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  • 1
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms -- Physiology. ; Microbiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (363 pages)
    Edition: 1st ed.
    ISBN: 9780080579870
    Series Statement: Issn Series
    DDC: 576.1/1
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 27 -- Copyright Page -- Contents -- Contributors -- Chapter 1. Mode of Action of Clinically Important Antifungal Drugs -- I. Introduction -- II. The nucleus as the primary target -- III. The cell membrane as the primary target -- IV. Finale -- V. Acknowledgements -- References -- Chapter 2. Microbial Cyanide Metabolism -- I. Introduction -- II. Bacterial cyanide production -- III. Fungal cyanogenesis -- IV. Cyanogenesis by photosynthetic micro-organisms -- V. Cyanide degradation -- VI. Concluding remarks -- References -- Chapter 3. Bacterial Oxidation of Methane and Methanol -- I. Introduction -- II. Oxidation of methane to methanol -- III. Oxidation of methanol to formaldehyde -- IV. Energy transduction during the oxidation of methane and methanol -- V. Acknowledgements -- References -- Chapter 4. Occurrence, Biochemistry and Physiology of Phenazine Pigment Production -- I. Introduction -- II. Natural occurrence and some properties of phenazines -- III. Biosynthesis -- IV. Secondary metabolism and the physiological significance of phenazine production -- V. Acknowledgements -- References -- Chapter 5. Nature and Development of Phenotypic Resistance to Amphotericin B in Candida albicans -- I. Introduction -- II. Mode of action of amphotericin -- III. Assessment of amphotericin sensitivity -- IV. Interactions between amphotericin, sterols and surface structures of Cundida albicans -- V. Changes in the cell wall during the stationary phase of culture -- VI. The effects of oxidation and reduction -- VII. Nature of the cell-wall barrier and its modification by reducing agents -- VIII. Incorporation of glucose into the (1 → 3)-β-glucan fraction -- IX. Actions of analogues of glucose -- X. Conclusions and in conclusion -- References -- Note added in proof -- Author Index -- Subject Index.
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  • 2
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms -- Physiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (321 pages)
    Edition: 1st ed.
    ISBN: 9780080579917
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 31 -- Copyright Page -- Contents -- Contributors -- Chapter 1. The TOL Plasmids: Determinants of the Catabolism of Toluene and the Xylenes -- I. Introduction -- II. Biochemistry of the pathway -- Ill. Organization of the catabolic genes -- IV. Regulation of catabolic genes -- V. Recombination and transposition -- VI. Growth of TOL strains on benzoate ("benzoate curing") -- VII. Evolution of catabolic pathways -- VIII. Use of TOL plasmid genes in construction of novel strains and vectors -- IX. Epilogue -- X. Acknowledgements -- References -- Chapter 2. Recent Research into the Physiology of Mycobacterium leprae -- I. Introduction -- II. Growth of Mycobacterium leprae -- III. The cell envelope -- IV. Metabolism in Mycobacterium leprae -- V. Interaction of Mycobacterium leprae with host cells -- VI. Possible applications -- VII. Conclusions -- VIII. Acknowledgements -- References -- Chapter 3. Magnetotactic Bacteria: Microbiology, Biomineralization, Palaeomagnetism and Biotechnology -- I. Introduction -- II. Occurrence -- Ill. Methods of study -- IV. Physiology -- V. Fine structure -- VI. Biomineralization -- VII. Magnetotaxis -- VIII. Palaeomagnetism -- IX. Biotechnological applications -- X. Addendum -- XI. Acknowledgements -- References -- Chapter 4. Microbial Stress Proteins -- I. Introduction -- II. What are stress proteins? -- III. Stress proteins are highly conserved -- IV. Induction of stress-protein synthesis -- V. Acquired thermotolerance -- VI. Immune response -- VII. Protein assembly and translocation -- VIII. Summary -- IX. Acknowledgements -- References -- Chapter 5. Microbial Anaerobic Respiration -- I. Introduction -- II. General overview of the organization and function of respiratory chains -- III. Methanogenesis -- IV. Sulphate as a respiratory oxidant. , V. Fumarate respiration -- VI. Oxides of nitrogen as respiratory oxidants -- VII. Other anaerobic oxidants -- VIII. Conclusions -- References -- Author index -- Subject index.
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  • 3
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms. ; Microbiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (375 pages)
    Edition: 1st ed.
