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  • 1
    Electronic Resource
    Electronic Resource
    Crystal structure of the high Tc (107 K) superconducting phase in Pb-Bi-Sr-Ca-Cu-O (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 2157-2158 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The crystal structure of the high Tc superconducting phase in a Pb-doped Bi-Sr-Ca-Cu-O system (nominal composition Pb0.3Bi1.7Sr2Ca3Cu4OY) with a zero-resistance temperature of 107 K was determined with transmission electron microscopy. The investigation shows that the crystal structure, which is different from the Pb-free one, is monocline with dimensions a=0.532 nm, b=0.383 nm, c=3.71 nm, α=β=90° and γ=134.8°. A distinct change of wave vector of incommensurate modulation was also observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101516
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  • 2
    Electronic Resource
    Electronic Resource
    Crystalline phases related to a decagonal quasicrystal. I. A single-crystal X-ray diffraction study of the orthorhombic Al3Mn phase (1994)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 22-30 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108768193008729
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  • 3
    Electronic Resource
    Electronic Resource
    Structure Refinement of Monoclinic Astrophyllite (1998)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 109-114 
    Details
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The crystal structure of monoclinic magnesium astrophyllite has been redetermined. The samples were from Khibina alkaline massifs, Russia. K2NaNa(Fe,Mn)4Mg2Ti2[Si4O12]2(OH)4(OH,F)2, Mr = 1202.31, monoclinic, A2, a = 10.370 (3), b = 23.129 (5), c = 5.322 (1) Å, β = 99.55 (2)°, V = 1258.8 (5) Å3, Z = 2, Dx = 3.173 Mg m−3, Mo Kα, λ = 0.71069 Å, μ = 3.74 mm−1, F(000) = 1179, T = room temperature, R = 0.057 for 1720 reflections. The determination indicated that the coordination number of Ti is five. In tetrahedra of astrophyllite the open-branched Si—O chain connected with Ti—O semi-octahedra by corner-sharing formed a continuous sheet. Na atoms have two types of coordination. Their coordination numbers are eight and six. The Na atoms with coordination number eight are situated between layers. Other types of Na atoms are situated within the layers and form Na—O octahedra with partial occupancies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010876819700726X
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  • 4
    Electronic Resource
    Electronic Resource
    Fourier-Transform Infrared (FTIR) studies on the hydration of extractant anions in microemulsions
    Amsterdam : Elsevier
    Infrared Physics 24 (1984), S. 245-248 
    Details
    ISSN: 0020-0891
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0020-0891(84)90077-0
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  • 5
    Electronic Resource
    Electronic Resource
    Anaerobic growth and improved fermentation of Pichia stipitis bearing a URA1 gene from Saccharomyces cerevisiae (1998)
    Springer
    Applied microbiology and biotechnology 50 (1998), S. 339-345 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Respiratory and fermentative pathways co-exist to support growth and product formation in Pichia stipitis. This yeast grows rapidly without ethanol production under fully aerobic conditions, and it ferments glucose or xylose under oxygen-limited conditions, but it stops growing within one generation under anaerobic conditions. Expression of Saccharomyces cerevisiaeURA1 (ScURA1) in P. stipitis enabled rapid anaerobic growth in minimal defined medium containing glucose when essential lipids were present. ScURA1 encodes a dihydroorotate dehydrogenase that uses fumarate as an alternative electron acceptor to confer anaerobic growth. Initial P. stipitis transformants grew and produced 32 g/l ethanol from 78 g/l glucose. Cells produced even more ethanol faster following two anaerobic serial subcultures. Control strains without ScURA1 were incapable of growing anaerobically and showed only limited fermentation. P. stipitis cells bearing ScURA1 were viable in anaerobic xylose medium for long periods, and supplemental glucose allowed cell growth, but xylose alone could not support anaerobic growth even after serial anaerobic subculture on glucose. These data imply that P. stipitis can grow anaerobically using metabolic energy generated through fermentation but that it exhibits fundamental differences in cofactor selection and electron transport with glucose and xylose metabolism. This is the first report of genetic engineering to enable anaerobic growth of a eukaryote.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530051301
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  • 6
    Electronic Resource
    Electronic Resource
    A spectroscopic investigation of the formation mechanism of pigment gallstones (1997)
    New York, NY [u.a.] : Wiley-Blackwell
    Biospectroscopy 3 (1997), S. 381-391 
    Details
    ISSN: 1075-4261
    Keywords: black pigment gallstone ; FTIR ; EPR ; nonlinear phenomena ; vibrational mode ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Further spectroscopic studies of gallstones are reviewed with an emphasis on the formation of black pigment gallstones. This type of gallstone appears mainly in Western countries, with only 3% of the cholelithiasis patients in China having black gallstones. Fourier transform infrared absorption and electron paramagnetic resonance are used as spectroscopic probes of gallstones and their metal bilirubinate components. Nonlinear phenomena in gallstone formation were investigated through the appearance of ring structure in gallstones and fractal patterns in the formation in the precipitates of bile salt systems. Although a complete understanding of gallstone formation has not yet been achieved, interesting progress toward this goal has been made recently. © 1997 John Wiley & Sons, Inc. Biospectroscopy 3: 381-391, 1997
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 7
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    Cdc7 in Smooth Muscle Maturation [Gene Regulation] (2013)
