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  • 1
    ISSN: 1432-0584
    Keywords: Key words Thalassemia intermedia ; Erythropoietin ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We report a patient with thalassemia intermedia who developed a mediastinal syndrome due to the growth of paravertebral hematopoietic masses in the posterior mediastinum. Because the patient did not receive blood transfusions due to alloimmunization, she was first treated with human recombinant erythropoietin (escalating low-moderate doses) to recover hemoglobin levels, then in association with radiotherapy to prevent a worsening of her anemia. The mean Hb level dramatically increased and peaked at week 11, to 83 g/l, and remained unchanged before and after radiotherapy (81 versus 78 g/l). Immediately after radiotherapy extramedullary hematopoiesis volume decreased by 16.4%.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0584
    Keywords: Key words Thalassemia ; Chelation ; Desferrioxamine ; Allergy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  In some patients compliance to subcutaneous desferrioxamine therapy is reduced because of allergic symptoms. Effective drug desensitization consists of bringing patients to tolerate the same mode of administration. We evaluated three thalassemic patients with severe allergies to desferrioxamine. Each patient received weekly three prefilled infusors with desferrioxamine 4 g/48 m1/48 h for s.c. therapy. Follow-up was performed for 12 consecutive weeks. During follow-up no allergic events were noted. The s-ferritin levels decreased from 2583 μg/l±485 to 1916 μg/l±275 (mean decrease 25.8%, p=0.038). Compliance to the infusional system was excellent. Our results show that continuous infusion of desferrioxamine using a new infusional delivery system is effective in preventing allergic reactions and in reducing iron overload.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 38 (1992), S. 2137-2146 
    ISSN: 1572-8943
    Keywords: cement industry ; high temperature microcalorimetry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Seit langer Zeit werden in der Zementindustrie Verfahren mit Wärmemessung angewendet. Zur Erforschung der Verschlackungsreaktionen wird DTA verwendet, was jedoch ein dynamisches Verfahren ist und keine Messungen und Berechnungen bezüglich des thermischen Gleichgewichtes erlaubt. Im Gegensatz dazu kann Hochtemperatur-Mikrokalorimetrie zur Messung der Enthalpie von Verschlackungsreaktionen industrieller Rohstoffe dienen. Mit Hilfe der durch diese Methode erlangten Resultate kann das thermische Profil von Verschlackungsreaktionen im Kiln und der Wärmeaustausch im Festmaterial beim Brennen bestimmt werden. Niedertemperatur-Konduktions-Mikrokalorimetrie liefert Informationen über den Hydratationsmechanismus von Zementleim. Unter spezieller Beachtung neuer Methoden, wie z.B. der Hochtemperatur-Mikrokalorimetrie, wird in diesem Artikel ein Überblick über die Anwendungen der Thermoanalyse in der Zementindustrie gegeben.
    Notes: Abstract Methods involving heat measurements have been applied in the cement industry for a long time. Differential thermal analysis (DTA) is used to explain the clinkering reactions, but it is a dynamic method which thus does not allow measurements and calculations of the thermal balance of the reactions to be made. In contrast, high temperature microcalorimetry may be used to measure the enthalpy of the clinkering reactions of industrial raw materials. Results obtained by using this technique allow us to determine the thermal profile of clinkering reactions in the kiln and to quantify the heat exchange in the solid material during its burning. Low temperature conduction microcalorimetry gives information on the hydration mechanism of the cement pastes. In this paper, we review the applications of thermal analysis in the cement industry paying special attention to new methods such as high temperature microcalorimetry.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 9 (1981), S. 63-66 
    ISSN: 1434-0879
    Keywords: Frog calculogenesis ; Oxalate calculi ; Anticalculous substances ; Calculi prophylaxis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rana esculenta tadpoles that are fed spinach develop an oxalic calculogenesis. The addition of cholestyramine, orthophosphate, citrate, allopurinol and tungstate to the tank water prevented calculi formation while succinimide, magnesium oxide, hydrochlorothiazide and tetracycline were ineffective. Methylene blue proved lethal to tadpoles, and its anti-lithogenic activity could not be assessed. These findings, except for the non-effectivness of magnesium oxide, are in agreement with both the theoretical expectations and the results obtained in other experimental models. Experimental frog calculogenesis seems to be a simple and valid method for evaluating anti-lithogenic activity.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 6 (1978), S. 71-75 
    ISSN: 1434-0879
    Keywords: Cystic kidney disease ; Diphenylamine ; Chick oedema
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Chronic intoxication with diphenylamine (DPA), which causes a cystic kidney disease in the rat and the guinea-pig, caused degeneration of the renal tubular epithelium in the chicken. This was similar to but much more serious than that preceding the formation of cysts in the rodents, but did not actually result in cyst formation, probably because of the high mortality rate observed in the birds even at this early stage. In the chicken until now it had been possible to obtain a pattern of renal cysts only with polychlorinated biphenyls (PCB) which also induce the “chick oedema” syndrome. The renal lesions due to DPA in the chicken were similar to those produced by PCB, but were not accompanied by oedema, which suggests that “chick oedema” caused by PCB is not due to renal insufficiency. The differences in the renal lesions noted in the various animal species give credit to the hypothesis that DPA may have two effects on the tubular epitelium, one stimulating cell proliferation and one leading to degeneration. Cysts may be formed only in those species in which there is cell proliferation.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    International urology and nephrology 13 (1981), S. 35-40 