    ISBN: 9780080579894
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 29 -- Copyright Page -- Contents -- Contributors -- Chapter 1. Hydrogen Metabolism in Rhizobium: Energetics, Regulation, Enzymology and Genetics -- I. Introduction -- II. Regulation -- III. Enzymology -- IV. Energetics -- V. Genetics -- VI. Acknowledgements -- References -- Chapter 2. The Physiology and Biochemistry of Pili -- I. Introduction -- II. Nomenclature -- III. Classification -- IV. High-resolution studies on pilus structure -- V. Organization and expression of pilin genes -- VI. Structure-function relationships of pili proteins -- VII. Acknowledgements -- References -- Chapter 3. Carboxysomes and Ribulose Bisphosphate Carboxylase/Oxygenase -- I. Introduction -- II. Distribution and structure of carboxysomes -- III. Carboxysome composition -- IV. Ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) -- V. Carboxysome function -- VI. Further aspects of carboxysomes -- References -- Chapter 4. Archaebacteria: The Comparative Enzymology of Their Central Metabolic Pathways -- I. Introduction -- II. Archaebacterial pathways of central metabolism -- III. Archaebacterial enzyme diversity -- IV. Structure of archaebacterial enzymes -- V. Concluding remarks -- VI. Acknowledgements -- References -- Chapter 5. Physiology of Lipoteichoic Acids in Bacteria -- I. Introduction -- II. Occurrence and structure -- III. Metabolism -- IV. Cellular location -- V. Biological activities -- VI. Concluding remarks -- VII. Acknowledgements -- References -- Author index -- Subject index.
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  • 4
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms -- Physiology. ; Microbiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (329 pages)
    Edition: 1st ed.
    ISBN: 9780080579863
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 26 -- Copyright Page -- Contents -- Chapter 1. Nitrogen Catabolite Repression in Yeasts and Filamentous Fungi -- I. Introduction -- II. Nitrogen Catabolite Repression in Succharocmyces Cerevisiae -- III. Nitrogen Metabolite Repression in Filamentous Fungi -- IV. Acknowledgements -- References -- Note Added in Proof -- Chapter 2. Sexual Agglutination in Chlamydomonads -- I. Introduction -- II. The Mating System -- III. The mating process -- IV. The Specificity of Sexual Agglutination -- V. Dynamics of Sexual Agglutination -- VI. Concluding Remarks -- References -- Chapter 3. The Energy Flow in Bacteria: The Main Free Energy Intermediates and Their Regulatory Role -- I. Introduction -- II. The Energy Circuit in Bacteria -- III. Energy Transduction in the Cytoplasmic Membrane -- IV. Regulation by Energy Intermediates -- V. Homoeostasis in the Magnitude of Free Energy Intermediates -- VI. Conclusions and perspectives -- VII. Acknowledgements -- References -- Chapter 4. Hydrogenase Nitrogenase and Hydrogen Metabolism in the Photosynthetic Bacteria -- I. Introduction -- II. The Organisms -- III. Hydrogen Utilization and Production by Photosynthetic Bacteria -- IV. Hydrogenase -- V. Nitrogenase -- VI. Genetics of Hydrogen Production and Utilization -- VII. Use of Photosynthetic Bacteria as Biological Solar Energy Converters -- VIII. Summary and Prospects -- IX. Acknowledgements -- References -- Note Added in Proof -- Chapter 5. Biochemistry and Physiology of Bioluminescent Bacteria -- I. Introduction -- II. Taxonomy -- III. Biochemistry -- IV. Molecular Biology -- V. Physiology -- VI. Ecology -- VII. Analytical and Clinical Applications -- VIII. Acknowledgements -- References -- Note Added in Proof -- Author Index -- Subject Index.
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  • 5
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms -- Physiology. ; Microbiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (357 pages)
    Edition: 1st ed.
