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  • 1
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case is reported of a patient with impending cardiac tamponade due to vessel perforation following balloon angioplasty of an occluded venous bypass graft. Prolonged balloon inflation failed to seal the perforation. Leakage was controlled immediately by the delivery of two platinum coils into the perforation. In case of a vessel perforation during an attempt to recanalize an occluded coronary artery bypass, placement of intracoronary platinum coils to seal the perforation may prevent the development of cardiac tamponade.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of interventional cardiology 11 (1998), S. 0 
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Risk factors associated with a poor acute outcome of coronary interventions changed significantly as a result of the development of interventional techniques and adjunct pharmacological therapies. In the 1980s morphological parameters as classified by the modified AHA/ACC score were predictive of MACE. With advanced experience and technological improvements in the early 1990s only some lesion parameters retained their predictive power for balloon angioplasty. In the era of new devices some of the lesion parameters (bifurcational lesions, calcification) remained associated with a worse acute outcome, but procedure-related parameters (e.g., length of stented segment, remaining dissection) had more impact on the outcome. Some clinical parameters like age, presence of an acute coronary syndrome, and impaired left ventricular function are still predictive of a worse outcome. The impact of thrombocyte activation, which is an essential feature of the acute coronary syndrome, may be modified by application of GP IIb/IIIa inhibitors. Because of the different study designs, reported MACE rates among recently published studies differ significantly. A generalizable scoring system for risk assessment, which takes into account the different and conflicting study results, does not appear to be imminent.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-0743
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 32 patients with acute myocardial infarction, who had undergone successful intracoronary thrombolysis, the results of regional wall motion measured from contrast cineangiograms 10 to 21 days after thrombolysis were related to the results of thallium single-photon emission computed tomography (SPECT) after intravenous dipyridamole. Wall motion was measured by means of the centerline method, and thallium defect size was estimated by comparing the patient's circumferential profile with that of 20 normals. No correlation was found between ejection fraction or regional wall motion and thallium defect size. The time from symptom onset to thrombolysis was inversely correlated with the degree of hypokinesis (r=−0.51) but not with thallium defect size. In patients treated within 3 hours, hypokinesis was significantly less than in patients treated later (−1.1±0.6 SD vs −2.2±0.8 SD, p〈0.01) whereas thallium defect size was not significantly different in both groups. It is concluded that, in patients after thrombolysis, thallium defect size determined by SPECT does not reflect the degree of left ventricular dysfunction.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1912
    Keywords: Plasma catecholamines ; HPLC separation ; Enzymatic labelling ; Performance characteristics ; Comparison of methods
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 0.05 ml plasma samples are incubated with 3H-S-adenosylmethionine and catechol-O-methyl-transferase. The resulting methoxy derivatives are extracted, the extracts separated by high pressure liquid chromatography and the metanephrine fractions collected. Evaluation is performed by liquid scintillation counting of radioactivity in the respective fractions. The following performance criteria are presented: precision, accuracy, detectability (40 pg/ml for adrenaline and noradrenaline, 130 pg/ml for dopamine), linearity and day-by-day variation. Comparison with a standard method shows an excellent correlation for adrenaline and noradrenaline.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cardiovascular drugs and therapy 1 (1987), S. 177-181 
    ISSN: 1573-7241
    Keywords: dilated cardiomyopathy ; sympathetic activity ; norepinephrine ; congestive heart failure ; captopril ; hydralazine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To study the interrelationship between myocardial norepinephrine content, left ventricular (LV) and right ventricular (RV) function, morphological changes, and plasma catecholamine concentrations, 20 patients with idiopathic dilated cardiomyopathy underwent endomyocardial biopsy and ventricular angiography. The strongest correlation was found between LV ejection fraction (EF) and myocardial norepinephrine content (r=0.87; p〈0.001). Myocardial norepinephrine content was much weaker correlated to RV EF (r=.55; p〈0.005), and no correlation was found to morphological changes or plasma norepinephrine concentration. The hemodynamic and neurohumoral effects of hydralazine versus captopril after the first dose were compared in a crossover trial including 15 patients with idiopathic dilated cardiomyopathy. Hydralazine induced increases in heart rate and cardiac index (p〈0.01) and decreases in mean arterial pressure and pulmonary wedge pressure (p〈0.01 and p〈0.005, respectively). These hemodynamic effects were associated with increased plasma norepinephrine concentrations during upright exercise (p〈0.05) and increased plasma renin activity (p〈0.01). After captopril, norepinephrine plasma concentrations showed a tendency to lower levels during upright exercise, although mean arterial pressure decreased significantly (p〈0.01). These data suggest that, in patients with idiopathic dilated cardiomyopathy, myocardial norepinephrine depletion strongly reflects left ventricular dysfunction. The different patterns of neurohumoral response to hydralazine versus captopril may be important for their long-term effect and for the prognosis of patients with idiopathic dilated cardiomyopathy. It remains to be established whether the myocardial catecholamine content is differently influenced by either drug, and whether this effect is related to the drug response after long-term treatment.
    Type of Medium: Electronic Resource
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