Electronic Resource
Springer
International archives of occupational and environmental health
33 (1974), S. 83-97
ISSN:
1432-1246
Keywords:
Lead
;
Sex
;
Biochemical toxicology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Lead (20 and 30 Μg/kg body weight/day) was administered as lead acetate during 3 weeks to human volunteers of both sexes. The following parameters were measured: lead in blood (PbB), erythrocyte δ-aminolaevulinic acid dehydratase activity (ALAD), protoporphyrin IX in the erythrocytes (PPE), δ-aminolaevulinic acid excretion in urin (ALAU) and haemoglobin (Hb). The response and sequence of these parameters were as follows: at first PbB increased and ALAD decreased at the same time within 3 days. In females PPE started to increase after about 2 weeks up to 2 times preexposure values; in males ingesting 20 Μg/kg/day there was no change. Males ingesting 30 Μg/kg/day showed a smaller increase of PPE which appeared after 3 weeks. ALAU only increased temporarily in the first week in males ingesting 30 Μg/kg/day.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00538993
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