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  • 1
    Electronic Resource
    Electronic Resource
    Microscopic evaluation of the healing and revascularization of free gingival grafts (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 3 (1968), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The objective of this study was to observe the microscopic appearance of the healing and revascularization of free gingival grafts when placed over periosteum. Seven rhesus monkeys were used to provide observation periods of 0, 2, 4, 5, 7, 8, 11, 14, 17, 21, 28, and 42 days following surgery. After dissection and excision of a split flap in the anterior region to prepare the graft bed, a mucoperiosteal graft of attached gingiva from the buccal of the premolar area was sutured in place. The animals were injected with carbon serum just before sacrifice and after preparation the histologic and cleared specimens were studied under the microscope.The results indicate that the healing and revascularization of free gingival graft and skin grafts are similar. Cellular nutrition was maintained for the first few days by a “plasmatic” circulation. Revascularization occured initially by anastomoses between vessels of the graft bed and pre-existing vessels in the graft and later by capillary budding which penetrated the graft. Carbon serum was present in the vessels of the graft at four days. There was increasing vascular density up to seven days followed by a gradual reduction and return to a normal vascular pattern after 14 days. The graft was initially separated from the bed by a thin layer of fibrinous exudate. Fibroblasts proliferated into the area and a firm fibrous union to the periosteum was apparent between 7–11 days. Initial disintegration of most of the graft epithelium ccured. Re-epithelialization resulted from migration of new epithelium from adjacent gingiva and from surviving basal cells of the graft epithelium. The epithelium had a relatively normal appearance by 14 days although new keratinization was not apparent for 28 days. The connective tissue disintegrated in portion of some of the graft and was replaced by granulation tissue which delayed healing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1968.tb01908.x
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  • 2
    Electronic Resource
    Electronic Resource
    Periodontal diseases and tooth loss (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Periodontology 2000 2 (1993), S. 0 
    Details
    ISSN: 1600-0757
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0757.1993.tb00224.x
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  • 3
    Electronic Resource
    Electronic Resource
    Periodontal treatment needs (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Periodontology 2000 2 (1993), S. 0 
    Details
    ISSN: 1600-0757
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0757.1993.tb00227.x
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  • 4
    Electronic Resource
    Electronic Resource
    Prevalence of periodontal pathogens with varying metabolic control of diabetes mellitus (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 21 (1994), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. The purpose of this study was to determine the prevalence of 5 periodontal pathogens in individuals with diabetes mellitus. Subjects (n= 107) 20–70 years of age with type 1 (n= 60) or 2 (n= 47) diabetes mellitus were studied for the occurrence of the periodontal pathogens A. actinomycetemcomitans, F. nude-alum, E. corrodens, P. gingivalis and P. intermedia. Subgingival plaque was sampled in each subject from a single site exhibiting the greatest inflammation. The evaluation of selected periodontal bacterial pathogens was based on an immunoassay utilizing bacterial specific monoclonal antibodies. 35% of the sites harbored P. gingivalis, 28%F. nucleatum and 21%E. corrodens. A. actinomycetemcomitans and P. intermedia were found in less than 10% of the sites. Subjects for whom the probing depth at the sampled site was 〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:03036979:JCPE375:ges" location="ges.gif"/〉 4 mm were more often found to have detectable pathogens than those with a probing depth 〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:03036979:JCPE375:les" location="les.gif"/〉 3 mm. Diabetic factors such as duration, type and metabolic control of the disease had no statistically significant effect on the prevalence of these bacteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1994.tb00732.x
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  • 5
    Electronic Resource
    Electronic Resource
    Long-term control of diabetes mellitus and periodontitis (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 20 (1993), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The purpose of this study was to evaluate the association between long-term control of diabetes mellitus (DM) and periodontitis, A total of 75 diabetics (Type I or II) aged 20–70 years with long-term records of their diabetic control were selected for the study. The following periodontal variables were recorded in a randomized half-mouth examination: plaque, calculus (+/−), probing depth (pd) and attachment loss (al). The mean of glycosylated hemoglobin measurements (IIbAlc) over the past 2–5 years was used to indicate the long-term control of DM. The study participants were divided into well-, moderately- and poorly-controlled diabetics. An increase in the prevalence, severity and extent of periodontitis with poorer control of diabetes was observed. The extent of calculus also increased with poorer control. In a multiple regression analysis, calculus and long-term control of diabetes were significant variables when pd≥4 mm was used as the dependent variable. Age was a significant predictor for al 〉 3 mm but not for pd ≥4 mm. Sex, duration and type of DM were not significant variables in the regression models. Less than 2% of sites with no calculus demonstrated pd≥4mm. When calculus was present, the frequency of pd ≥4 mm increased from 6% in the well-controlled diabetics to 16% in the poorly-controlled ones. We conclude that periodontitis in diabetics is associated with long-term metabolic control and presence of calculus. Therefore, regular maintenance care, including patient motivation and instruction as well as professional calculus removal, is important for diabetic patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1993.tb00384.x
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