessity for translating the observational needs of the biodiversity community into specific satellite remote sensing measurement and algorithm requirements. By summarizing the prerequisite conditions that are required for obtaining a collective and strong engagement of space agencies in the co-development of RS-EBVs, we aim to facilitate collaborative efforts between the biodiversity community and the space agencies, which can ultimately contribute to a global and comprehensive biodiversity knowledge system. Outline of the overall process by which remotely sensed essential biodiversity variables should be developed and matured. The Group on Earth Observations Biodiversity Observation Network (GEO BON) is developing the Essential Biodiversity Variables (EBVs) as the key variables needed, on a regular and global basis, to understand and monitor changes in the Earth's biodiversity. With the emergence of satellite missions with ensured observational continuity and free and open data policies, space agencies provide, over the long term, a unique means to monitor, understand and predict the status and trends of biodiversity. A strong engagement of Space Agencies in the co-development of EBVs requires both a community buy-in of the EBVs (and of the subset of remotely sensed EBVs) and an endorsement by a recognized authority such as the Convention on Biological Diversity (CBD). These prerequisite conditions are necessary to obtain a firm commitment of CEOS and its Member Space Agencies to actively participate in the development of the RS-EBV data products and related algorithms and to align the acquisition scenarios of their satellite assets to the observation needs of the biodiversity community.
    Electronic ISSN: 2056-3485
    Topics: Architecture, Civil Engineering, Surveying , Biology
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