    ISBN: 9780080579856
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 25 -- Copyright Page -- Contents -- Contributors -- Preface -- Chapter 1. Secondary Metabolism and Microbial Physiology -- I. Introduction -- II. The meaning of the terms secondary metabolism and secondary metabolite -- III. Biochemical similarities and differences between primary and secondary metabolism -- IV. What is meant by the term "physiology"? -- V. Areas of physiology in which materials of limited taxonomic distribution might be expected to play a role -- VI. Evidence that some secondary metabolites, distributionally defined, discharge key physiological roles -- VII. Why have physiological roles not been ascribed to more microbial secondary metabolites? -- VIII. Epilogue -- IX. Acknowledgements -- References -- Chapter 2. Physiology of Circadian Rhythms in Micro-Organisms -- I. Introduction -- II. Circadian rhythms in protozoa -- III. Circadian rhythms in unicellular algae -- IV. Circadian rhythms in fungi -- V. General considerations and conclusions -- VI. Acknowledgement -- References -- Chapter 3. Polyol Metabolism in Fungi -- I. Introduction -- II. Enzymes -- III. Mastigomycotina -- IV. Zygomycotina -- V. Ascomycotina and Deuteromycotina -- VI. Basidiomycotina -- VII. Regulation of cytoplasmic pH values in fungi -- VIII. Comment -- References -- Chapter 4. Temperature Profiles of Yeasts -- I. Introduction -- II. The elements of temperature profiles -- III. Types of temperature profiles -- IV. Effects of drugs on the temperature profiles of yeasts -- V. Targets of temperature effects -- References -- Chapter 5. Effects of Alcohols on Micro-Organisms -- I. Why study the effects of alcohols on micro-organisms? -- II. Effects of alcohols on prokaryotic micro-organisms -- III. Effects of alcohols on eukaryotic micro-organisms -- IV. Effects of alcohols on membrane organization. , V. Effects of lipid supplements on alcohol tolerance, growth, survival and fermentation -- VI. Mechanism of inhibition of fermentation by ethanol -- VII. Conclusions and future directions -- VIII. Acknowledgements -- References -- Author Index -- Subject Index -- Cumulative Index of Contributors -- Cumulative Subject Index.
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  • 6
    Online Resource
    Online Resource
    San Diego :Elsevier Science & Technology,
    Keywords: Microorganisms -- Physiology. ; Microbiology. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (285 pages)
    Edition: 1st ed.
    ISBN: 9780080579900
    Series Statement: Issn Series
    Language: English
    Note: Front Cover -- Advances in Microbial Physiology, Volume 30 -- Copyright Page -- Contents -- Contributors -- Chapter 1. Trends and Perspectives in Nitrogen Fixation Research -- I. Background -- II. Chemistry -- III. Biochemistry -- IV. Genetics -- V. Physiology -- VI. Ecology -- VII. Envoi -- References -- Chapter 2. Apomixis in Saccharomyces cerevisiae and Other Eukaryotic Micro- organisms -- I. Introduction: occurrence of apomixis in yeast -- II. The meaning of apomixis in plants, animals and fungi -- III. Apomixis in some eukaryotic micro-organisms -- IV. Inheritance of apomixis in yeasts -- V. Environmental modification of the apomictic phenotype -- VI. Timing of events controlling the manner of nuclear division -- VII. Nucleomitochondrial interactions in facultative apomixis -- VIII. Ecology of apomixis in yeasts -- IX. Concluding remarks -- References -- Chapter 3. Current Trends in Candida albicans Research -- I. Introduction -- II. Genetics -- III. Morphogenesis -- IV. Pathogenesis -- V. Problems in research on Candida albicans -- VI. Summary -- VII. Acknowledgements -- References -- Chapter 4. Circulating Ionic Current in Micro-organisms -- I. Introduction -- II. Measurement of ionic currents -- Ill. Studies on bacteria -- IV. Currents in fungi -- V. Currents in protozoa -- VI. Currents in algae -- VII. Effects of applied voltage and ion gradients -- VIII. Ionic currents and cellular physiology -- IX. Conclusions -- References -- Chapter 5. Autotrophic Nitrification in Bacteria -- I. Introduction -- II. Ecological and economic importance of nitrification -- III. Taxonomy and species diversity -- IV. Biochemistry of nitrifying bacteria -- V. Growth of nitrifying bacteria in liquid culture -- VI. Surface growth -- VII. The effect of oxygen and light on nitrification -- VIII. The effect of pH value on nitrification. , IX. lnhibition of nitrification -- X. Concluding remarks -- XI. Acknowledgements -- References -- Chapter 6. Physiology, Biochemistry and Genetics of Bacterial Glycogen Synthesis -- I. Introduction -- II. Occurrence of glycogen in bacteria -- III. Enzymes involved in synthesis of glycogen -- IV. Characterization of the bacterial glycogen biosynthesic enzymes -- V. Genetic regulation of glycogen biosynthesis in Escherichia coli -- VI. Acknowledgements -- References.
