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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 22 (1995), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. There is no experimental proof that renal insufficiency is a necessary condition for hypertension during erythropoietin treatment.2. The present study compares the effect of 3 weeks treatment with r-hu EPO (50i.u./kg) on systolic blood pressure (SBP), haematocrit and plasma cGMP in an animal model of chronic renal failure (remnant kidney model excision) and sham-operated rats.3. Sub-total nephrectomy induced a significant fall in haematocrit and a significant increase in plasma creatinine levels. Treatment with r-hu EPO resulted in a significant haematocrit increase in uraemic as well as in non-uraemic rats. Despite this effect, r-hu EPO treatment had no effect on SBP in sham-operated rats. On the contrary, this treatment caused significant SBP elevation in uraemic ratq in these rats, SBP increase did not correlate with haematocrit increase.4. Plasma cGMP concentrations were significantly higher in uraemic compared to sham-operated rats and were not modified by r-hu EPO treatment.5. This study provides evidence that renal insufficiency in rats is a prerequisite for the development of hypertension during erythropoietin treatment.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Während der Schwangerschaft wird ein Screening bezüglich Proteinurie allgemein empfohlen. Die Sulfosalyzilsäurenmethodik (SSA) ist diesbezüglich eine einfache und zuverlässige Methode. In afrikanischen Verhältnissen wird vor allem die Essigsäurenmethodik angewahdt. Sie ist jedoch nicht zuverlässig; so waren in einem Gesundheitszentrum in Mali 66% der Resultate positiv. Um die mit SSA erhobenen Resultate zu validieren, wurden sie nicht nur in einer Schule in Kamerun, sondern auch in einem Labor in der Schweiz bestimmt. Die Übereinstimmung der Analyse war hoch. Die Einführung des Harneiweiss-Screenings mittels SSA in einem Gesundheitszentrum in einer Stadt in Mali hat sich seither ebenfalls bewährt.
    Abstract: Résumé Le dépistage de la protéinurie est une mesures de surveillance de la grossesse largement recommandée. La méthode de dépistage à l'acide acétique n'est pas fiable: dans un centre de santé au Mali, 66% des examens étaient positífs. La méthode à l'acide sulfo-salicylique (ASS) rèprésente une alternative simpe et fiable. Nous avons comparé les resultats de la méthode ASS avec des bandelettes reactives: 1. dans un laboratoire en Suisse, 2. en milieu scolaire au Cameroun. La proportion d'accord entre les deus examens était, respectivement: 1. de 82% (66–98); 2. de 90% (83–96). Son introduction dans les Centres de SMI d'une ville du Mali a permis une amélioration durable de la qualité de la surveíllance des grossesses. Cette expérience confirme qu'il s'agit d'une méthode simple, facile à démontrer et à rèaliser et très bon marché.
    Notes: Summary Screening for proteinuria is widely recommended in the monitoring of pregnancy in order to detect preeclampsia. The method often used in primary health care centers (urine heated with acetic acid) has often attained results of over 50% positive cases. This result indicates a considerable lack of specificity outside highly endemic, for urinary schistosomiasis areas. The sulfosalicylic acid test (SSA) represents a simple, reliable and inexpensive alternative. In order to validade this procedure in the conditions of a primary mother and child health (MCH) center, results of the SSA method were compared with standard commercial strip tests a. in a well equipped Swiss laboratory, b. in a school setting in Northern Cameroom. The proportion of agreement between the two methods was 82% (Cl66–88) and 90% (Cl83–96) respectively. The relatively easy implementation of the SSA test in a MCH center in an urban area in Southern Mali lead to results more compatible with what was expected epidemiologically (less than 5% from positive to highly positive results). This experiment confirms that the SSA technique is a simple method, easy to demonstrate and implement, as well as inexpensive. Consequences for monitoring of pregnancies in such conditions are finally discussed.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2021-02-08
    Description: Air masses in the convective outflows of four large convective systems near Borneo Island in Malaysia were sampled in the height range 11–13 km within the frame of the SHIVA (Stratospheric Ozone: Halogen Impacts in a Varying Atmosphere) FP7 European project in November and December 2011. Correlated enhancements of CO, CH4 and the short-lived halogen species (CH3I and CHBr3) were detected when the aircraft crossed the anvils of the four systems. These enhancements were interpreted as the fingerprint of vertical transport from the boundary layer by the convective updraft and then horizontal advection in the outflow. For the four observations, the fraction f of air from the boundary layer ranged between 15 and 67%, showing the variability in transport efficiency depending on the dynamics of the convective system.
    Type: Article , PeerReviewed , info:eu-repo/semantics/article
    Format: text
    Format: text
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