    The American Society for Biochemistry and Molecular Biology (ASBMB)
    Details
    Publication Date: 2013-11-30
    Description: Smooth muscle (SM) development consists of several processes, including cell fate determination, differentiation, and maturation. The molecular mechanisms controlling SM early differentiation have been studied extensively. However, little is known about the mechanism underlying SM maturation. Cell division cycle 7 (Cdc7) has been shown to regulate cell fate determination in the initial phase of transforming growth factor-β (TGF-β)-induced SM differentiation. Our present study indicates that Cdc7 also regulates SM maturation. Knockdown of Cdc7 suppresses TGF-β-induced expression of SM myosin heavy chain, a late marker of SM differentiation. Cdc7 overexpression, on the other hand, enhances SM myosin heavy chain expression. Interestingly, Cdc7 activates the mRNA expression and promoter activity of myocardin (Myocd), a master regulator of SM differentiation, whose transcription is blocked in the initial phase of the differentiation because TGF-β does not induce Myocd mRNA until after the early SM markers are induced. These data suggest that Cdc7 mediates TGF-β-induced SM maturation via activation of Myocd transcription. Mechanistically, Cdc7 physically and functionally interacts with Nkx2.5 to regulate Myocd promoter activity. Cdc7 appears to enhance Nkx2.5 binding to Myocd promoter, leading to Myocd activation. Taken together, our studies demonstrate that Cdc7 regulates the initial and late phase of SM differentiation through distinct mechanisms.
    Print ISSN: 0021-9258
    Electronic ISSN: 1083-351X
    Topics: Biology , Chemistry and Pharmacology
    Published by The American Society for Biochemistry and Molecular Biology (ASBMB)
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  • 8
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    Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites [Biophysics and Computational Biology] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-01-12
    Description: Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric cation channels, we engineered a set of cation channel pores based on the nonselective NaK channel and determined their structures to high resolution. These structures showcase an ensemble of selectivity filters with a various number of contiguous ion binding sites ranging from 2 to 4, with each individual site maintaining a geometry and ligand environment virtually identical to that of equivalent sites in K+ channel selectivity filters. Combined with single channel electrophysiology, we show that only the channel with four ion binding sites is K+ selective, whereas those with two or three are nonselective and permeate Na+ and K+ equally well. These observations strongly suggest that the number of contiguous ion binding sites in a single file is the key determinant of the channel’s selectivity properties and the presence of four sites in K+ channels is essential for highly selective and efficient permeation of K+ ions.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 9
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    Comparing the Effect of Bleach and Water Baths on Skin Barrier Function in Atopic Dermatitis: A Split-Body Randomized Controlled Trial (2016)
    Wiley-Blackwell
    Details
    Publication Date: 2016-02-16
    Description: Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with defective epidermal barrier function, characterized by decreased stratum corneum (SC) hydration, and increased TEWL (transepidermal water loss) and pH. Staphylococcus aureus (SA) skin colonization is present in nearly all cases of AD exacerbation and correlates with disease severity, 1 suggesting an infection – inflammation cycle. The use of sodium hypochlorite (bleach) bath alone and as an adjunct to intranasal mupirocin ointment is associated with reduction in AD severity, 2,3 and decreases annual skin infection cases by ten-fold. 4 In a Cochrane review on various interventions to reduce SA colonization, including oral antibiotics, topical steroids and antibiotic ointments, only bleach bath showed a significant improvement in AD severity. 5 This article is protected by copyright. All rights reserved.
    Print ISSN: 0007-0963
    Electronic ISSN: 1365-2133
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 10
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    Observation of large topologically trivial Fermi arcs in the candidate type-II Weyl semimetal WTe_{2} (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-09-15
    Description: Author(s): F. Y. Bruno, A. Tamai, Q. S. Wu, I. Cucchi, C. Barreteau, A. de la Torre, S. McKeown Walker, S. Riccò, Z. Wang, T. K. Kim, M. Hoesch, M. Shi, N. C. Plumb, E. Giannini, A. A. Soluyanov, and F. Baumberger The authors present here several advances towards a comprehensive understanding of WTe 2 . Using microfocus laser ARPES, they resolve for the first time the distinct electronic structure of both inequivalent top and bottom (001) surfaces of WTe 2 . Moreover, they demonstrate for the first time the presence of large surface state Fermi arcs on both surfaces. Using surface electronic structure calculations, they further demonstrate that these Fermi arcs are topologically trivial and that their existence is independent of the presence of type-II Weyl points in the bulk band structure. Contrary to common belief, the observation of surface state Fermi arcs is thus not suitable to robustly identify a type-II Weyl semimetal. Finally, the authors use the observation of Fermi arcs and distinct top and bottom surfaces to clarify the controversial bulk electronic structure of WTe 2 . They show that the bulk Fermi surface is formed by three-dimensional electron and hole pockets with areas that are found to be in good agreement with transport experiments, with the exception of small hole pockets that have not been observed in quantum oscillation experiments. [Phys. Rev. B 94, 121112(R)] Published Wed Sep 14, 2016
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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