Keywords:
Mitosis -- Regulation.
;
Meiosis.
;
Molecular biology.
;
Electronic books.
Description / Table of Contents:
Molecular Regulation of Nuclear Events in Mitosis and Meiosis presents papers from researchers in various fields engaged in the scientific study of molecular mechanisms involved in the control of nuclear events in meiotic and mitotic cell activity. Various articles in the book discuss a wide range of topics such as the development of cytoplasmic activities that control chromosome cycles during maturation of amphibian oocytes; dynamics of the nuclear lamina during mitosis and meiosis; role of protein phosphorylation in xenopus oocyte meiotic maturation; and cell cycle studies of histone modifications. Molecular and cell biologists, oncologists, and biochemists will find the book invaluable.
Type of Medium:
Online Resource
Pages:
1 online resource (390 pages)
Edition:
1st ed.
ISBN:
9781483272702
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=1817862
DDC:
574.87623
Language:
English
Note:
Front Cover -- Molecular Regulation of Nuclear Events in Mitosis and Meiosis -- Copyright Page -- Table of Contents -- Preface -- Chapter 1. Development of Cytoplasmic Activities That Control Chromosome Cycles during Maturation of Amphibian Oocytes -- I. INTRODUCTION -- II. OOCYTE MATURATION -- III. MATURATION-PROMOTING FACTOR (MPF) -- IV. CYTOSTATIC FACTOR (CSF) -- V. CONCLUDING REMARKS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 2. Dynamics of the Nuclear Lamina during Mitosis and Meiosis -- I. INTRODUCTION -- II. DYNAMICS OF THE NUCLEAR LAMINA IN MITOSIS -- III. DYNAMICS OF THE NUCLEAR LAMINA DURING MEIOTIC PROPHASE -- IV. DYNAMICS OF THE NUCLEAR LAMINA DURING EGG MATURATION AND EARLY DEVELOPMENT -- V. COMPARISON OF THE DYNAMICS OF THE NUCLEAR LAMINA DURING MITOSIS AND MEIOSIS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 3. Regulation of Nuclear Formation and Breakdown in Cell-Free Extracts of Amphibian Eggs -- I. INTRODUCTION -- IL REGULATION OF PRONUCLEAR FORMATION -- III. REGULATION OF CHROMOSOME CONDENSATION -- IV. THE ROLE OF MPF, Ca2+ IONS, AND PROTEINPHOSPHORYLATION IN CONTROLLING NUCLEAR ENVELOPE BREAKDOWN, CHROMOSOME CONDENSATION, AND SPINDLE ASSEMBLY IN CELL-FREE EXTRACTS -- V. SUMMARY -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4. Role of Protein Phosphorylation in Xenopus Oocyte Meiotic Maturation -- I. INTRODUCTION -- II. MATURATION-INHIBITING PHOSPHOPROTEINS (Mp-P) AND cAMP -- III. PROTEIN PHOSPHORYLATION AND MATURATION-PROMOTING FACTOR (MPF) ACTIVITY -- IV. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5. Maintenance of Oocyte Meiotic Arrest by Follicular Fluid Factors -- I. INTRODUCTION -- II. CHARACTERIZATION OF FOLLICULAR FLUID OOCYTE MATURATION INHIBITOR (OMI) BY USE OF ISOLATED MAMMALIAN OOCYTES.
,
III. HYPOXANTHINE IN PIG FOLLICULAR FLUID AS THE PRINCIPAL INHIBITOR OF MOUSE OOCYTE MATURATION AND THE PREVENTION OF FOLLICLE STIMULATING HORMONE (FSH) REVERSAL OF cAMP-MAINTAINED MEIOTIC ARREST -- IV. ASSAY FOR AND CHARACTERIZATION OF HUMAN FOLLICULAR FLUID OMI BY USE OF OOCYTES FROM THE AMPHIBIAN , XENOPUS LAEVIS -- V. FAILURE TO INHIBIT XENOPUS OOCYTE MATURATION BY USE OF EXOGENOUS HYPOXANTHINE IN COMBINATION WITH N6,2' -O-DIBUTYRYL-cAMP (Bt2-CYCLIC AMP) -- VI. HOW DO THE INHIBITORY FACTORS PRESENT IN FOLLICULAR FLUID MAINTAIN MEIOTIC ARREST IN OOCYTES? -- VII. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 6. Regulation of Chromatin Condensation and Decondensation in Sea Urchin Pronuclei -- I. INTRODUCTION -- II. MITOTIC AND PREMATURE CHROMOSOME CONDENSATION -- III. MALE PRONUCLEAR DECONDENSATION -- IV. CONCLUSIONS -- ADDENDUM -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7. Regulation of Mitosis by Nonhistone Protein Factors in Mammalian Cells -- I. INTRODUCTION -- II. THE MITOTIC FACTORS -- III. INHIBITORS OF THE MITOTIC FACTORS -- IV. ROLE OF PROTEIN PHOSPHORYLATION AND DEPHOSPHORYLATION IN THE REGULATION OF NUCLEAR EVENTS ASSOCIATED WITH MITOSIS AND MEIOSIS -- V. CONCLUSIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 8. Mitosis-Specific Cytoplasmic Protein Kinases -- I. INTRODUCTION -- II. IDENTIFICATION OF PROTEIN KINASES IN CELLULAR EXTRACTS -- III. CELL CYCLE SPECIFICITY OF KINASE ACTIVITIES -- IV. COMPARISON OF KINASE ACTIVITIES WITH PROTEIN KINASES IMPLICATED IN MITOTIC EVENTS -- V. COMPARISON OF KINASE ACTIVITIES WITH MITOTIC FACTORS -- VI. CONCLUSIONS AND PERSPECTIVES -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 9. Antibodies to Mitosis-Specific Phosphoproteins -- I. INTRODUCTION -- II. MONOCLONAL ANTIBODIES TO CELLS IN MITOSIS -- III. CHARACTERIZATION OF ANTIGENS REACTIVE WITH MPM-1 AND MPM-2.
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IV. CYTOLOGICAL LOCALIZATION OF ANTIGENS REACTIVE WITH MPM-1 AND MPM-2 -- V. BIOLOGICAL ACTIVITY OF MPM-1 AND MPM-2 ANTIBODIES -- VI. DISCUSSION -- REFERENCES -- Chapter 10. Mitosis-Specific Protein Phosphorylation Associated with Premature Chromosome Condensation in a ts Cell Cycle Mutant -- I. INTRODUCTION -- II. ISOLATION AND PRELIMINARY CHARACTERIZATIONOF THE tsBN2 CELL LINE -- III. INDUCTION OF PREMATURE CHROMOSOME CONDENSATION (PCC) IN tsBN2 CELLS AT THE NONPERMISSIVE TEMPERATURE -- IV. INDUCTION OF MITOSIS-SPECIFIC PHOSPHORYLATION IN tsBN2 CELLS BY TEMPERATURE SHIFT -- V. NEWLY SYNTHESIZED PROTEIN(S) IN tsBN2 CELLS SHOWING PCC -- VI. DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 11. Chromatin Structure and Histone Modifications through Mitosis in Plasmodia of Physarum polycephalum -- I. INTRODUCTION -- II. CHROMATIN STRUCTURE AND ORGANIZATION -- III. CONTROL OF CHROMOSOME CONDENSATION -- IV. CELL CYCLE STUDIES OF HISTONE MODIFICATIONS -- V. HISTONE H1° -- VI. HISTONE H1 KINASES -- VII. DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Index.
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