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In two patients with end-stage polycystic kidneys suffering from severe and protracted hematuria recourse was made to therapeutic renal embolization. Hematuria stopped immediately, never to appear again, whilst recanalization of the arterial renal circulation was observed later. Since the therapeutic embolization of kidneys in patients with end-stage uremia is exceedingly risky and, therefore, unadvised, it is regarded only in the case of a bleeding polycystic kidney as implementable and more effective than nephrectomy.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 23 (2003), S. 223-228 
    ISSN: 1434-6079
    Keywords: PACS. 32.30.-r Atomic spectra – 32.70.Cs Oscillator strengths, lifetimes, transition moments – 42.62.Fi Laser spectroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We have measured the ratio between the transition probabilities of two forbidden lines in Ca: the intercombination line at 657.3 nm and the E 2 line at 457.5 nm. The value we obtained for this ratio is (54.1±2.4). Combined with the most accurate value available in literature for the lifetime of the 3 P 1 level, our measurement gives a value of (54.4±4.0) s-1 for the 1 S 0 ↦ 1 D 2 transition probability, significantly more accurate than the previous determinations.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 1988-1993 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Infinite dilution activity coefficients of aroma compounds from various chemical series were measured in model food systems (water/carbohydrates, water/polyethylene-glycols) at concentrations of various solutes. These measurements were made with a specially designed equilibrium cell. Experimental results were used to determine the parameters of group contribution thermodynamic models. The predictive capacities of the equations obtained were shown to be quite precise (8% mean deviation).
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-044X
    Keywords: Key words Replacement of ACL • Epidural analgesia • Tourniquet application • Thigh bandage • Compartment syndrome ; Schlüsselwörter Vordere Kreuzbandersatzplastik • Periduralanästhesie • Oberschenkelblutsperre • Straffer Verband • Kompartmentsyndrom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über einen Fall mit frühoperativem Kompartmentsyndroms der Tibialis-anterior-Loge mit vollständiger sensomotorischer Peronäusparese nach arthroskopisch assistierter vorderer Kreuzband (VKB-)rekonstruktion. Der Druck der Oberschenkelblutsperre betrug 360 mmHg, die Operationszeit 1,75 h. Postoperativ wurde das ganze Bein zur Thromboseprophylaxe mit einer elastischen Binde straff eingebunden. Die Analgesie erfolgte über eine kontinuierliche peridurale Bupivacain-Infusion. Unmittelbar postoperativ aufgetretene Schmerzen im Bereich des linken Unterschenkels wurden durch eine Erhöhung der Bupivacain-Menge gedämpft. Am 3. postoperativen Tag erfolgte schließlich wegen persistierender Schmerzen und unvermindert hohem Analgetikagebrauch die Verlegung ans Zentrumspital, wo bei druckdolenter und gespannter Tibialis-anterior-Loge und Kompartmentdruck über 100 mmHg die sofortige Logenspaltung durchgeführt wurde. Trotz fehlender Perfusion aller 3 Muskeln (M. tibialis anterior, M. extensor hallucis longus und M. extensor digitorum longus) wurde nur eine Logenspaltung ohne Débridement durchgeführt. Der nach 48 h durchgeführte „second-look“ zeigte nun eine partielle Reperfusion des Muskelgewebe mit Inseln ischämischer Nekrose ohne Nachweis von Kontraktilität. Klinisch bestand eine komplette Fußheberparese. Der Fall zeigt die Gefahr der Entstehung eines Kompartmentsyndroms infolge Kombination von Oberschenkelblutsperre, Arthroskopie und zu straff angelegtem Verband. Die kontinuierliche Periduralanalgesie beinhaltet dabei die Gefahr die klassischen klinischen Symptome zu verschleiern.
    Notes: Summary In this article we report a case of an early postoperative compartment syndrome of the anterior tibial compartment with complete sensomotoric palsy of the peroneal nerve after arthroscopic-assisted replacement of the anterior cruciate ligament (ACL) of the knee. The tourniquet pressure was 360 mm Hg and operation time was 1.75 h. After the operation the leg was bandaged to avoid swelling of the leg and as antithrombotic prophylaxis. Analgesic therapy was by continuous epidural bupivacaine infusion. Increasing pain of the lower leg was suppressed by additional analgesia. Due to persistent pain despite regular analgesia, the patient was sent to a main hospital on the 3rd postoperative day, where an extremely painful and swollen anterior tibial compartment with intracompartimental pressure of over 100 mm Hg was found. The compartment was released immediately. Despite the appearance of severe muscle damage, no extensive débridement was done. At the second examination, at 48 h, there was minimal perfusion of the muscles without contraction and islands of ischemic necrosis. Clinically, there was complete palsy of the dorsiflexors of the foot. The case shows the danger of a compartment syndrome when tourniquet of the limb, arthroscopy and a firm bandage are combined. Continuous epidural analgesia masks the classic symptoms of compartment syndrome.
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