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  • 1
    Electronic Resource
    Electronic Resource
    Telangiectatic pacemaker erythema (2003)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 28 (2003), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2003.01285_1.x
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  • 2
    Electronic Resource
    Electronic Resource
    High levels of interleukin-8, soluble CD4 and soluble CD8 in bullous pemphigoid blister fluid. The relationship between local cytokine production and lesional T-cell activities (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Bullous pemphigoid (BP) is an inflammatory subepidermal blistering disease associated with autoantibodies that recognize hemidesmosomal proteins. In addition to autoantibodies, the cell-mediated immune reaction is considered to play an important part in blister formation. Objectives To investigate some T-cell activation markers and inflammatory cytokines in the blister fluid and sera of patients with BP. Methods We measured soluble CD4 (sCD4) and soluble CD8 (sCD8), which have been, respectively, associated with CD4 and CD8 T-cell activation. Enzyme-linked immunosorbent assays were also used to quantify the production of the leucocyte chemoattractant interleukin (IL) -8 and of the cytokines IL-1α, IL-1β, IL-6, IL-10 and tumour necrosis factor-α in the blister fluid and sera of 11 patients with BP. Results The mean ± SD level of sCD4 in patients’ blisters (42·4 ± 25·0 units mL−1) was significantly elevated (P 〈 0·005) compared with that in their sera (11·2 ± 8·9) and that in the suction blisters of 10 healthy people (11·4 ± 5·4; P 〈 0·005). Mean ± SD IL-8 concentrations in BP blisters (4683·6 ± 3878·1 pg mL−1) were much higher than those in their sera (17·1 ± 18·9; P 〈 0·001), and were very significantly elevated (P 〈 0·005) in comparison with those in suction blisters of healthy persons (512 ± 292). sCD4 levels in BP blisters were inversely related to IL-10 levels (P = 0·03, r2 = 0·85), IL-8 levels were positively related to sCD8 levels (P = 0·01, r2 = 0·54), and IL-1β levels were positively related to sCD8 concentrations (P 〈 0·005, r2 = 0·65). Conclusions The correlations suggest that there is a delicately orchestrated network of cytokines and cell-mediated immunity operating in BP blisters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03894.x
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  • 3
    Electronic Resource
    Electronic Resource
    Observation of electron velocity overshoot in AlxGa1−xAs/GaAs heterostructure insulated-gate field-effect transistors (1990)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 57 (1990), S. 566-568 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The factor γ=1+(RS+RD)/Rds is suggested to modify the expression of effective electron velocity in field-effect transistors (FETs), where RS and RD are the source and drain resistances, respectively, and Rds is the intrinsic drain-to-source resistance. Based on this modified expression ν'eff = 2πLfTγ, where L is the gate length and fT is the cut-off frequency, velocity overshoots were observed clearly at room temperature in AlxGa1−xAs/GaAs heterostructure insulated-gate FETs with both undoped and doped channels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.103622
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  • 4
    Electronic Resource
    Electronic Resource
    Stepped-gate-oxide structure—A new approach for speed enhancement in the gate-controlled photodetector (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 1335-1337 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In this letter, we report a stepped-gate-oxide structure implemented in the gate-controlled photodetector. The experimental results show that a one-order-of-magnitude enhancement in the response speed can be achieved by the use of such a structure owing to the induced transverse electrical field.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.100708
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  • 5
    Electronic Resource
    Electronic Resource
    Observation of capacitive modulation of bipolar current in crystalline silicon gated p-i-n structures (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 1875-1877 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report, for the first time, the experimental observation of capacitive modulation of bipolar current in crystalline silicon devices consisting of a lateral p-i-n channel and an insulated polycrystalline silicon gate. Modulation characteristics of devices with different channel lengths are compared.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101265
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  • 6
    Electronic Resource
    Electronic Resource
    Symplectic symmetry of Hubbard model and η pairing (1995)
    College Park, Md. : American Institute of Physics (AIP)
    Journal of Mathematical Physics 36 (1995), S. 1177-1191 
    Details
    ISSN: 1089-7658
    Source: AIP Digital Archive
    Topics: Mathematics , Physics