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  • 7
    ISSN: 1432-072X
    Keywords: Methylotrophy ; Thermotolerance ; Chemostat culture ; Methanol limitation ; Metabolic fluxes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Recently we have isolated a number of thermotolerant, spore-forming methylotrophic bacilli in pure culture. With a methanol-limited chemostat culture of strain Ts1, incremental increases in the incubation temperature from 45°C to 62.5°C revealed an optimum with respect to growth yield of 52.5°C, and a maximum of 62.5°C. Similar investigations revealed a pH optimum of 7.5 and a broad growth rate optimum with respect to growth yield. The organism displayed a low maintenance energy requirement and high growth yield (attained simultaneosly with high growth rates) during growth on methanol. Under all conditions of methanol limitation, substrate was oxidized solely to biomass and CO2 and carbon recoveries greater than 90% were manifest. Our data suggested that this resulted from an ability of the organism to precisely adjust its catabolic and anabolic pathways to suit prevailing growth conditions. These results are discussed in relation to previously reported data on thermophiles in both batch and chemostat culture.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-072X
    Keywords: Methylotrophy ; Thermotolerance ; Chemostat culture ; Methanol excess ; Metabolic fluxes ; Overflow metabolites
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Growth of the thermotolerant methylotrophic Bacillus strain TS1 in methanol-limited chemostat culture showed that the substrate was oxidized solely to biomass and CO2. When a pulse of methanol was added to the growth vessel anabolism could be shown to be dissociated from catabolism for a transient period of time. Present data shows that when the organism was grown with a limitation other than carbon, some of the substrate was channelled into metabolite over-production. When the organism was grown under N-limitation 2-oxoglutarate accumulated in the culture medium in small amounts whilst acetate accumulated under all carbon excess conditions. Although the average carbon recovery was 92%, analysis of the culture filtrates for other metabolites failed to show significant amounts of any individual product above those detected in carbon-limited growth comditions. The results are discussed in relation to published data.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-072X
    Keywords: Potassium ; Ammonium ; Bacillus stearothermophilus ; Klebstella pneumoniae ; Chemostat culture ; Growth requirement-pH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The biomass concentration extant in potassiumlimited cultures of either Klebsiella pneumoniae or Bacillus stearothermophilus (when growing at a fixed temperature and dilution rate in a glucose/ammonium salts medium) increased progressively as the medium pH value was raised step-wise from 7.0 to 8.5. Because the macromolecular composition of the organisms did not vary significantly, this increase in biomass could not be attributed to an accumulation of storage-type polymers but appeared to reflect a pH-dependent decrease in the cells' minimum K+ requirement. Significantly, this effect of pH was not eviden with cultures in which no ammonium salts were present and in which either glutamate or nitrate was added as the sole nitrogen source; however, it was again manifest when various concentrations of NH4Cl were added to the glutamate-containing medium. This suggested a functional replacement of K+ by NH 4 + , a proposition consistent with the close similarity of the ionic radii of the potassium ion (1.33 Å) and the ammonium ion (1.43 Å). At pH 8.0, and with a medium containing both glutamate (30 mM) and NH4Cl (100 mM), cultures of B. stearothermophilus would grow without added potassium at a maximum rate of 0.7 h-1. Under these conditions the cells contained maximally 0.1% (w/w) potassium (derived from contaminating amounts of this element in the medium constituents), a value which should be compared with one of 1.4% (w/w) for cells growing in a potassiumlimited medium containing initially 0.5 mM K+. Qualitatively similar findings were made with cultures of K. pneumoniae; and whereas one may not conclude that NH 4 + can totally replace K+ in the growth of these bacteria, it can clearly do so very extensively.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1572-9699
    Keywords: glucose dehydrogenase ; bioenergetics ; growth yield ; enzyme regulation ; chemostat culture ; Acinetobacter calcoaceticus ; Klebsiella aerogenes ; Escherichia coli ; Pseudomonas species
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The regulation of the PQQ-linked glucose dehydrogenase in different organisms is reviewed. It is concluded that this enzyme functions as an auxiliary energy-generating mechanism, because it is maximally synthesized under conditions of energy stress. It is now definitively established that the oxidation of glucose to gluconate generates metabolically useful energy. The magnitude of the contribution of the oxidation of glucose to gluconate via this enzyme to the growth yield of organisms such asAcinetobacter calcoaceticus is not yet clear.
    Type of Medium: Electronic Resource
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