Publication Date:
2013-08-17
Description:
The combination of amphotericin B at a suboptimal dose (0.3 mg/kg) with voriconazole has shown efficacy in prolonging survival and reducing tissue burden in a murine model of disseminated infection by an isolate of Aspergillus fumigatus that had showed a poor in vivo response to the azole. The efficacy of the combined treatment was higher than that obtained with amphotericin B at 0.8 mg/kg.
Print ISSN:
0066-4804
Electronic ISSN:
1098-6596
Topics:
Biology
,
Medicine
Permalink