    Notes: By means of symplectic group Sp(2M), the symplectic symmetry of the Hubbard model and the η pairing are investigated to approach the eigenstates which have the largest spin multiplicities. The behavior of the off-diagonal long-range order of these eigenstates is examined by the criterion proposed by Yang and the energy diagram of the corresponding eigenvalues is elucidated by the η pairing mechanism. A basis set which is expressible in terms of η and ηa pairings is proposed. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.531363
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  • 7
    Electronic Resource
    Electronic Resource
    Wavelength dependence of carrier-type in reduced BaTiO3:Rh (1998)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 72 (1998), S. 2199-2201 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report that in BaTiO3:Rh the carrier-type depends not only on the postprocessing condition but also on the incident wavelength in two beam coupling. Carriers are the holes for the as-grown sample, and change to electrons for the sample reduced in the atmosphere of 10−14 atm oxygen partial pressure. However, for the sample reduced in the atmosphere of 10−10 atm oxygen partial pressure, the carrier is an electron for the incident wavelength of 514 nm, and a hole for 633 nm. Its absorption, photoinduced absorption, and two beam coupling are investigated and discussed. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.121321
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  • 8
    Electronic Resource
    Electronic Resource
    Invariant Property of the Distribution of Aa1, ..., Aas - Bb1, ..., Bbt-Type Ideal Polymerization (1995)
    s.l. : American Chemical Society
    Macromolecules 28 (1995), S. 2738-2744 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00112a020
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  • 9
    Electronic Resource
    Electronic Resource
    Theoretical study on potential-energy surface of C2N2 (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 108 (1998), S. 2024-2027 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: B3LYP and CCSD(T) (single-point) calculations are performed on structures and interconversion transition states for five C2N2 isomers, i.e., the linear structures NCCN 1, CNCN 2, CNNC 3, and CCNN 4, and the NNC three-membered ring structure with exocyclic C–C bonding 5. A schematic potential-energy surface of the five C2N2 isomers is established. It is shown that the elusive and long searched for isomer 3 lies in a deep potential well against isomerization to the well-studied isomers 1 and 2, while the two transition states, which have been predicted to connect the isomers 1 and 3, are actually associated with the interexchange of the two cyano groups in isomer 2. It is also shown that the experimentally unknown but expectedly important isomer 4 may take an isomerization pathway to the isomer 1 via the intermediate 5, and the isomer 4 also lies in a deep potential well. Both the isomers 3 and 4 may be thermally as stable as the isomer 2. The results presented in this paper may provide useful information for the identification of the two isomers 3 and 4. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.475581
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  • 10
    Electronic Resource
    Electronic Resource
    The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour (2003)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 149 (2003), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  One determining factor of skin colour is the distribution pattern of melanosomes within keratinocytes. Melanosomes in keratinocytes of light skin as in Caucasians are distributed as membrane-bound clusters, whereas the melanosomes in keratinocytes of dark skin as in African/American individuals tend to be larger and distributed individually. It has been shown that melanin content, melanin composition and the size of melanosomes in the human epidermis vary considerably with both ethnicity and chronic sun exposure.Objectives  To assess quantitatively the distribution pattern of melanosomes that have been transferred to keratinocytes in the photoprotected (volar forearm) skin from normal Asian individuals and to compare these data with those from light-skinned Caucasian and dark-skinned African/American individuals.Methods  Electron microscopy was used.Results  We have demonstrated that melanosomes within keratinocytes of Asian skin are distributed as a combination of individual and clustered melanosomes with a proportion of 62·6% vs. 37·4%, respectively. This contrasts with dark and light skin keratinocytes where melanosomes are predominantly individual (88·9%) and clustered (84·5%), respectively. Analysis of mean ± SD melanosome size also revealed a progressive variation in size with ethnicity, melanosomes in dark skin being the largest (1·44 ± 0·67 μm2 × 10−2) followed in turn by those in Asian skin (1·36 ± 0·15 μm2 × 10−2) and Caucasian skin (0·94 ± 0·48 μm2 × 10−2). In addition, it was shown that the melanosomes that are individually distributed tend to have a larger size than the clustered melanosomes.Conclusions  The present data indicate that there may be a size gradient of melanosomes encompassing the global complexion coloration and that the melanosome distribution in keratinocytes of Asian skin is intermediate between that in light Caucasian and dark African/American skin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2003.05473.x
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