ISSN:
1022-1352
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
New ionic telomeric surfactants derived from acryloylamino acids were synthesized and their tensioactive properties compared to those of non-ionic analogs previously reported. We also compared their anti HIV behavior with that of other polymeric polyanionic derivatives. Acryloyl monomers of various amino acids such as glycine, alanine, aspartic, glutamic and γ-aminobutyric acid were prepared and telomerized in the presence of various alkanes or perfluoroalkanethiols as chain transfer reagents. For a given amino acid, the critical micellar concentration (CMC) was shown to depend upon the nature and the length of the hydrophobic tail and not the size of the hydrophilic head, i.e., the number average degree of polymerization (DPn). None of the telomeric polyanionic derivatives reported herein induced HIV inhibition.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/macp.1995.021961123
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