ISSN:
0749-1581
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The published data up to 1984 on carbon-carbon coupling constants derived from biosynthetic studies are presented. Nearly 1400 one-, two-, and three-bond carbon-carbon coupling constants, representing 212 compounds are arranged in three Tables. In the first Table the compounds, together with their J (CC) values, are arranged according to their biosynthetic origin. In the second Table couplings over more than one bond are collected. The one-bond couplings are arranged in Table 3, in order of increasing magnitude in each of six categories which, in turn, are based on the formal hybridisation of the coupled carbon atoms. This method of categorisation provides direct access to a vast amount of biosynthetic information and allows the estimation of typical ranges for the various types of (C,C) coupling constants. The magnitude of the carbon-carbon couplings is discussed in terms of factors such as the electronegativity of the substituents, ring size and stereochemical influences. In addition, the applications of carbon-carbon coupling in biosynthetic studies, as well as the experimental methods for obtaining these values, are discussed.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260231204
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